Regulation and repurposing of nutrient sensing and autophagy in innate immunity

por Sanchez-Garrido, Julia, Shenoy, Avinash R.
Publicado 2020

A Survey of Nucleotide Cyclases in Actinobacteria: Unique Domain Organization and Expansion of the Class III Cyclase Family in Mycobacterium tuberculosis

por Shenoy, Avinash R., Sivakumar, K., Krupa, A., Srinivasan, N., Visweswariah, Sandhya S.
Publicado 2004

Genetic and pharmacological inhibition of inflammasomes reduces the survival of Mycobacterium tuberculosis strains in macrophages

por Subbarao, Sathyavani, Sanchez-Garrido, Julia, Krishnan, Nitya, Shenoy, Avinash R., Robertson, Brian D.
Publicado 2020

Vying for the control of inflammasomes: The cytosolic frontier of enteric bacterial pathogen–host interactions

por Sanchez‐Garrido, Julia, Slater, Sabrina L., Clements, Abigail, Shenoy, Avinash R., Frankel, Gad
Publicado 2020

The Atypical Ubiquitin E2 Conjugase UBE2L3 Is an Indirect Caspase-1 Target and Controls IL-1β Secretion by Inflammasomes

por Eldridge, Matthew J.G., Sanchez-Garrido, Julia, Hoben, Gil Ferreira, Goddard, Philippa J., Shenoy, Avinash R.
Publicado 2017

Human GBP1 is a microbe‐specific gatekeeper of macrophage apoptosis and pyroptosis

por Fisch, Daniel, Bando, Hironori, Clough, Barbara, Hornung, Veit, Yamamoto, Masahiro, Shenoy, Avinash R, Frickel, Eva‐Maria
Publicado 2019

Shigella sonnei O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation

por Watson, Jayne L., Sanchez-Garrido, Julia, Goddard, Philippa J., Torraca, Vincenzo, Mostowy, Serge, Shenoy, Avinash R., Clements, Abigail
Publicado 2019

Septins restrict inflammation and protect zebrafish larvae from Shigella infection

por Mazon-Moya, Maria J., Willis, Alexandra R., Torraca, Vincenzo, Boucontet, Laurent, Shenoy, Avinash R., Colucci-Guyon, Emma, Mostowy, Serge
Publicado 2017

A Probe for NLRP3 Inflammasome Inhibitor MCC950 Identifies Carbonic Anhydrase 2 as a Novel Target

por Kennedy, Cassandra R., Goya Grocin, Andrea, Kovačič, Tristan, Singh, Ravi, Ward, Jennifer A., Shenoy, Avinash R., Tate, Edward W.
Publicado 2021

Very long O‐antigen chains of Salmonella Paratyphi A inhibit inflammasome activation and pyroptotic cell death

por Mylona, Elli, Sanchez‐Garrido, Julia, Hoang Thu, Trang Nguyen, Dongol, Sabina, Karkey, Abhilasha, Baker, Stephen, Shenoy, Avinash R., Frankel, Gad
Publicado 2021

Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death

por Thurston, Teresa L. M., Matthews, Sophie A., Jennings, Elliott, Alix, Eric, Shao, Feng, Shenoy, Avinash R., Birrell, Mark A., Holden, David W.
Publicado 2016

Clustering of Tir during enteropathogenic E. coli infection triggers calcium influx–dependent pyroptosis in intestinal epithelial cells

por Zhong, Qiyun, Roumeliotis, Theodoros I., Kozik, Zuza, Cepeda-Molero, Massiel, Fernández, Luis Ángel, Shenoy, Avinash R., Bakal, Chris, Frankel, Gad, Choudhary, Jyoti S.
Publicado 2020

Enteropathogenic Escherichia coli Stimulates Effector-Driven Rapid Caspase-4 Activation in Human Macrophages

por Goddard, Philippa J., Sanchez-Garrido, Julia, Slater, Sabrina L., Kalyan, Mohini, Ruano-Gallego, David, Marchès, Olivier, Fernández, Luis Ángel, Frankel, Gad, Shenoy, Avinash R.
Publicado 2019

Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death

por Fisch, Daniel, Clough, Barbara, Domart, Marie-Charlotte, Encheva, Vesela, Bando, Hironori, Snijders, Ambrosius P., Collinson, Lucy M., Yamamoto, Masahiro, Shenoy, Avinash R., Frickel, Eva-Maria
Publicado 2020

Bacterial Virulence Factor Inhibits Caspase-4/11 Activation in Intestinal Epithelial Cells

por Pallett, Mitchell A., Crepin, Valerie F., Serafini, Nicolas, Habibzay, Maryam, Kotik, Olga, Sanchez-Garrido, Julia, Di Santo, James P., Shenoy, Avinash R., Berger, Cedric N., Frankel, Gad
Publicado 2016

IL-1β turnover by the UBE2L3 ubiquitin conjugating enzyme and HECT E3 ligases limits inflammation

por Mishra, Vishwas, Crespo-Puig, Anna, McCarthy, Callum, Masonou, Tereza, Glegola-Madejska, Izabela, Dejoux, Alice, Dow, Gabriella, Eldridge, Matthew J. G., Marinelli, Luciano H., Meng, Meihan, Wang, Shijie, Bennison, Daniel J., Morrison, Rebecca, Shenoy, Avinash R.
Publicado 2023

PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection

por Fisch, Daniel, Pfleiderer, Moritz M, Anastasakou, Eleni, Mackie, Gillian M, Wendt, Fabian, Liu, Xiangyang, Clough, Barbara, Lara-Reyna, Samuel, Encheva, Vesela, Snijders, Ambrosius P, Bando, Hironori, Yamamoto, Masahiro, Beggs, Andrew D, Mercer, Jason, Shenoy, Avinash R, Wollscheid, Bernd, Maslowski, Kendle M, Galej, Wojtek P, Frickel, Eva-Maria
Publicado 2023

E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP

por Bist, Pradeep, Cheong, Wan Shoo, Ng, Aylwin, Dikshit, Neha, Kim, Bae-Hoon, Pulloor, Niyas Kudukkil, Khameneh, Hanif Javanmard, Hedl, Matija, Shenoy, Avinash R., Balamuralidhar, Vanniarajan, Malik, Najib Bin Abdul, Hong, Michelle, Neutzner, Albert, Chin, Keh-Chuang, Kobayashi, Koichi S., Bertoletti, Antonio, Mortellaro, Alessandra, Abraham, Clara, MacMicking, John D., Xavier, Ramnik J., Sukumaran, Bindu
Publicado 2017

Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP

por Bist, Pradeep, Cheong, Wan Shoo, Ng, Aylwin, Dikshit, Neha, Kim, Bae Hoon, Pulloor, Niyas Kudukkil, Khameneh, Hanif Javanmard, Hedl, Matija, Shenoy, Avinash R., Balamuralidhar, Vanniarajan, Malik, Najib Bin Abdul, Hong, Michelle, Neutzner, Albert, Chin, Keh-Chuang, Kobayashi, Koichi S., Bertoletti, Antonio, Mortellaro, Alessandra, Abraham, Clara, MacMicking, John D., Xavier, Ramnik J., Sukumaran, Bindu
Publicado 2017