Automated prediction of HIV drug resistance from genotype data

por Shen, ChenHsiang, Yu, Xiaxia, Harrison, Robert W., Weber, Irene T.
Publicado 2016

Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates

por Rawi, Reda, Mall, Raghvendra, Shen, Chen-Hsiang, Farney, S. Katie, Shiakolas, Andrea, Zhou, Jing, Bensmail, Halima, Chun, Tae-Wook, Doria-Rose, Nicole A., Lynch, Rebecca M., Mascola, John R., Kwong, Peter D., Chuang, Gwo-Yu
Publicado 2019

Distinct disease features in chimpanzees infected with a precore HBV mutant associated with acute liver failure in humans

por Chen, Zhaochun, Engle, Ronald E., Shen, Chen-Hsiang, Zhao, Huaying, Schuck, Peter W., Danoff, Emily J., Nguyen, Hanh, Nishimura, Norihisa, Bock, Kevin W., Moore, Ian N., Kwong, Peter D., Purcell, Robert H., Govindarajan, Sugantha, Farci, Patrizia
Publicado 2020

Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs

por Xu, Kai, Wang, Yiran, Shen, Chen-Hsiang, Chen, Yiwei, Zhang, Baoshan, Liu, Kevin, Tsybovsky, Yaroslav, Wang, Shuishu, Farney, S. Katie, Gorman, Jason, Stephens, Tyler, Verardi, Raffaello, Yang, Yongping, Zhou, Tongqing, Chuang, Gwo-Yu, Lanzavecchia, Antonio, Piccoli, Luca, Kwong, Peter D.
Publicado 2021

Improvement of antibody functionality by structure-guided paratope engraftment

por Liu, Qingbo, Lai, Yen-Ting, Zhang, Peng, Louder, Mark K., Pegu, Amarendra, Rawi, Reda, Asokan, Mangaiarkarasi, Chen, Xuejun, Shen, Chen-Hsiang, Chuang, Gwo-Yu, Yang, Eun Sung, Miao, Huiyi, Wang, Yuge, Fauci, Anthony S., Kwong, Peter D., Mascola, John R., Lusso, Paolo
Publicado 2019

Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design

por Holt, Graham T., Gorman, Jason, Wang, Siyu, Lowegard, Anna U., Zhang, Baoshan, Liu, Tracy, Lin, Bob C., Louder, Mark K., Frenkel, Marcel S., McKee, Krisha, O’Dell, Sijy, Rawi, Reda, Shen, Chen-Hsiang, Doria-Rose, Nicole A., Kwong, Peter D., Donald, Bruce R.
Publicado 2023

Glycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies

por Wei, Qing, Hargett, Audra A., Knoppova, Barbora, Duverger, Alexandra, Rawi, Reda, Shen, Chen-Hsiang, Farney, S. Katie, Hall, Stacy, Brown, Rhubell, Keele, Brandon F., Heath, Sonya L., Saag, Michael S., Kutsch, Olaf, Chuang, Gwo-Yu, Kwong, Peter D., Moldoveanu, Zina, Raska, Milan, Renfrow, Matthew B., Novak, Jan
Publicado 2020

Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses

por Chuang, Gwo-Yu, Shen, Chen-Hsiang, Cheung, Crystal Sao-Fong, Gorman, Jason, Creanga, Adrian, Joyce, M. Gordon, Leung, Kwanyee, Rawi, Reda, Wang, Lingshu, Yang, Eun Sung, Yang, Yongping, Zhang, Baoshan, Zhang, Yi, Kanekiyo, Masaru, Zhou, Tongqing, DeKosky, Brandon J., Graham, Barney S., Mascola, John R., Kwong, Peter D.
Publicado 2021

Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain

por Kwon, Young D., Pegu, Amarendra, Yang, Eun Sung, Zhang, Baoshan, Bender, Michael F., Asokan, Mangaiarkarasi, Liu, Qingbo, McKee, Krisha, Lin, Bob C., Liu, Tracy, Louder, Mark K., Rawi, Reda, Reveiz, Mateo, Schaub, Andrew J., Shen, Chen-Hsiang, Doria-Rose, Nicole A., Lusso, Paolo, Mascola, John R., Kwong, Peter D.
Publicado 2023

Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability

por Shi, Wei, Wang, Lingshu, Zhou, Tongqing, Sastry, Mallika, Yang, Eun Sung, Zhang, Yi, Chen, Man, Chen, Xuejun, Choe, Misook, Creanga, Adrian, Leung, Kwan, Olia, Adam S., Pegu, Amarendra, Rawi, Reda, Shen, Chen-Hsiang, Stancofski, Erik-Stephane D., Talana, Chloe Adrienna, Teng, I-Ting, Wang, Shuishu, Corbett, Kizzmekia S., Tsybovsky, Yaroslav, Mascola, John R., Kwong, Peter D.
Publicado 2022

Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability

por Shi, Wei, Wang, Lingshu, Zhou, Tongqing, Sastry, Mallika, Yang, Eun Sung, Zhang, Yi, Chen, Man, Chen, Xuejun, Choe, Misook, Creanga, Adrian, Leung, Kwan, Olia, Adam S., Pegu, Amarendra, Rawi, Reda, Schön, Arne, Shen, Chen-Hsiang, Stancofski, Erik-Stephane D., Talana, Chloe Adrienna, Teng, I-Ting, Wang, Shuishu, Corbett, Kizzmekia S., Tsybovsky, Yaroslav, Mascola, John R., Kwong, Peter D.
Publicado 2022

Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site

por Banach, Bailey B., Pletnev, Sergei, Olia, Adam S., Xu, Kai, Zhang, Baoshan, Rawi, Reda, Bylund, Tatsiana, Doria-Rose, Nicole A., Nguyen, Thuy Duong, Fahad, Ahmed S., Lee, Myungjin, Lin, Bob C., Liu, Tracy, Louder, Mark K., Madan, Bharat, McKee, Krisha, O’Dell, Sijy, Sastry, Mallika, Schön, Arne, Bui, Natalie, Shen, Chen-Hsiang, Wolfe, Jacy R., Chuang, Gwo-Yu, Mascola, John R., Kwong, Peter D., DeKosky, Brandon J.
Publicado 2023

Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies

por Cottrell, Christopher A., Manne, Kartik, Kong, Rui, Wang, Shuishu, Zhou, Tongqing, Chuang, Gwo-Yu, Edwards, Robert J., Henderson, Rory, Janowska, Katarzyna, Kopp, Megan, Lin, Bob C., Louder, Mark K., Olia, Adam S., Rawi, Reda, Shen, Chen-Hsiang, Taft, Justin D., Torres, Jonathan L., Wu, Nelson R., Zhang, Baoshan, Doria-Rose, Nicole A., Cohen, Myron S., Haynes, Barton F., Shapiro, Lawrence, Ward, Andrew B., Acharya, Priyamvada, Mascola, John R., Kwong, Peter D.
Publicado 2021

Highly protective antimalarial antibodies via precision library generation and yeast display screening

por Banach, Bailey B., Tripathi, Prabhanshu, Da Silva Pereira, Lais, Gorman, Jason, Nguyen, Thuy Duong, Dillon, Marlon, Fahad, Ahmed S., Kiyuka, Patience K., Madan, Bharat, Wolfe, Jacy R., Bonilla, Brian, Flynn, Barbara, Francica, Joseph R., Hurlburt, Nicholas K., Kisalu, Neville K., Liu, Tracy, Ou, Li, Rawi, Reda, Schön, Arne, Shen, Chen-Hsiang, Teng, I-Ting, Zhang, Baoshan, Pancera, Marie, Idris, Azza H., Seder, Robert A., Kwong, Peter D., DeKosky, Brandon J.
Publicado 2022

Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life

por Zhang, Baoshan, Gollapudi, Deepika, Gorman, Jason, O’Dell, Sijy, Damron, Leland F., McKee, Krisha, Asokan, Mangaiarkarasi, Yang, Eun Sung, Pegu, Amarendra, Lin, Bob C., Chao, Cara W., Chen, Xuejun, Gama, Lucio, Ivleva, Vera B., Law, William H., Liu, Cuiping, Louder, Mark K., Schmidt, Stephen D., Shen, Chen-Hsiang, Shi, Wei, Stein, Judith A., Seaman, Michael S., McDermott, Adrian B., Carlton, Kevin, Mascola, John R., Kwong, Peter D., Lei, Q. Paula, Doria-Rose, Nicole A.
Publicado 2022

HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide

por Wang, Shuishu, Matassoli, Flavio, Zhang, Baoshan, Liu, Tracy, Shen, Chen-Hsiang, Bylund, Tatsiana, Johnston, Timothy, Henry, Amy R., Teng, I-Ting, Tripathi, Prabhanshu, Becker, Jordan E., Changela, Anita, Chaudhary, Ridhi, Cheng, Cheng, Gaudinski, Martin, Gorman, Jason, Harris, Darcy R., Lee, Myungjin, Morano, Nicholas C., Novik, Laura, O’Dell, Sijy, Olia, Adam S., Parchment, Danealle K., Rawi, Reda, Roberts-Torres, Jesmine, Stephens, Tyler, Tsybovsky, Yaroslav, Wang, Danyi, Van Wazer, David J., Zhou, Tongqing, Doria-Rose, Nicole A., Koup, Richard A., Shapiro, Lawrence, Douek, Daniel C., McDermott, Adrian B., Kwong, Peter D.
Publicado 2023

Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

por Banach, Bailey B., Cerutti, Gabriele, Fahad, Ahmed S., Shen, Chen-Hsiang, Oliveira De Souza, Matheus, Katsamba, Phinikoula S., Tsybovsky, Yaroslav, Wang, Pengfei, Nair, Manoj S., Huang, Yaoxing, Francino-Urdániz, Irene M., Steiner, Paul J., Gutiérrez-González, Matías, Liu, Lihong, López Acevedo, Sheila N., Nazzari, Alexandra F., Wolfe, Jacy R., Luo, Yang, Olia, Adam S., Teng, I-Ting, Yu, Jian, Zhou, Tongqing, Reddem, Eswar R., Bimela, Jude, Pan, Xiaoli, Madan, Bharat, Laflin, Amy D., Nimrania, Rajani, Yuen, Kwok-Yung, Whitehead, Timothy A., Ho, David D., Kwong, Peter D., Shapiro, Lawrence, DeKosky, Brandon J.
Publicado 2021

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

por Xu, Kai, Acharya, Priyamvada, Kong, Rui, Cheng, Cheng, Chuang, Gwo-Yu, Liu, Kevin, Louder, Mark K., O’Dell, Sijy, Rawi, Reda, Sastry, Mallika, Shen, Chen-Hsiang, Zhang, Baoshan, Zhou, Tongqing, Asokan, Mangaiarkarasi, Bailer, Robert T., Chambers, Michael, Chen, Xuejun, Choi, Chang W., Dandey, Venkata P., Doria-Rose, Nicole A., Druz, Aliaksandr, Eng, Edward T., Farney, Katie, Foulds, Kathryn E., Geng, Hui, Georgiev, Ivelin S., Gorman, Jason, Hill, Kurt R., Jafari, Alexander J., Kwon, Young D., Lai, Yen-Ting, Lemmin, Thomas, McKee, Krisha, Ohr, Tiffany Y., Ou, Li, Peng, Dongjun, Rowshan, Ariana P., Sheng, Zizhang, Todd, John-Paul, Tsybovsky, Yaroslav, Viox, Elise G., Wang, Yiran, Wei, Hui, Yang, Yongping, Zhou, Amy F., Chen, Rui, Yang, Lu, Scorpio, Diana G., McDermott, Adrian B., Shapiro, Lawrence, Carragher, Bridget, Potter, Clinton S., Mascola, John R., Kwong, Peter D.
Publicado 2018