An Integrative Systems Biology and Experimental Approach Identifies Convergence of Epithelial Plasticity, Metabolism, and Autophagy to Promote Chemoresistance

por Xu, Shengnan, Ware, Kathryn E., Ding, Yuantong, Kim, So Young, Sheth, Maya U., Rao, Sneha, Chan, Wesley, Armstrong, Andrew J., Eward, William C., Jolly, Mohit Kumar, Somarelli, Jason A.
Publicado 2019

Eligibility and Implementation of Rivaroxaban for Secondary Prevention of Atherothrombosis in Clinical Practice—Insights From the CANHEART Study

por Sheth, Maya S., Yu, Bing, Chu, Anna, Porter, Joan, Tam, Derrick Y, Ferreira‐Legere, Laura E., Goodman, Shaun G., Farkouh, Michael E., Ko, Dennis T., Abdel‐Qadir, Husam, Udell, Jacob A.
Publicado 2022

A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer

por Ware, Kathryn E., Thomas, Beatrice C., Olawuni, Pelumi D., Sheth, Maya U., Hawkey, Nathan, Yeshwanth, M., Miller, Brian C., Vietor, Katherine J., Jolly, Mohit Kumar, Kim, So Young, Armstrong, Andrew J., Somarelli, Jason A.
Publicado 2023

From the Clinic to the Bench and Back Again in One Dog Year: How a Cross-Species Pipeline to Identify New Treatments for Sarcoma Illuminates the Path Forward in Precision Medicine

por Rao, Sneha R., Somarelli, Jason A., Altunel, Erdem, Selmic, Laura E., Byrum, Mark, Sheth, Maya U., Cheng, Serene, Ware, Kathryn E., Kim, So Young, Prinz, Joseph A., Devos, Nicolas, Corcoran, David L., Moseley, Arthur, Soderblom, Erik, Hsu, S. David, Eward, William C.
Publicado 2020

Loss of ATRX promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin binding

por Bartholf DeWitt, Suzanne, Hoskinson Plumlee, Sarah, Brighton, Hailey E., Sivaraj, Dharshan, Martz, E.J., Zand, Maryam, Kumar, Vardhman, Sheth, Maya U., Floyd, Warren, Spruance, Jacob V., Hawkey, Nathan, Varghese, Shyni, Ruan, Jianhua, Kirsch, David G., Somarelli, Jason A., Alman, Ben, Eward, William C.
Publicado 2022

A Comparative Oncology Drug Discovery Pipeline to Identify and Validate New Treatments for Osteosarcoma

por Somarelli, Jason A., Rupprecht, Gabrielle, Altunel, Erdem, Flamant, Etienne M., Rao, Sneha, Sivaraj, Dharshan, Lazarides, Alexander L., Hoskinson, Sarah M., Sheth, Maya U., Cheng, Serene, Kim, So Young, Ware, Kathryn E., Agarwal, Anika, Cullen, Mark M., Selmic, Laura E., Everitt, Jeffrey I., McCall, Shannon J., Eward, Cindy, Eward, William C., Hsu, David S.
Publicado 2020