Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction

por Chen, Xingchen, Sun, Pengkai, Liu, Yan, Shen, Senlin, Ma, Tengfei, Ding, Jianping
Publicado 2022

Omicron BQ.1.1 and XBB.1 unprecedentedly escape broadly neutralizing antibodies elicited by prototype vaccination

por Ju, Bin, Fan, Qing, Liu, Congcong, Shen, Senlin, Wang, Miao, Guo, Huimin, Zhou, Bing, Ge, Xiangyang, Zhang, Zheng
Publicado 2023

Cross-neutralization of SARS-CoV-2 Kappa and Delta variants by inactivated vaccine-elicited serum and monoclonal antibodies

por Cheng, Lin, Song, Shuo, Fan, Qing, Shen, Senlin, Wang, Haiyan, Zhou, Bing, Ge, Xiangyang, Ju, Bin, Zhang, Zheng
Publicado 2021

Additional mutations based on Omicron BA.2.75 mediate its further evasion from broadly neutralizing antibodies

por Guo, Huimin, Jiang, Jie, Shen, Senlin, Ge, Xiangyang, Fan, Qing, Zhou, Bing, Cheng, Lin, Ju, Bin, Zhang, Zheng
Publicado 2023

Striking antibody evasion of SARS-CoV-2 Omicron sub-lineages BQ.1.1, XBB.1 and CH.1.1

por Ju, Bin, Guo, Huimin, Wang, Miao, Fan, Qing, Shen, Senlin, Liao, Xuejiao, Jiang, Jie, Wang, Haiyan, Wang, Fuxiang, Zhang, Zheng
Publicado 2023

Increased resistance of SARS-CoV-2 Lambda variant to antibody neutralization

por Guo, Huimin, Fan, Qing, Song, Shuo, Shen, Senlin, Zhou, Bing, Wang, Haiyan, Cheng, Lin, Ge, Xiangyang, Ju, Bin, Zhang, Zheng
Publicado 2022

Identification and application of a pair of noncompeting monoclonal antibodies broadly binding to the nucleocapsid proteins of SARS-CoV-2 variants including Omicron

por Zhou, Bing, Cheng, Lin, Song, Shuo, Guo, Huimin, Shen, Senlin, Wang, Haiyan, Ge, Xiangyang, Liu, Lei, Ju, Bin, Zhang, Zheng
Publicado 2022

A key F27I substitution within HCDR1 facilitates the rapid maturation of P2C-1F11-like neutralizing antibodies in a SARS-CoV-2-infected donor

por Wang, Miao, Fan, Qing, Zhou, Bing, Ye, Haocheng, Shen, Senlin, Yu, Jiazhen, Cheng, Lin, Ge, Xiangyang, Ju, Bin, Zhang, Zheng
Publicado 2022

Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209

por Ju, Bin, Zheng, Qingbing, Guo, Huimin, Fan, Qing, Li, Tingting, Song, Shuo, Sun, Hui, Shen, Senlin, Zhou, Xinrong, Xue, Wenhui, Cui, Lingyan, Zhou, Bing, Li, Shaowei, Xia, Ningshao, Zhang, Zheng
Publicado 2022