CD47 expression is critical for CAR T-cell survival in vivo

por Beckett, Alex N, Chockley, Peter, Pruett-Miller, Shondra M, Nguyen, Phuong, Vogel, Peter, Sheppard, Heather, Krenciute, Giedre, Gottschalk, Stephen, DeRenzo, Christopher
Publicado 2023

GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells

por Ibanez, Jorge, Hebbar, Nikhil, Thanekar, Unmesha, Yi, Zhongzhen, Houke, Haley, Ward, Meghan, Nevitt, Chris, Tian, Liqing, Mack, Stephen C., Sheppard, Heather, Chiang, Jason, Velasquez, M. Paulina, Krenciute, Giedre
Publicado 2023

Haploinsufficiency of the lysosomal sialidase NEU1 results in a model of pleomorphic rhabdomyosarcoma in mice

por Machado, Eda R., van de Vlekkert, Diantha, Sheppard, Heather S., Perry, Scott, Downing, Susanna M., Laxton, Jonathan, Ashmun, Richard, Finkelstein, David B., Neale, Geoffrey A., Hu, Huimin, Harwood, Frank C., Koo, Selene C., Grosveld, Gerard C., d’Azzo, Alessandra
Publicado 2022

A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1

por Korff, Ane, Yang, Xiaojing, O’Donovan, Kevin, Gonzalez, Abner, Teubner, Brett J.W., Nakamura, Haruko, Messing, James, Yang, Fen, Carisey, Alexandre F., Wang, Yong-Dong, Patni, Tushar, Sheppard, Heather, Zakharenko, Stanislav S., Chook, Yuh Min, Taylor, J. Paul, Kim, Hong Joo
Publicado 2023

Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma

por Fang, Jie, Singh, Shivendra, Cheng, Changde, Natarajan, Sivaraman, Sheppard, Heather, Abu-Zaid, Ahmed, Durbin, Adam D., Lee, Ha Won, Wu, Qiong, Steele, Jacob, Connelly, Jon P., Jin, Hongjian, Chen, Wenan, Fan, Yiping, Pruett-Miller, Shondra M., Rehg, Jerold E., Koo, Selene C., Santiago, Teresa, Emmons, Joseph, Cairo, Stefano, Wang, Ruoning, Glazer, Evan S., Murphy, Andrew J., Chen, Taosheng, Davidoff, Andrew M., Armengol, Carolina, Easton, John, Chen, Xiang, Yang, Jun
Publicado 2023