A TGFβ-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression

por Chen, Hongshan, Lorton, Benjamin, Gupta, Varun, Shechter, David
Publicado 2016

A simplified characterization of S-adenosyl-l-methionine-consuming enzymes with 1-Step EZ-MTase: a universal and straightforward coupled-assay for in vitro and in vivo setting

por Burgos, Emmanuel S., Walters, Ryan O., Huffman, Derek M., Shechter, David
Publicado 2017

Developmental regulation of nucleoplasmin function by phosphorylation, glutamylation, and methylation

por Onikubo, Takashi, Nicklav, Joshua J, Wang, Wei-Lin, Shabanowitz, Jeffrey, Hunt, Donald F, Shechter, David
Publicado 2013

Predictors of Preventive Service Use Among Medicare Beneficiaries

por Ozminkowski, Ronald J., Goetzel, Ron Z., Shechter, David, Stapleton, David C., Baser, Onur, Lapin, Pauline
Publicado 2006

Developmental regulation of histone H2A deposition via serine-1 phosphorylation

por Wang, Wei-Lin, Nicklay, Joshua J, Anderson, Lissa, Strukl, Joe, Onikubo, Takashi, Shabanowitz, Jeffrey, Hunt, Donald F, Shechter, David
Publicado 2013

Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release

por Warren, Christopher, Matsui, Tsutomu, Karp, Jerome M., Onikubo, Takashi, Cahill, Sean, Brenowitz, Michael, Cowburn, David, Girvin, Mark, Shechter, David
Publicado 2017

Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation

por Maron, Maxim I, Casill, Alyssa D, Gupta, Varun, Roth, Jacob S, Sidoli, Simone, Query, Charles C, Gamble, Matthew J, Shechter, David
Publicado 2022

Phosphorylation and arginine methylation mark histone H2A prior to deposition during Xenopus laevis development

por Wang, Wei-Lin, Anderson, Lissa C, Nicklay, Joshua J, Chen, Hongshan, Gamble, Matthew J, Shabanowitz, Jeffrey, Hunt, Donald F, Shechter, David
Publicado 2014

Can health promotion programs save Medicare money?

por Goetzel, Ron Z, Shechter, David, Ozminkowski, Ronald J, Stapleton, David C, Lapin, Pauline J, McGinnis, J Michael, Gordon, Catherine R, Breslow, Lester
Publicado 2007

Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers

por Sun, Jian, Zhao, Yilin, McGreal, Rebecca, Cohen-Tayar, Yamit, Rockowitz, Shira, Wilczek, Carola, Ashery-Padan, Ruth, Shechter, David, Zheng, Deyou, Cvekl, Ales
Publicado 2016

Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells

por Ravichandran, Mirunalini, Lei, Run, Tang, Qin, Zhao, Yilin, Lee, Joun, Ma, Liyang, Chrysanthou, Stephanie, Lorton, Benjamin M., Cvekl, Ales, Shechter, David, Zheng, Deyou, Dawlaty, Meelad M.
Publicado 2019

Glutamylation of Npm2 and Nap1 acidic disordered regions increases DNA charge mimicry to enhance chaperone efficiency

por Lorton, Benjamin M., Warren, Christopher, Ilyas, Humaira, Nandigrami, Prithviraj, Hegde, Subray, Cahill, Sean, Lehman, Stephanie M, Shabanowitz, Jeffrey, Hunt, Donald F., Fiser, Andras, Cowburn, David, Shechter, David
Publicado 2023

WSTF regulates the function of H2A.X via a novel tyrosine kinase activity

por Xiao, Andrew, Li, Haitao, Shechter, David, Ahn, Sung Hee, Fabrizio, Laura A., Erdjument-Bromage, Hediye, Ishibe-Murakami, Satoko, Wang, Bin, Tempst, Paul, Hofmann, Kay, Patel, Dinshaw J., Elledge, Stephen J., Allis, C. David
Publicado 2008

Structure of the Arginine Methyltransferase PRMT5-MEP50 Reveals a Mechanism for Substrate Specificity

por Ho, Meng-Chiao, Wilczek, Carola, Bonanno, Jeffrey B., Xing, Li, Seznec, Janina, Matsui, Tsutomu, Carter, Lester G., Onikubo, Takashi, Kumar, P. Rajesh, Chan, Man K., Brenowitz, Michael, Cheng, R. Holland, Reimer, Ulf, Almo, Steven C., Shechter, David
Publicado 2013

Correction: Structure of the Arginine Methyltransferase PRMT5-MEP50 Reveals a Mechanism for Substrate Specificity

por Ho, Meng-Chiao, Wilczek, Carola, Bonanno, Jeffrey B., Xing, Li, Seznec, Janina, Matsui, Tsutomu, Carter, Lester G., Onikubo, Takashi, Kumar, P. Rajesh, Chan, Man K., Brenowitz, Michael, Cheng, R. Holland, Reimer, Ulf, Almo, Steven C., Shechter, David
Publicado 2013

Independent transcriptomic and proteomic regulation by type I and II protein arginine methyltransferases

por Maron, Maxim I., Lehman, Stephanie M., Gayatri, Sitaram, DeAngelo, Joseph D., Hegde, Subray, Lorton, Benjamin M., Sun, Yan, Bai, Dina L., Sidoli, Simone, Gupta, Varun, Marunde, Matthew R., Bone, James R., Sun, Zu-Wen, Bedford, Mark T., Shabanowitz, Jeffrey, Chen, Hongshan, Hunt, Donald F., Shechter, David
Publicado 2021