Artificial intelligence, molecular subtyping, biomarkers, and precision oncology

por Shen, John Paul
Publicado 2021

Lamotrigine-induced hemophagocytic lymphohistiocytosis with Takotsubo cardiomyopathy: a case report

por Zhou, Jenny Y., Martinez, Jordan A., Shen, John Paul
Publicado 2019

Implications of Intratumor Heterogeneity on Consensus Molecular Subtype (CMS) in Colorectal Cancer

por Chowdhury, Saikat, Hofree, Matan, Lin, Kangyu, Maru, Dipen, Kopetz, Scott, Shen, John Paul
Publicado 2021

Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal Tract

por Lee, Jaewon J., Kopetz, Scott, Vilar, Eduardo, Shen, John Paul, Chen, Ken, Maitra, Anirban
Publicado 2020

Corrigendum: SemNet: Learning semantic attributes for human activity recognition with deep belief networks

por Venkatachalam, Shanmuga, Nair, Harideep, Zeng, Ming, Tan, Cathy Shunwen, Mengshoel, Ole J., Shen, John Paul
Publicado 2023

Typing tumors using pathways selected by somatic evolution

por Wang, Sheng, Ma, Jianzhu, Zhang, Wei, Shen, John Paul, Huang, Justin, Peng, Jian, Ideker, Trey
Publicado 2018

SemNet: Learning semantic attributes for human activity recognition with deep belief networks

por Venkatachalam, Shanmuga, Nair, Harideep, Zeng, Ming, Tan, Cathy Shunwen, Mengshoel, Ole J., Shen, John Paul
Publicado 2022

ERCC1 and TS Expression as Prognostic and Predictive Biomarkers in Metastatic Colon Cancer

por Choueiri, Michel B., Shen, John Paul, Gross, Andrew M., Huang, Justin K., Ideker, Trey, Fanta, Paul
Publicado 2015

Of vascular defense, hemostasis, cancer, and platelet biology: an evolutionary perspective

por Menter, David G., Afshar-Kharghan, Vahid, Shen, John Paul, Martch, Stephanie L., Maitra, Anirban, Kopetz, Scott, Honn, Kenneth V., Sood, Anil K.
Publicado 2022

The Provocative Roles of Platelets in Liver Disease and Cancer

por Kanikarla Marie, Preeti, Fowlkes, Natalie W., Afshar-Kharghan, Vahid, Martch, Stephanie L., Sorokin, Alexey, Shen, John Paul, Morris, Van K., Dasari, Arvind, You, Nancy, Sood, Anil K., Overman, Michael J., Kopetz, Scott, Menter, David George
Publicado 2021

DeMixSC: a deconvolution framework that uses single-cell sequencing plus a small benchmark dataset for improved analysis of cell-type ratios in complex tissue samples

por Guo, Shuai, Liu, Xiaoqian, Cheng, Xuesen, Jiang, Yujie, Ji, Shuangxi, Liang, Qingnan, Koval, Andrew, Li, Yumei, Owen, Leah A., Kim, Ivana K., Aparicio, Ana, Shen, John Paul, Kopetz, Scott, Weinstein, John N., DeAngelis, Margaret M., Chen, Rui, Wang, Wenyi
Publicado 2023

Clinical and Molecular Characterization of POLE Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers

por Garmezy, Benjamin, Gheeya, Jinesh, Lin, Heather Y., Huang, Yuefan, Kim, Taebeom, Jiang, Xianli, Thein, Kyaw Z., Pilié, Patrick G., Zeineddine, Fadl, Wang, Wanlin, Shaw, Kenna R., Rodon, Jordi, Shen, John Paul, Yuan, Ying, Meric-Bernstam, Funda, Chen, Ken, Yap, Timothy A.
Publicado 2022

Chemogenetic profiling identifies RAD17 as synthetically lethal with checkpoint kinase inhibition

por Shen, John Paul, Srivas, Rohith, Gross, Andrew, Li, Jianfeng, Jaehnig, Eric J., Sun, Su Ming, Bojorquez-Gomez, Ana, Licon, Katherine, Sivaganesh, Vignesh, Xu, Jia L., Klepper, Kristin, Yeerna, Huwate, Pekin, Daniel, Qiu, Chu Ping, van Attikum, Haico, Sobol, Robert W., Ideker, Trey
Publicado 2015

A global transcriptional network connecting noncoding mutations to changes in tumor gene expression

por Zhang, Wei, Bojorquez-Gomez, Ana, Velez, Daniel Ortiz, Xu, Guorong, Sanchez, Kyle S., Shen, John Paul, Chen, Kevin, Licon, Katherine, Melton, Collin, Olson, Katrina M., Yu, Michael Ku, Huang, Justin K., Carter, Hannah, Farley, Emma K., Snyder, Michael, Fraley, Stephanie I., Kreisberg, Jason F., Ideker, Trey
Publicado 2018

Efficacy of Systemic Chemotherapy in Patients With Low-grade Mucinous Appendiceal Adenocarcinoma: A Randomized Crossover Trial

por Shen, John Paul, Yousef, Abdelrahman M., Zeineddine, Fadl A., Zeineddine, Mohammad A., Tidwell, Rebecca S., Beaty, Karen A., Scofield, Lisa C., Rafeeq, Safia, Hornstein, Nicholas, Lano, Elizabeth, Eng, Cathy, Matamoros, Aurelio, Foo, Wai Chin, Uppal, Abhineet, Scally, Christopher, Mansfield, Paul, Taggart, Melissa, Raghav, Kanwal P., Overman, Michael J., Fournier, Keith
Publicado 2023

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions

por Shen, John Paul, Zhao, Dongxin, Sasik, Roman, Luebeck, Jens, Birmingham, Amanda, Bojorquez-Gomez, Ana, Licon, Katherine, Klepper, Kristin, Pekin, Daniel, Beckett, Alex, Sanchez, Kyle, Thomas, Alex, Kuo, Chih-Chung, Du, Dan, Roguev, Assen, Lewis, Nathan E., Chang, Aaron N., Kreisberg, Jason F., Krogan, Nevan, Qi, Lei, Ideker, Trey, Mali, Prashant
Publicado 2017

Survival improvement for patients with metastatic colorectal cancer over twenty years

por Zeineddine, Fadl A., Zeineddine, Mohammad A., Yousef, Abdelrahman, Gu, Yue, Chowdhury, Saikat, Dasari, Arvind, Huey, Ryan W., Johnson, Benny, Kee, Bryan, Lee, Michael S., Morelli, Maria Pia, Morris, Van K., Overman, Michael J., Parseghian, Christine, Raghav, Kanwal, Willis, Jason, Wolff, Robert A., Kawaguchi, Yoshikuni, Vauthey, Jean-Nicolas, Sun, Ryan, Kopetz, Scott, Shen, John Paul
Publicado 2023

Impact of KRAS Mutations and Co-mutations on Clinical Outcomes in Pancreatic Ductal Adenocarcinoma

por Yousef, Abdelrahman, Yousef, Mahmoud, Chowdhury, Saikat, Abdilleh, Kawther, Knafl, Mark, Edelkamp, Paul, Alfaro-Munoz, Kristin, Chacko, Ray, Peterson, Jennifer, Smaglo, Brandon G., Wolff, Robert A., Pant, Shubham, Lee, Michael S., Willis, Jason, Overman, Michael, Doss, Sudheer, Matrisian, Lynn, Hurd, Mark W., Snyder, Rebecca, Katz, Matthew H.G., Wang, Huamin, Maitra, Anirban, Shen, John Paul, Zhao, Dan
Publicado 2023

Bintrafusp Alfa, an Anti-PD-L1:TGFβ Trap Fusion Protein, in Patients with ctDNA-positive, Liver-limited Metastatic Colorectal Cancer

por Morris, Van K., Overman, Michael J., Lam, Michael, Parseghian, Christine M., Johnson, Benny, Dasari, Arvind, Raghav, Kanwal, Kee, Bryan K., Huey, Ryan, Wolff, Robert A., Shen, John Paul, Li, June, Zorrilla, Isabel, Tzeng, Ching-Wei D., Tran Cao, Hop S., Chun, Yun Shin, Newhook, Timothy E., Vauthey, Nicolas, Duose, Dzifa, Luthra, Raja, Haymaker, Cara, Kopetz, Scott
Publicado 2022