Reconstruction of evolving gene variants and fitness from short sequencing reads

por Shen, Max W., Zhao, Kevin T., Liu, David R.
Publicado 2021

Vibration-controlled Transient Elastography for Assessment of Liver Fibrosis at a USA Academic Medical Center

por Shen, Max, Lee, Anna, Lefkowitch, Jay H., Worman, Howard J.
Publicado 2022

Systematic discovery of novel eukaryotic transcriptional regulators using sequence homology independent prediction

por Bossi, Flavia, Fan, Jue, Xiao, Jun, Chandra, Lilyana, Shen, Max, Dorone, Yanniv, Wagner, Doris, Rhee, Seung Y.
Publicado 2017

Comprehensive Mapping of Key Regulatory Networks that Drive Oncogene Expression

por Lin, Lin, Holmes, Benjamin, Shen, Max W., Kammeron, Darnell, Geijsen, Niels, Gifford, David K., Sherwood, Richard I.
Publicado 2020

Machine learning based CRISPR gRNA design for therapeutic exon skipping

por Louie, Wilson, Shen, Max W., Tahiry, Zakir, Zhang, Sophia, Worstell, Daniel, Cassa, Christopher A., Sherwood, Richard I., Gifford, David K.
Publicado 2021

Small molecule inhibition of ATM kinase increases CRISPR-Cas9 1-bp insertion frequency

por Bermudez-Cabrera, Heysol C., Culbertson, Sannie, Barkal, Sammy, Holmes, Benjamin, Shen, Max W., Zhang, Sophia, Gifford, David K., Sherwood, Richard I.
Publicado 2021

Generating experimentally unrelated target molecule-binding highly functionalized nucleic-acid polymers using machine learning

por Chen, Jonathan C., Chen, Jonathan P., Shen, Max W., Wornow, Michael, Bae, Minwoo, Yeh, Wei-Hsi, Hsu, Alvin, Liu, David R.
Publicado 2022

Effect of famotidine on hospitalized patients with COVID-19: A systematic review and meta-analysis

por Chiu, Leonard, Shen, Max, Lo, Chun-Han, Chiu, Nicholas, Chen, Austin, Shin, Hyun Joon, Prsic, Elizabeth Horn, Hur, Chin, Chow, Ronald, Lebwohl, Benjamin
Publicado 2021

Peptide fusion improves prime editing efficiency

por Velimirovic, Minja, Zanetti, Larissa C., Shen, Max W., Fife, James D., Lin, Lin, Cha, Minsun, Akinci, Ersin, Barnum, Danielle, Yu, Tian, Sherwood, Richard I.
Publicado 2022

Detection of gene cis-regulatory element perturbations in single-cell transcriptomes

por Yeo, Grace Hui Ting, Juez, Oscar, Chen, Qing, Banerjee, Budhaditya, Chu, Lendy, Shen, Max W., Sabry, May, Logister, Ive, Sherwood, Richard I., Gifford, David K.
Publicado 2021

Colchicine use in patients with COVID-19: A systematic review and meta-analysis

por Chiu, Leonard, Lo, Chun-Han, Shen, Max, Chiu, Nicholas, Aggarwal, Rahul, Lee, Jihui, Choi, Young-Geun, Lam, Henry, Prsic, Elizabeth Horn, Chow, Ronald, Shin, Hyun Joon
Publicado 2021

Continuous evolution of SpCas9 variants compatible with non-G PAMs

por Miller, Shannon M., Wang, Tina, Randolph, Peyton B., Arbab, Mandana, Shen, Max W., Huang, Tony P., Matuszek, Zaneta, Newby, Gregory A., Rees, Holly A., Liu, David R.
Publicado 2020

PrimeDesign software for rapid and simplified design of prime editing guide RNAs

por Hsu, Jonathan Y., Grünewald, Julian, Szalay, Regan, Shih, Justine, Anzalone, Andrew V., Lam, Kin Chung, Shen, Max W., Petri, Karl, Liu, David R., Keith Joung, J., Pinello, Luca
Publicado 2021

Base editing rescue of spinal muscular atrophy in cells and in mice

por Arbab, Mandana, Matuszek, Zaneta, Kray, Kaitlyn M., Du, Ailing, Newby, Gregory A., Blatnik, Anton J., Raguram, Aditya, Richter, Michelle F., Zhao, Kevin T., Levy, Jonathan M., Shen, Max W., Arnold, W. David, Wang, Dan, Xie, Jun, Gao, Guangping, Burghes, Arthur H. M., Liu, David R.
Publicado 2023