Insights into high-grade serous carcinoma pathobiology using three-dimensional culture model systems

por Tomas, Emily, Shepherd, Trevor G.
Publicado 2023

Molecular and cellular mechanisms controlling integrin-mediated cell adhesion and tumor progression in ovarian cancer metastasis: a review

por Dhaliwal, Dolly, Shepherd, Trevor G.
Publicado 2021

On the path to translation: Highlights from the 2010 Canadian Conference on Ovarian Cancer Research

por Thériault, Brigitte L, Shepherd, Trevor G
Publicado 2011

Principles of dormancy evident in high-grade serous ovarian cancer

por Shepherd, Trevor G., Dick, Frederick A.
Publicado 2022

Primary culture and mRNA analysis of human ovarian cells

por Dunfield, Lesley D., Shepherd, Trevor G., Nachtigal, Mark W.
Publicado 2002

Constitutive activation of BMP signalling abrogates experimental metastasis of OVCA429 cells via reduced cell adhesion

por Shepherd, Trevor G, Mujoomdar, Michelle L, Nachtigal, Mark W
Publicado 2010

Mutant p53 murine oviductal epithelial cells induce progression of high-grade serous carcinoma and are most sensitive to simvastatin therapy in vitro and in vivo

por Pereira, Madison, Glogova, Alice, Haagsma, Jacob, Stewart, Julia, Shepherd, Trevor G., Petrik, Jim
Publicado 2023

Beclin-1 expression is retained in high-grade serous ovarian cancer yet is not essential for autophagy induction in vitro

por Correa, Rohann J. M., Valdes, Yudith Ramos, Shepherd, Trevor G., DiMattia, Gabriel E.
Publicado 2015

Activated CAMKKβ-AMPK signaling promotes autophagy in a spheroid model of ovarian tumour metastasis

por Laski, Jeremi, Singha, Bipradeb, Wang, Xu, Valdés, Yudith Ramos, Collins, Olga, Shepherd, Trevor G.
Publicado 2020

Gain-of-function p53(R175H) blocks apoptosis in a precursor model of ovarian high-grade serous carcinoma

por Haagsma, Jacob, Kolendowski, Bart, Buensuceso, Adrian, Valdes, Yudith Ramos, DiMattia, Gabriel E., Shepherd, Trevor G.
Publicado 2023

Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer

por Greenaway, James B., Virtanen, Carl, Osz, Kata, Revay, Tamas, Hardy, Daniel, Shepherd, Trevor, DiMattia, Gabriel, Petrik, Jim
Publicado 2016

Proteomic and Phosphoproteomic Reprogramming in Epithelial Ovarian Cancer Metastasis

por Frederick, Mallory I., Hovey, Owen F.J., Kakadia, Jenica H., Shepherd, Trevor G., Li, Shawn S.C., Heinemann, Ilka U.
Publicado 2023

Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C

por Kolendowski, Bart, Valdes, Yudith Ramos, Hirte, Hal, Itamochi, Hiroaki, Lee, Wonjae, Carey, Mark, Shepherd, Trevor G., DiMattia, Gabriel E.
Publicado 2020

Loss of LKB1-NUAK1 signalling enhances NF-κB activity in a spheroid model of high-grade serous ovarian cancer

por Buensuceso, Adrian, Fritz, Jamie Lee, Collins, Olga, Valdés, Yudith Ramos, Borrelli, Matthew J., DiMattia, Gabriel E., Shepherd, Trevor G.
Publicado 2022

Spatial and temporal epithelial ovarian cancer cell heterogeneity impacts Maraba virus oncolytic potential

por Tong, Jessica G., Valdes, Yudith Ramos, Sivapragasam, Milani, Barrett, John W., Bell, John C., Stojdl, David, DiMattia, Gabriel E., Shepherd, Trevor G.
Publicado 2017

Intact LKB1 activity is required for survival of dormant ovarian cancer spheroids

por Peart, Teresa, Valdes, Yudith Ramos, Correa, Rohann J. M., Fazio, Elena, Bertrand, Monique, McGee, Jacob, Préfontaine, Michel, Sugimoto, Akira, DiMattia, Gabriel E., Shepherd, Trevor G.
Publicado 2015

Evidence for differential viral oncolytic efficacy in an in vitro model of epithelial ovarian cancer metastasis

por Tong, Jessica G, Valdes, Yudith Ramos, Barrett, John W, Bell, John C, Stojdl, David, McFadden, Grant, McCart, J Andrea, DiMattia, Gabriel E, Shepherd, Trevor G
Publicado 2015

A Novel Role for NUAK1 in Promoting Ovarian Cancer Metastasis through Regulation of Fibronectin Production in Spheroids

por Fritz, Jamie Lee, Collins, Olga, Saxena, Parima, Buensuceso, Adrian, Ramos Valdes, Yudith, Francis, Kyle E., Brown, Kevin R., Larsen, Brett, Colwill, Karen, Gingras, Anne-Claude, Rottapel, Robert, Shepherd, Trevor G.
Publicado 2020

Markers of MEK inhibitor resistance in low-grade serous ovarian cancer: EGFR is a potential therapeutic target

por Fernandez, Marta Llaurado, Dawson, Amy, Hoenisch, Joshua, Kim, Hannah, Bamford, Sylvia, Salamanca, Clara, DiMattia, Gabriel, Shepherd, Trevor, Cremona, Mattia, Hennessy, Bryan, Anderson, Shawn, Volik, Stanislav, Collins, Colin C., Huntsman, David G., Carey, Mark S.
Publicado 2019

Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer

por Cook, David P., Galpin, Kristianne J. C., Rodriguez, Galaxia M., Shakfa, Noor, Wilson-Sanchez, Juliette, Echaibi, Maryam, Pereira, Madison, Matuszewska, Kathy, Haagsma, Jacob, Murshed, Humaira, Cudmore, Alison O., MacDonald, Elizabeth, Tone, Alicia, Shepherd, Trevor G., Petrik, James J., Koti, Madhuri, Vanderhyden, Barbara C.
Publicado 2023