Clonal Hematopoiesis and the Risk of Hematologic Malignancies after Curative Therapies for Sickle Cell Disease

por Gondek, Lukasz P., Sheehan, Vivien A., Fitzhugh, Courtney D.
Publicado 2022

P1425: SYSTEMATIC INVESTIGATION OF HYDROXYUREA TREATMENT EFFECT IN PEDIATRIC PATIENTS WITH SICKLE CELL DISEASE

por Bhat, Varsha, Potdar, Alka A., Gibson, Greg, Yu, G. Karen, Sheehan, Vivien
Publicado 2023

Rheological Impact of GBT1118 Cessation in a Sickle Mouse Model

por Kanne, Celeste K., Nebor, Danitza, Pochron, Mira, Oksenberg, Donna, Sheehan, Vivien A.
Publicado 2021

Concurrent Assessment of Deformability and Adhesiveness of Sickle Red Blood Cells by Measuring Perfusion of an Adhesive Artificial Microvascular Network

por Lu, Madeleine, Kanne, Celeste K., Reddington, Riley C., Lezzar, Dalia L., Sheehan, Vivien A., Shevkoplyas, Sergey S.
Publicado 2021

Comment on: Oxygen gradient ektacytometry does not predict pain in children with sickle cell anaemia

por Sheehan, Vivien A., van Beers, Eduard J., Connes, Philippe, van Wijk, Richard, Rab, Minke A. E.
Publicado 2022

Echocardiography Differentiates Lethally Irradiated Whole-Body From Partial-Body Exposed Rats

por Inoue, Taeko, Zawaski, Janice A., Sheehan, Vivien, Kanne, Celeste, Paikari, Alireza, Kaffes, Caterina C., Sarkar, Poonam, Sabek, Omaima M., Gaber, M. Waleed
Publicado 2018

Comprehensive analysis and accurate quantification of unintended large gene modifications induced by CRISPR-Cas9 gene editing

por Park, So Hyun, Cao, Mingming, Pan, Yidan, Davis, Timothy H., Saxena, Lavanya, Deshmukh, Harshavardhan, Fu, Yilei, Treangen, Todd, Sheehan, Vivien A., Bao, Gang
Publicado 2022

OcclusionChip: A functional microcapillary occlusion assay complementary to ektacytometry for detection of small-fraction red blood cells with abnormal deformability

por Man, Yuncheng, An, Ran, Monchamp, Karamoja, Sekyonda, Zoe, Kucukal, Erdem, Federici, Chiara, Wulftange, William J., Goreke, Utku, Bode, Allison, Sheehan, Vivien A., Gurkan, Umut A.
Publicado 2022

A novel high-throughput molecular counting method with single base-pair resolution enables accurate single-gene NIPT

por Tsao, David S., Silas, Sukrit, Landry, Brian P., Itzep, Nelda P., Nguyen, Amy B., Greenberg, Samuel, Kanne, Celeste K., Sheehan, Vivien A., Sharma, Rani, Shukla, Rahul, Arora, Prem N., Atay, Oguzhan
Publicado 2019

Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease

por Park, So Hyun, Lee, Ciaran M, Dever, Daniel P, Davis, Timothy H, Camarena, Joab, Srifa, Waracharee, Zhang, Yankai, Paikari, Alireza, Chang, Alicia K, Porteus, Matthew H, Sheehan, Vivien A, Bao, Gang
Publicado 2019

Methodological aspects of the oxygenscan in sickle cell disease: A need for standardization

por Rab, Minke A.E., Kanne, Celeste K., Bos, Jennifer, Boisson, Camille, van Oirschot, Brigitte A., Nader, Elie, Renoux, Céline, Joly, Philippe, Fort, Romain, van Beers, Eduard J., Sheehan, Vivien A., van Wijk, Richard, Connes, Philippe
Publicado 2019

Whole Exome Sequencing Identifies Novel Genes for Fetal Hemoglobin Response to Hydroxyurea in Children with Sickle Cell Anemia

por Sheehan, Vivien A., Crosby, Jacy R., Sabo, Aniko, Mortier, Nicole A., Howard, Thad A., Muzny, Donna M., Dugan-Perez, Shannon, Aygun, Banu, Nottage, Kerri A., Boerwinkle, Eric, Gibbs, Richard A., Ware, Russell E., Flanagan, Jonathan M.
Publicado 2014

Oxygen gradient ektacytometry‐derived biomarkers are associated with vaso‐occlusive crises and correlate with treatment response in sickle cell disease

por Rab, Minke A. E., Kanne, Celeste K., Bos, Jennifer, van Oirschot, Brigitte A., Boisson, Camille, Houwing, Maite E., Gerritsma, Jorn, Teske, Erik, Renoux, Celine, Riedl, Jurgen, Schutgens, Roger E. G., Bartels, Marije, Nur, Erfan, Joly, Philippe, Fort, Romain, Cnossen, Marjon H., van Wijk, Richard, Connes, Philippe, van Beers, Eduard J., Sheehan, Vivien A.
Publicado 2020

Effects of Genotypes and Treatment on Oxygenscan Parameters in Sickle Cell Disease

por Boisson, Camille, Rab, Minke A. E., Nader, Elie, Renoux, Céline, Kanne, Celeste, Bos, Jennifer, van Oirschot, Brigitte A., Joly, Philippe, Fort, Romain, Gauthier, Alexandra, Stauffer, Emeric, Poutrel, Solene, Kebaili, Kamila, Cannas, Giovanna, Garnier, Nathalie, Renard, Cécile, Hequet, Olivier, Hot, Arnaud, Bertrand, Yves, van Wijk, Richard, Sheehan, Vivien A., van Beers, Eduard J., Connes, Philippe
Publicado 2021

iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays

por Fay, Meredith E., Oshinowo, Oluwamayokun, Iffrig, Elizabeth, Fibben, Kirby S., Caruso, Christina, Hansen, Scott, Musick, Jamie O., Valdez, José M., Azer, Sally S., Mannino, Robert G., Choi, Hyoann, Zhang, Dan Y., Williams, Evelyn K., Evans, Erica N., Kanne, Celeste K., Kemp, Melissa L., Sheehan, Vivien A., Carden, Marcus A., Bennett, Carolyn M., Wood, David K., Lam, Wilbur A.
Publicado 2023

Genetic regulation of fetal hemoglobin across global populations

por Cato, Liam D., Li, Rick, Lu, Henry Y., Yu, Fulong, Wissman, Mariel, Mkumbe, Baraka S., Ekwattanakit, Supachai, Deelen, Patrick, Mwita, Liberata, Sangeda, Raphael, Suksangpleng, Thidarat, Riolueang, Suchada, Bronson, Paola G., Paul, Dirk S., Kawabata, Emily, Astle, William J., Aguet, Francois, Ardlie, Kristin, de Lapuente Portilla, Aitzkoa Lopez, Kang, Guolian, Zhang, Yingze, Nouraie, Seyed Mehdi, Gordeuk, Victor R., Gladwin, Mark T., Garrett, Melanie E., Ashley-Koch, Allison, Telen, Marilyn J., Custer, Brian, Kelly, Shannon, Dinardo, Carla Luana, Sabino, Ester C., Loureiro, Paula, Carneiro-Proietti, Anna Bárbara, Maximo, Cláudia, Méndez, Adriana, Hammerer-Lercher, Angelika, Sheehan, Vivien A., Weiss, Mitchell J., Franke, Lude, Nilsson, Björn, Butterworth, Adam S., Viprakasit, Vip, Nkya, Siana, Sankaran, Vijay G.
Publicado 2023

Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease

por Nielsen, Jonas B., Rom, Oren, Surakka, Ida, Graham, Sarah E., Zhou, Wei, Roychowdhury, Tanmoy, Fritsche, Lars G., Gagliano Taliun, Sarah A., Sidore, Carlo, Liu, Yuhao, Gabrielsen, Maiken E., Skogholt, Anne Heidi, Wolford, Brooke, Overton, William, Zhao, Ying, Chen, Jin, Zhang, He, Hornsby, Whitney E., Acheampong, Akua, Grooms, Austen, Schaefer, Amanda, Zajac, Gregory J. M., Villacorta, Luis, Zhang, Jifeng, Brumpton, Ben, Løset, Mari, Rai, Vivek, Lundegaard, Pia R., Olesen, Morten S., Taylor, Kent D., Palmer, Nicholette D., Chen, Yii-Der, Choi, Seung H., Lubitz, Steven A., Ellinor, Patrick T., Barnes, Kathleen C., Daya, Michelle, Rafaels, Nicholas, Weiss, Scott T., Lasky-Su, Jessica, Tracy, Russell P., Vasan, Ramachandran S., Cupples, L. Adrienne, Mathias, Rasika A., Yanek, Lisa R., Becker, Lewis C., Peyser, Patricia A., Bielak, Lawrence F., Smith, Jennifer A., Aslibekyan, Stella, Hidalgo, Bertha A., Arnett, Donna K., Irvin, Marguerite R., Wilson, James G., Musani, Solomon K., Correa, Adolfo, Rich, Stephen S., Guo, Xiuqing, Rotter, Jerome I., Konkle, Barbara A., Johnsen, Jill M., Ashley-Koch, Allison E., Telen, Marilyn J., Sheehan, Vivien A., Blangero, John, Curran, Joanne E., Peralta, Juan M., Montgomery, Courtney, Sheu, Wayne H-H, Chung, Ren-Hua, Schwander, Karen, Nouraie, Seyed M., Gordeuk, Victor R., Zhang, Yingze, Kooperberg, Charles, Reiner, Alexander P., Jackson, Rebecca D., Bleecker, Eugene R., Meyers, Deborah A., Li, Xingnan, Das, Sayantan, Yu, Ketian, LeFaive, Jonathon, Smith, Albert, Blackwell, Tom, Taliun, Daniel, Zollner, Sebastian, Forer, Lukas, Schoenherr, Sebastian, Fuchsberger, Christian, Pandit, Anita, Zawistowski, Matthew, Kheterpal, Sachin, Brummett, Chad M., Natarajan, Pradeep, Schlessinger, David, Lee, Seunggeun, Kang, Hyun Min, Cucca, Francesco, Holmen, Oddgeir L., Åsvold, Bjørn O., Boehnke, Michael, Kathiresan, Sekar, Abecasis, Goncalo R., Chen, Y. Eugene, Willer, Cristen J., Hveem, Kristian
Publicado 2020

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

por Taliun, Daniel, Harris, Daniel N., Kessler, Michael D., Carlson, Jedidiah, Szpiech, Zachary A., Torres, Raul, Taliun, Sarah A. Gagliano, Corvelo, André, Gogarten, Stephanie M., Kang, Hyun Min, Pitsillides, Achilleas N., LeFaive, Jonathon, Lee, Seung-been, Tian, Xiaowen, Browning, Brian L., Das, Sayantan, Emde, Anne-Katrin, Clarke, Wayne E., Loesch, Douglas P., Shetty, Amol C., Blackwell, Thomas W., Smith, Albert V., Wong, Quenna, Liu, Xiaoming, Conomos, Matthew P., Bobo, Dean M., Aguet, François, Albert, Christine, Alonso, Alvaro, Ardlie, Kristin G., Arking, Dan E., Aslibekyan, Stella, Auer, Paul L., Barnard, John, Barr, R. Graham, Barwick, Lucas, Becker, Lewis C., Beer, Rebecca L., Benjamin, Emelia J., Bielak, Lawrence F., Blangero, John, Boehnke, Michael, Bowden, Donald W., Brody, Jennifer A., Burchard, Esteban G., Cade, Brian E., Casella, James F., Chalazan, Brandon, Chasman, Daniel I., Chen, Yii-Der Ida, Cho, Michael H., Choi, Seung Hoan, Chung, Mina K., Clish, Clary B., Correa, Adolfo, Curran, Joanne E., Custer, Brian, Darbar, Dawood, Daya, Michelle, de Andrade, Mariza, DeMeo, Dawn L., Dutcher, Susan K., Ellinor, Patrick T., Emery, Leslie S., Eng, Celeste, Fatkin, Diane, Fingerlin, Tasha, Forer, Lukas, Fornage, Myriam, Franceschini, Nora, Fuchsberger, Christian, Fullerton, Stephanie M., Germer, Soren, Gladwin, Mark T., Gottlieb, Daniel J., Guo, Xiuqing, Hall, Michael E., He, Jiang, Heard-Costa, Nancy L., Heckbert, Susan R., Irvin, Marguerite R., Johnsen, Jill M., Johnson, Andrew D., Kaplan, Robert, Kardia, Sharon L. R., Kelly, Tanika, Kelly, Shannon, Kenny, Eimear E., Kiel, Douglas P., Klemmer, Robert, Konkle, Barbara A., Kooperberg, Charles, Köttgen, Anna, Lange, Leslie A., Lasky-Su, Jessica, Levy, Daniel, Lin, Xihong, Lin, Keng-Han, Liu, Chunyu, Loos, Ruth J. F., Garman, Lori, Gerszten, Robert, Lubitz, Steven A., Lunetta, Kathryn L., Mak, Angel C. Y., Manichaikul, Ani, Manning, Alisa K., Mathias, Rasika A., McManus, David D., McGarvey, Stephen T., Meigs, James B., Meyers, Deborah A., Mikulla, Julie L., Minear, Mollie A., Mitchell, Braxton D., Mohanty, Sanghamitra, Montasser, May E., Montgomery, Courtney, Morrison, Alanna C., Murabito, Joanne M., Natale, Andrea, Natarajan, Pradeep, Nelson, Sarah C., North, Kari E., O’Connell, Jeffrey R., Palmer, Nicholette D., Pankratz, Nathan, Peloso, Gina M., Peyser, Patricia A., Pleiness, Jacob, Post, Wendy S., Psaty, Bruce M., Rao, D. C., Redline, Susan, Reiner, Alexander P., Roden, Dan, Rotter, Jerome I., Ruczinski, Ingo, Sarnowski, Chloé, Schoenherr, Sebastian, Schwartz, David A., Seo, Jeong-Sun, Seshadri, Sudha, Sheehan, Vivien A., Sheu, Wayne H., Shoemaker, M. Benjamin, Smith, Nicholas L., Smith, Jennifer A., Sotoodehnia, Nona, Stilp, Adrienne M., Tang, Weihong, Taylor, Kent D., Telen, Marilyn, Thornton, Timothy A., Tracy, Russell P., Van Den Berg, David J., Vasan, Ramachandran S., Viaud-Martinez, Karine A., Vrieze, Scott, Weeks, Daniel E., Weir, Bruce S., Weiss, Scott T., Weng, Lu-Chen, Willer, Cristen J., Zhang, Yingze, Zhao, Xutong, Arnett, Donna K., Ashley-Koch, Allison E., Barnes, Kathleen C., Boerwinkle, Eric, Gabriel, Stacey, Gibbs, Richard, Rice, Kenneth M., Rich, Stephen S., Silverman, Edwin K., Qasba, Pankaj, Gan, Weiniu, Papanicolaou, George J., Nickerson, Deborah A., Browning, Sharon R., Zody, Michael C., Zöllner, Sebastian, Wilson, James G., Cupples, L. Adrienne, Laurie, Cathy C., Jaquish, Cashell E., Hernandez, Ryan D., O’Connor, Timothy D., Abecasis, Gonçalo R.
Publicado 2021