β-Cells retain a pool of insulin-containing secretory vesicles regulated by adherens junctions and the cadherin-binding protein p120 catenin

por Dissanayake, Waruni C., Shepherd, Peter R.
Publicado 2022

The role of adherens junction proteins in the regulation of insulin secretion

por Dissanayake, Waruni C., Sorrenson, Brie, Shepherd, Peter R.
Publicado 2018

For Better or Worse: The Potential for Dose Limiting the On-Target Toxicity of PI 3-Kinase Inhibitors

por Buchanan, Christina M., Lee, Kate L., Shepherd, Peter R.
Publicado 2019

Glucose regulates expression of pro-inflammatory genes, IL-1β and IL-12, through a mechanism involving hexosamine biosynthesis pathway-dependent regulation of α-E catenin

por Dissanayake, Waruni C., Oh, Jin Kyo, Sorrenson, Brie, Shepherd, Peter R.
Publicado 2021

Limited Metabolic Effect of the CREBRF(R457Q) Obesity Variant in Mice

por Metcalfe, Louise K., Shepherd, Peter R., Smith, Greg C., Turner, Nigel
Publicado 2022

β-catenin regulates muscle glucose transport via actin remodelling and M-cadherin binding

por Masson, Stewart W.C., Sorrenson, Brie, Shepherd, Peter R., Merry, Troy L.
Publicado 2020

Enzyme activity effects of N-terminal His-tag attached to catalytic sub-unit of phosphoinositide-3-kinase

por Dickson, James M. J., Lee, Woo-Jeong, Shepherd, Peter R., Buchanan, Christina M.
Publicado 2013

α-catenin isoforms are regulated by glucose and involved in regulating insulin secretion in rat clonal β-cell models

por Dissanayake, Waruni C., Sorrenson, Brie, Lee, Kate L., Barre, Sandra, Shepherd, Peter R.
Publicado 2020

Cetuximab produced from a goat mammary gland expression system is equally efficacious as innovator cetuximab in animal cancer models

por Wang, Qian, Gavin, William, Masiello, Nicholas, Tran, Khanh B., Laible, Götz, Shepherd, Peter R.
Publicado 2020

Efficacy of Providing the PI3K p110α Inhibitor BYL719 (Alpelisib) to Middle-Aged Mice in Their Diet

por Hedges, Christopher P., Boix, Jordi, Jaiswal, Jagdish K., Shetty, Bhoopika, Shepherd, Peter R., Merry, Troy L.
Publicado 2021

Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolism in vivo

por Smith, Greg C., Ong, Wee Kiat, Rewcastle, Gordon W., Kendall, Jackie D., Han, Weiping, Shepherd, Peter R.
Publicado 2012

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation

por Liu, Jing, Xu, Aimin, Lam, Karen Siu-Ling, Wong, Nai-Sum, Chen, Jie, Shepherd, Peter R, Wang, Yu
Publicado 2013

Response to BRAF-targeted Therapy Is Enhanced by Cotargeting VEGFRs or WNT/β-Catenin Signaling in BRAF-mutant Colorectal Cancer Models

por Tran, Khanh B., Kolekar, Sharada, Wang, Qian, Shih, Jen-Hsing, Buchanan, Christina M., Deva, Sanjeev, Shepherd, Peter R.
Publicado 2022

Evidence that RXFP4 is located in enterochromaffin cells and can regulate production and release of serotonin

por Fernando, Shalinda J.A., Wang, Qian, Hay, Debbie L., Bathgate, Ross A.D., Shepherd, Peter R., Lee, Kate L.
Publicado 2023

Oncogenic Mutations of p110α Isoform of PI 3-Kinase Upregulate Its Protein Kinase Activity

por Buchanan, Christina M., Dickson, James M. J., Lee, Woo-Jeong, Guthridge, Mark A., Kendall, Jackie D., Shepherd, Peter R.
Publicado 2013

Inhibitors of pan-PI3K Signaling Synergize with BRAF or MEK Inhibitors to Prevent BRAF-Mutant Melanoma Cell Growth

por Sweetlove, Melanie, Wrightson, Emma, Kolekar, Sharada, Rewcastle, Gordon W., Baguley, Bruce C., Shepherd, Peter R., Jamieson, Stephen M. F.
Publicado 2015

Prolonged treatment with a PI3K p110α inhibitor causes sex- and tissue-dependent changes in antioxidant content, but does not affect mitochondrial function

por Hedges, Christopher P., Pham, Toan, Shetty, Bhoopika, Masson, Stewart W.C., Hickey, Anthony J.R., Shepherd, Peter R., Merry, Troy L.
Publicado 2020

Comparison of growth factor signalling pathway utilisation in cultured normal melanocytes and melanoma cell lines

por Kim, Ji Eun, Stones, Clare, Joseph, Wayne R, Leung, Euphemia, Finlay, Graeme J, Shelling, Andrew N, Phillips, Wayne A, Shepherd, Peter R, Baguley, Bruce C
Publicado 2012

Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1

por Trevarton, AlexanderJ., Zhou, Yan, Yang, Dehua, Rewcastle, Gordon W., Flanagan, Jack U., Braithwaite, Antony, Shepherd, Peter R., Print, Cristin G., Wang, Ming-Wei, Lasham, Annette
Publicado 2019

Diverse mechanisms activate the PI 3-kinase/mTOR pathway in melanomas: implications for the use of PI 3-kinase inhibitors to overcome resistance to inhibitors of BRAF and MEK

por Tran, Khanh B., Kolekar, Sharada, Jabed, Anower, Jaynes, Patrick, Shih, Jen-Hsing, Wang, Qian, Flanagan, Jack U., Rewcastle, Gordon W., Baguley, Bruce C., Shepherd, Peter R.
Publicado 2021