The Structural Dynamics, Complexity of Interactions, and Functions in Cancer of Multi-SAM Containing Proteins

por Clements, Christopher M., Henen, Morkos A., Vögeli, Beat, Shellman, Yiqun G.
Publicado 2023

A simple technique for quantifying apoptosis in 96-well plates

por Ribble, Deborah, Goldstein, Nathaniel B, Norris, David A, Shellman, Yiqun G
Publicado 2005

Enrichment of Melanoma Stem-Like Cells via Sphere Assays

por Mukherjee, Nabanita, Lambert, Karoline A., Norris, David A., Shellman, Yiqun G.
Publicado 2021

A Simple Protocol for Using a LDH-Based Cytotoxicity Assay to Assess the Effects of Death and Growth Inhibition at the Same Time

por Smith, Shilo M., Wunder, Michael B., Norris, David A., Shellman, Yiqun G.
Publicado 2011

Alternative treatments for melanoma: targeting BCL-2 family members to de-bulk and kill cancer stem cells

por Mukherjee, Nabanita, Schwan, Josianna V., Fujita, Mayumi, Norris, David A., Shellman, Yiqun G.
Publicado 2015

The Combination of BH3-Mimetic ABT-737 with the Alkylating Agent Temozolomide Induces Strong Synergistic Killing of Melanoma Cells Independent of p53

por Reuland, Steven N., Goldstein, Nathaniel B., Partyka, Katie A., Cooper, David A., Fujita, Mayumi, Norris, David A., Shellman, Yiqun G.
Publicado 2011

ABT-737 synergizes with Bortezomib to kill melanoma cells

por Reuland, Steven N., Goldstein, Nathaniel B., Partyka, Katie A., Smith, Shilo, Luo, Yuchun, Fujita, Mayumi, Gonzalez, Rene, Lewis, Karl, Norris, David A., Shellman, Yiqun G.
Publicado 2011

CtBP1 is expressed in melanoma and represses the transcription of p16INK4a and Brca1

por Deng, Hui, Liu, Jing, Deng, Yu, Han, Gangwen, Shellman, Yiqun G., Robinson, Steven, Tentler, John, Robinson, William, Norris, David A., Wang, Xiao-Jing, Zhang, Qinghong
Publicado 2013

Combining a BCL2 Inhibitor with the Retinoid Derivative Fenretinide Targets Melanoma Cells Including Melanoma Initiating Cells

por Mukherjee, Nabanita, Reuland, Steven N., Lu, Yan, Luo, Yuchun, Lambert, Karoline, Fujita, Mayumi, Robinson, William A, Robinson, Steven E, Norris, David A., Shellman, Yiqun G.
Publicado 2014

MicroRNA-26a is Strongly Down-regulated in Melanoma and Induces Cell Death through Repression of Silencer of Death Domains (SODD)

por Reuland, Steven N., Smith, Shilo, Bemis, Lynne, Goldstein, Nathaniel B., Almeida, Adam, Partyka, Katie A, Marquez, Victor E., Zhang, Qinghong, Norris, David A., Shellman, Yiqun G.
Publicado 2012

NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma

por Zhai, Zili, Liu, Weimin, Kaur, Manjinder, Luo, Yuchun, Domenico, Joanne, Samson, Jenny Mae, Shellman, Yiqun G, Norris, David A, Dinarello, Charles A, Spritz, Richard A, Fujita, Mayumi
Publicado 2017

Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells

por Mukherjee, Nabanita, Lu, Yan, Almeida, Adam, Lambert, Karoline, Shiau, Chung-Wai, Su, Jung-Chen, Luo, Yuchun, Fujita, Mayumi, Robinson, William A., Robinson, Steven E., Norris, David A., Shellman, Yiqun G.
Publicado 2016

A Novel Regimen for Treating Melanoma: MCL1 Inhibitors and Azacitidine

por Dart, Chiara R., Mukherjee, Nabanita, Amato, Carol M., Goulding, Anabel, MacBeth, Morgan, Van Gulick, Robert, Couts, Kasey L., Lambert, James R., Norris, David A., Robinson, William A., Shellman, Yiqun G.
Publicado 2021

BH3 mimetics induce apoptosis independent of DRP-1 in melanoma

por Mukherjee, Nabanita, Strosnider, Andrew, Vagher, Bay, Lambert, Karoline A., Slaven, Sarah, Robinson, William A., Amato, Carol M., Couts, Kasey L., Bemis, Judson G. T., Turner, Jacqueline A., Norris, David A., Shellman, Yiqun G.
Publicado 2018

Combining a GSI and BCL-2 inhibitor to overcome melanoma's resistance to current treatments

por Mukherjee, Nabanita, Almeida, Adam, Partyka, Katie A., Lu, Yan, Schwan, Josianna V., Lambert, Karoline, Rogers, Madison, Robinson, William A, Robinson, Steven E, Applegate, Allison J, Amato, Carol M, Luo, Yuchun, Fujita, Mayumi, Norris, David A., Shellman, Yiqun G.
Publicado 2016

Simultaneously Inhibiting BCL2 and MCL1 Is a Therapeutic Option for Patients with Advanced Melanoma

por Mukherjee, Nabanita, Amato, Carol M., Skees, Jenette, Todd, Kaleb J., Lambert, Karoline A., Robinson, William A., Van Gulick, Robert, Weight, Ryan M., Dart, Chiara R., Tobin, Richard P., McCarter, Martin D., Fujita, Mayumi, Norris, David A., Shellman, Yiqun G.
Publicado 2020

SASH1 is Involved in an Autosomal Dominant Lentiginous Phenotype

por Shellman, Yiqun G., Lambert, Karoline A., Brauweiler, Anne, Fain, Pamela, Spritz, Richard A., Martini, Melanie, Janssen, Klaus-Peter, Box, Neil F., Terzian, Tamara, Rewers, Marian, Horvath, Anelia, Stratakis, Constantine A., Robinson, William A, Robinson, Steven E., Norris, David A., Artinger, Kristin B, Pacheco, Theresa R.
Publicado 2015

Pre-Treatment Mutational and Transcriptomic Landscape of Responding Metastatic Melanoma Patients to Anti-PD1 Immunotherapy

por Amato, Carol M., Hintzsche, Jennifer D., Wells, Keith, Applegate, Allison, Gorden, Nicholas T., Vorwald, Victoria M., Tobin, Richard P., Nassar, Kelsey, Shellman, Yiqun G., Kim, Jihye, Medina, Theresa M., Rioth, Matthew, Lewis, Karl D., McCarter, Martin D., Gonzalez, Rene, Tan, Aik-Choon, Robinson, William A.
Publicado 2020

MCL1 inhibitors S63845/MIK665 plus Navitoclax synergistically kill difficult-to-treat melanoma cells

por Mukherjee, Nabanita, Skees, Jenette, Todd, Kaleb J., West, Drake A., Lambert, Karoline A., Robinson, William A., Amato, Carol M., Couts, Kasey L., Van Gullick, Robert, MacBeth, Morgan, Nassar, Kelsey, Tan, Aik-Choon, Zhai, Zili, Fujita, Mayumi, Bagby, Stacey M., Dart, Chiara R., Lambert, James R., Norris, David A., Shellman, Yiqun G.
Publicado 2020

Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma

por Hintzsche, Jennifer D., Gorden, Nicholas T., Amato, Carol M., Kim, Jihye, Wuensch, Kelsey E., Robinson, Steven E., Applegate, Allison J., Couts, Kasey L., Medina, Theresa M., Wells, Keith R., Wisell, Joshua A., McCarter, Martin D., Box, Neil F., Shellman, Yiqun G., Gonzalez, Rene C., Lewis, Karl D., Tentler, John J., Tan, Aik Choon, Robinson, William A.
Publicado 2017