Proteotoxic stress targeted therapy (PSTT)

por Sherman, Michael Y.
Publicado 2011

Yeast Prions: Protein Aggregation Is Not Enough

por Sherman, Michael Y
Publicado 2004

Resistance to TOP-1 Inhibitors: Good Old Drugs Still Can Surprise Us

por Kumar, Santosh, Sherman, Michael Y.
Publicado 2023

Hsp70 in cancer: back to the future

por Sherman, Michael Y., Gabai, Vladimir L.
Publicado 2014

Heat shock transcription factor HSF1 plays a critical role in HER2-induced cellular transformation and tumorigenesis

por Meng, Le, Gabai, Vladimir L., Sherman, Michael Y.
Publicado 2010

Hsp70–Bag3 Module Regulates Macrophage Motility and Tumor Infiltration via Transcription Factor LITAF and CSF1

por Avinery, Lena, Gahramanov, Valid, Hesin, Arkadi, Sherman, Michael Y.
Publicado 2022

Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer

por Yaglom, Julia A., McFarland, Christopher, Mirny, Leonid, Sherman, Michael Y.
Publicado 2014

Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesis

por Meng, Le, Hunt, Clayton, Yaglom, Julia A., Gabai, Vladimir L., Sherman, Michael Y.
Publicado 2011

Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2α via the Hsp70-Bag3 module

por Patel, Shivani, Kumar, Santosh, Baldan, Simone, Hesin, Arkadi, Yaglom, Julia, Sherman, Michael Y.
Publicado 2022

Heat Shock Protein 70 Protects from Caspase-Independent Programmed Cell Death via Suppression of Stress Kinase JNK

por Gabai, Vladimir L., Meriin, Anatoli B., Yaglom, Julia A., Mosser, Dick D., Sherman, Michael Y.
Publicado 2001

Huntingtin toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1

por Meriin, Anatoli B., Zhang, Xiaoqian, He, Xiangwei, Newnam, Gary P., Chernoff, Yury O., Sherman, Michael Y.
Publicado 2002

Intracellular Aggregation of Polypeptides with Expanded Polyglutamine Domain Is Stimulated by Stress-Activated Kinase Mekk1

por Meriin, Anatoli B., Mabuchi, Katsuhide, Gabai, Vladimir L., Yaglom, Julia A., Kazantsev, Alex, Sherman, Michael Y.
Publicado 2001

A first order phase transition mechanism underlies protein aggregation in mammalian cells

por Narayanan, Arjun, Meriin, Anatoli, Andrews, J Owen, Spille, Jan-Hendrik, Sherman, Michael Y, Cisse, Ibrahim I
Publicado 2019

A Cell Double-Barcoding System for Quantitative Evaluation of Primary Tumors and Metastasis in Animals That Uncovers Clonal-Specific Anti-Cancer Drug Effects

por Hesin, Arkadi, Kumar, Santosh, Gahramanov, Valid, Becker, Maria, Vilenchik, Maria, Alexandrov, Ilya, Yaglom, Julia, Sherman, Michael Y.
Publicado 2022

Validation of a Mathematical Model Describing the Dynamics of Chemotherapy for Chronic Lymphocytic Leukemia In Vivo

por Guzev, Ekaterina, Jadhav, Suchita Suryakant, Hezkiy, Eleonora Ela, Sherman, Michael Y., Firer, Michael A., Bunimovich-Mendrazitsky, Svetlana
Publicado 2022

Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations

por Yaglom, Julia A., Wang, Yongmei, Li, Amy, Li, Zhenghu, Monti, Stephano, Alexandrov, Ilya, Lu, Xiongbin, Sherman, Michael Y.
Publicado 2018

Author Correction: Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations

por Yaglom, Julia A., Wang, Yongmei, Li, Amy, Li, Zhenghu, Monti, Stephano, Alexandrov, Ilya, Lu, Xiongbin, Sherman, Michael Y.
Publicado 2018

ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis

por Bergholz, Johann, Zhang, Yujun, Wu, Junfeng, Meng, Le, Walsh, Erica M., Rai, Arun, Sherman, Michael Y., Xiao, Zhi-Xiong Jim
Publicado 2012

Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks

por Kumar, Santosh, Gahramanov, Valid, Patel, Shivani, Yaglom, Julia, Kaczmarczyk, Lukasz, Alexandrov, Ivan A., Gerlitz, Gabi, Salmon-Divon, Mali, Sherman, Michael Y.
Publicado 2023

MOLECULAR DETERMINANTS OF SELECTIVE CLEARANCE OF PROTEIN INCLUSIONS BY AUTOPHAGY

por Wong, Esther, Bejarano, Eloy, Rakshit, Moumita, Lee, Karen, Hanson, Hugo H., Zaarur, Nava, Phillips, Greg R., Sherman, Michael Y., Cuervo, Ana Maria
Publicado 2012