A critical evaluation of methods to interpret drug combinations

por Twarog, Nathaniel R., Connelly, Michele, Shelat, Anang A.
Publicado 2020

Erratum: BRAID: A Unifying Paradigm for the Analysis of Combined Drug Action

por Twarog, Nathaniel R., Stewart, Elizabeth, Hammill, Courtney Vowell, Shelat, Anang A.
Publicado 2018

An Automated Approach to Efficiently Reformat a Large Collection of Compounds

por Cui, Jimmy, Chai, Sergio C, Shelat, Anang A, Guy, R. Kiplin, Chen, Taosheng
Publicado 2011

Robust Classification of Small-Molecule Mechanism of Action Using a Minimalist High-Content Microscopy Screen and Multidimensional Phenotypic Trajectory Analysis

por Twarog, Nathaniel R., Low, Jonathan A., Currier, Duane G., Miller, Greg, Chen, Taosheng, Shelat, Anang A.
Publicado 2016

Data vignettes for the application of response surface models in drug combination analysis

por Twarog, Nathaniel R., Martinez, Nancy E., Gartrell, Jessica, Xie, Jia, Tinkle, Christopher L., Shelat, Anang A.
Publicado 2021

Discovery of Small Molecules that Inhibit the Disordered Protein, p27(Kip1)

por Iconaru, Luigi I., Ban, David, Bharatham, Kavitha, Ramanathan, Arvind, Zhang, Weixing, Shelat, Anang A., Zuo, Jian, Kriwacki, Richard W.
Publicado 2015

Virtual-screening workflow tutorials and prospective results from the Teach-Discover-Treat competition 2014 against malaria

por Riniker, Sereina, Landrum, Gregory A., Montanari, Floriane, Villalba, Santiago D., Maier, Julie, Jansen, Johanna M., Walters, W. Patrick, Shelat, Anang A.
Publicado 2018

A High-Throughput Screen Reveals New Small-Molecule Activators and Inhibitors of Pantothenate Kinases

por Sharma, Lalit Kumar, Leonardi, Roberta, Lin, Wenwei, Boyd, Vincent A., Goktug, Asli, Shelat, Anang A., Chen, Taosheng, Jackowski, Suzanne, Rock, Charles O.
Publicado 2015

Model‐based evaluation of image‐guided fractionated whole‐brain radiation therapy in pediatric diffuse intrinsic pontine glioma xenografts

por Husband, Hillary R., Campagne, Olivia, He, Chen, Zhu, Xiaoyan, Bianski, Brandon M., Baker, Suzanne J., Shelat, Anang A., Tinkle, Christopher L., Stewart, Clinton F.
Publicado 2021

Identification of Small Molecule Activators of BMP Signaling

por Vrijens, Karen, Lin, Wenwei, Cui, Jimmy, Farmer, Dana, Low, Jonathan, Pronier, Elodie, Zeng, Fu-Yue, Shelat, Anang A., Guy, Kiplin, Taylor, Michael R., Chen, Taosheng, Roussel, Martine F.
Publicado 2013

Combination of Ribociclib with BET-Bromodomain and PI3K/mTOR Inhibitors for Medulloblastoma Treatment In Vitro and In Vivo

por Jonchere, Barbara, Williams, Justin, Zindy, Frederique, Liu, Jingjing, Robinson, Sarah, Farmer, Dana M., Min, Jaeki, Yang, Lei, Stripay, Jennifer L., Wang, Yingzhe, Freeman, Burgess B., Yu, Jiyang, Shelat, Anang A., Rankovic, Zoran, Roussel, Martine F.
Publicado 2023

MAIP: a web service for predicting blood‐stage malaria inhibitors

por Bosc, Nicolas, Felix, Eloy, Arcila, Ricardo, Mendez, David, Saunders, Martin R., Green, Darren V. S., Ochoada, Jason, Shelat, Anang A., Martin, Eric J., Iyer, Preeti, Engkvist, Ola, Verras, Andreas, Duffy, James, Burrows, Jeremy, Gardner, J. Mark F., Leach, Andrew R.
Publicado 2021

Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum

por Zhang, Jin, Bowling, John J., Smithson, David, Clark, Julie, Jacob, Melissa R., Khan, Shabana I., Tekwani, Babu L., Connelly, Michele, Samoylenko, Vladimir, Ibrahim, Mohamed A., Zaki, Mohamed A., Wang, Mei, Hester, John P., Tu, Ying, Jeffries, Cynthia, Twarog, Nathaniel, Shelat, Anang A., Walker, Larry A., Muhammad, Ilias, Guy, R. Kiplin
Publicado 2016

Orthotopic Patient-Derived Xenografts of Pediatric Solid Tumors

por Stewart, Elizabeth, Federico, Sara M., Chen, Xiang, Shelat, Anang A., Bradley, Cori, Gordon, Brittney, Karlstrom, Asa, Twarog, Nathaniel R., Clay, Michael R., Bahrami, Armita, Freeman, Burgess B., Xu, Beisi, Zhou, Xin, Wu, Jianrong, Honnell, Victoria, Ocarz, Monica, Blankenship, Kaley, Dapper, Jason, Mardis, Elaine R., Wilson, Richard K., Downing, James, Zhang, Jinghui, Easton, John, Pappo, Alberto, Dyer, Michael A.
Publicado 2017

MODL-06. Targeting c-MET in combination with radiation is effective in MET-fusion driven high-grade glioma

por Zuckermann, Marc, He, Chen, Andrews, Jared, Sloan-Henry, Roketa, Bianski, Brandon, Xie, Jia, Wang, Yingzhe, Twarog, Nathaniel, Onar-Thomas, Arzu, Ernst, Kati, Yang, Lei, Li, Yong, Dalton, James, Li, Xiaoyu, Chepyala, Divyabharathi, Zhu, Xiaoyan, Zhang, Junyuan, Xu, Ke, Hover, Laura, McKinnon, Peter J, Pfister, Stefan M, Rankovic, Zoran, Freeman, Burgess B, Shelat, Anang A, Chiang, Jason, Jones, David T W, Tinkle, Christopher L, Baker, Suzanne J
Publicado 2022

Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase

por Scott, Daniel C., Hammill, Jared T., Min, Jaeki, Rhee, David Y., Connelly, Michele, Sviderskiy, Vladislav O., Bhasin, Deepak, Chen, Yizhe, Ong, Su-Sien, Chai, Sergio C., Goktug, Asli N., Huang, Guochang, Monda, Julie K., Low, Jonathan, Kim, Ho Shin, Paulo, Joao A., Cannon, Joe R., Shelat, Anang A., Chen, Taosheng, Kelsall, Ian R., Alpi, Arno F., Pagala, Vishwajeeth, Wang, Xusheng, Peng, Junmin, Singh, Bhuvanesh, Harper, J. Wade, Schulman, Brenda A., Guy, R. Kip
Publicado 2017

Author Correction: Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia

por Kamens, Jennifer L., Nance, Stephanie, Koss, Cary, Xu, Beisi, Cotton, Anitria, Lam, Jeannie W., Garfinkle, Elizabeth A. R., Nallagatla, Pratima, Smith, Amelia M. R., Mitchell, Sharnise, Ma, Jing, Currier, Duane, Wright, William C., Kavdia, Kanisha, Pagala, Vishwajeeth R., Kim, Wonil, Wallace, LaShanale M., Cho, Ji-Hoon, Fan, Yiping, Seth, Aman, Twarog, Nathaniel, Choi, John K., Obeng, Esther A., Hatley, Mark E., Metzger, Monika L., Inaba, Hiroto, Jeha, Sima, Rubnitz, Jeffrey E., Peng, Junmin, Chen, Taosheng, Shelat, Anang A., Guy, R. Kiplin, Gruber, Tanja A.
Publicado 2023

Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia

por Kamens, Jennifer L., Nance, Stephanie, Koss, Cary, Xu, Beisi, Cotton, Anitria, Lam, Jeannie W., Garfinkle, Elizabeth A. R., Nallagatla, Pratima, Smith, Amelia M. R., Mitchell, Sharnise, Ma, Jing, Currier, Duane, Wright, William C., Kavdia, Kanisha, Pagala, Vishwajeeth R., Kim, Wonil, Wallace, LaShanale M., Cho, Ji-Hoon, Fan, Yiping, Seth, Aman, Twarog, Nathaniel, Choi, John K., Obeng, Esther A., Hatley, Mark E., Metzger, Monika L., Inaba, Hiroto, Jeha, Sima, Rubnitz, Jeffrey E., Peng, Junmin, Chen, Taosheng, Shelat, Anang A., Guy, R. Kiplin, Gruber, Tanja A.
Publicado 2023

Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma

por He, Chen, Xu, Ke, Zhu, Xiaoyan, Dunphy, Paige S., Gudenas, Brian, Lin, Wenwei, Twarog, Nathaniel, Hover, Laura D., Kwon, Chang-Hyuk, Kasper, Lawryn H., Zhang, Junyuan, Li, Xiaoyu, Dalton, James, Jonchere, Barbara, Mercer, Kimberly S., Currier, Duane G., Caufield, William, Wang, Yingzhe, Xie, Jia, Broniscer, Alberto, Wetmore, Cynthia, Upadhyaya, Santhosh A., Qaddoumi, Ibrahim, Klimo, Paul, Boop, Frederick, Gajjar, Amar, Zhang, Jinghui, Orr, Brent A., Robinson, Giles W., Monje, Michelle, Freeman III, Burgess B., Roussel, Martine F., Northcott, Paul A., Chen, Taosheng, Rankovic, Zoran, Wu, Gang, Chiang, Jason, Tinkle, Christopher L., Shelat, Anang A., Baker, Suzanne J.
Publicado 2021

Chemical genetics of Plasmodium falciparum

por Guiguemde, W. Armand, Shelat, Anang A., Bouck, David, Duffy, Sandra, Crowther, Gregory J., Davis, Paul H., Smithson, David C., Connelly, Michele, Clark, Julie, Zhu, Fangyi, Jiménez-Díaz, María B, Martinez, María S, Wilson, Emily B., Tripathi, Abhai K., Gut, Jiri, Sharlow, Elizabeth R., Bathurst, Ian, El Mazouni, Farah, Fowble, Joseph W, Forquer, Isaac, McGinley, Paula L, Castro, Steve, Angulo-Barturen, Iñigo, Ferrer, Santiago, Rosenthal, Philip J., DeRisi, Joseph L, Sullivan, David J., Lazo, John S., Roos, David S., Riscoe, Michael K., Phillips, Margaret A., Rathod, Pradipsinh K., Van Voorhis, Wesley C., Avery, Vicky M, Guy, R. Kiplin
Publicado 2010