DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in mice

por Szurgot, Inga, Hanke, Leo, Sheward, Daniel J., Vidakovics, Laura Perez, Murrell, Ben, McInerney, Gerald M., Liljeström, Peter
Publicado 2021

HIV Coinfection Provides Insights for the Design of Vaccine Cocktails to Elicit Broadly Neutralizing Antibodies

por Sheward, Daniel J., Hermanus, Tandile, Murrell, Ben, Garrett, Nigel, Abdool Karim, Salim S., Morris, Lynn, Moore, Penny L., Williamson, Carolyn
Publicado 2022

Frequent use of IGHV3-30-3 in SARS-CoV-2 neutralizing antibody responses

por Pushparaj, Pradeepa, Nicoletto, Andrea, Castro Dopico, Xaquin, Sheward, Daniel J., Kim, Sungyong, Ekström, Simon, Murrell, Ben, Corcoran, Martin, Karlsson Hedestam, Gunilla B.
Publicado 2023

Silver nanoparticles with excellent biocompatibility block pseudotyped SARS-CoV-2 in the presence of lung surfactant

por Gupta, Govind, Hamawandi, Bejan, Sheward, Daniel J., Murrell, Ben, Hanke, Leo, McInerney, Gerald, Blosi, Magda, Costa, Anna L., Toprak, Muhammet S., Fadeel, Bengt
Publicado 2022

Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice

por Wørzner, Katharina, Sheward, Daniel J., Schmidt, Signe Tandrup, Hanke, Leo, Zimmermann, Julie, McInerney, Gerald, Hedestam, Gunilla B. Karlsson, Murrell, Ben, Christensen, Dennis, Pedersen, Gabriel Kristian
Publicado 2021

Evasion of neutralising antibodies by omicron sublineage BA.2.75

por Sheward, Daniel J, Kim, Changil, Fischbach, Julian, Muschiol, Sandra, Ehling, Roy A, Björkström, Niklas K, Hedestam, Gunilla B Karlsson, Reddy, Sai T, Albert, Jan, Peacock, Thomas P, Murrell, Ben
Publicado 2022

Neutralisation sensitivity of the SARS-CoV-2 omicron (B.1.1.529) variant: a cross-sectional study

por Sheward, Daniel J, Kim, Changil, Ehling, Roy A, Pankow, Alec, Castro Dopico, Xaquin, Dyrdak, Robert, Martin, Darren P, Reddy, Sai T, Dillner, Joakim, Karlsson Hedestam, Gunilla B, Albert, Jan, Murrell, Ben
Publicado 2022

Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralising antibodies

por Sheward, Daniel J, Kim, Changil, Fischbach, Julian, Sato, Kenta, Muschiol, Sandra, Ehling, Roy A, Björkström, Niklas K, Hedestam, Gunilla B Karlsson, Reddy, Sai T, Albert, Jan, Peacock, Thomas P, Murrell, Ben
Publicado 2022

An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction

por Hanke, Leo, Vidakovics Perez, Laura, Sheward, Daniel J., Das, Hrishikesh, Schulte, Tim, Moliner-Morro, Ainhoa, Corcoran, Martin, Achour, Adnane, Karlsson Hedestam, Gunilla B., Hällberg, B. Martin, Murrell, Ben, McInerney, Gerald M.
Publicado 2020

Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies

por Hanke, Leo, Sheward, Daniel J., Pankow, Alec, Vidakovics, Laura Perez, Karl, Vivien, Kim, Changil, Urgard, Egon, Smith, Natalie L., Astorga-Wells, Juan, Ekström, Simon, Coquet, Jonathan M., McInerney, Gerald M., Murrell, Ben
Publicado 2022

HIV Superinfection Drives De Novo Antibody Responses and Not Neutralization Breadth

por Sheward, Daniel J., Marais, Jinny, Bekker, Valerie, Murrell, Ben, Eren, Kemal, Bhiman, Jinal N., Nonyane, Molati, Garrett, Nigel, Woodman, Zenda L., Abdool Karim, Quarraisha, Abdool Karim, Salim S., Morris, Lynn, Moore, Penny L., Williamson, Carolyn
Publicado 2018

Beta RBD boost broadens antibody-mediated protection against SARS-CoV-2 variants in animal models

por Sheward, Daniel J., Mandolesi, Marco, Urgard, Egon, Kim, Changil, Hanke, Leo, Perez Vidakovics, Laura, Pankow, Alec, Smith, Natalie L., Castro Dopico, Xaquin, McInerney, Gerald M., Coquet, Jonathan M., Karlsson Hedestam, Gunilla B., Murrell, Ben
Publicado 2021

Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages

por Chernyshev, Mark, Sakharkar, Mrunal, Connor, Ruth I., Dugan, Haley L., Sheward, Daniel J., Rappazzo, C. G., Stålmarck, Aron, Forsell, Mattias N. E., Wright, Peter F., Corcoran, Martin, Murrell, Ben, Walker, Laura M., Karlsson Hedestam, Gunilla B.
Publicado 2023

Longitudinal single-cell analysis of SARS-CoV-2–reactive B cells uncovers persistence of early-formed, antigen-specific clones

por Scharf, Lydia, Axelsson, Hannes, Emmanouilidi, Aikaterini, Mathew, Nimitha R., Sheward, Daniel J., Leach, Susannah, Isakson, Pauline, Smirnov, Ilya V., Marklund, Emelie, Miron, Nicolae, Andersson, Lars-Magnus, Gisslén, Magnus, Murrell, Ben, Lundgren, Anna, Bemark, Mats, Angeletti, Davide
Publicado 2023

SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses

por Mandolesi, Marco, Sheward, Daniel J., Hanke, Leo, Ma, Junjie, Pushparaj, Pradeepa, Perez Vidakovics, Laura, Kim, Changil, Àdori, Monika, Lenart, Klara, Loré, Karin, Castro Dopico, Xaquin, Coquet, Jonathan M., McInerney, Gerald M., Karlsson Hedestam, Gunilla B., Murrell, Ben
Publicado 2021

South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication

por Richardson, Simone I, Gray, Elin S, Mkhize, Nonhlanhla N, Sheward, Daniel J, Lambson, Bronwen E, Wibmer, Constantinos Kurt, Masson, Lindi, Werner, Lise, Garrett, Nigel, Passmore, Jo-Ann S, Karim, Quarraisha Abdool, Karim, Salim S Abdool, Williamson, Carolyn, Moore, Penny L, Morris, Lynn
Publicado 2015

Probabilistic classification of anti‐SARS‐CoV‐2 antibody responses improves seroprevalence estimates

por Castro Dopico, Xaquin, Muschiol, Sandra, Grinberg, Nastasiya F, Aleman, Soo, Sheward, Daniel J, Hanke, Leo, Ahl, Marcus, Vikström, Linnea, Forsell, Mattias, Coquet, Jonathan M, McInerney, Gerald, Dillner, Joakim, Bogdanovic, Gordana, Murrell, Ben, Albert, Jan, Wallace, Chris, Karlsson Hedestam, Gunilla B
Publicado 2022

Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies

por Pushparaj, Pradeepa, Nicoletto, Andrea, Sheward, Daniel J., Das, Hrishikesh, Castro Dopico, Xaquin, Perez Vidakovics, Laura, Hanke, Leo, Chernyshev, Mark, Narang, Sanjana, Kim, Sungyong, Fischbach, Julian, Ekström, Simon, McInerney, Gerald, Hällberg, B. Martin, Murrell, Ben, Corcoran, Martin, Karlsson Hedestam, Gunilla B.
Publicado 2023

SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despit...

por Christensen, Dennis, Polacek, Charlotta, Sheward, Daniel J., Hanke, Leo, McInerney, Gerald, Murrell, Ben, Hartmann, Katrine Top, Jensen, Henrik Elvang, Zimmermann, Julie, Jungersen, Gregers, Illigen, Kristin Engelhart, Isling, Louise Krag, Fernandez-Antunez, Carlota, Ramirez, Santseharay, Bukh, Jens, Pedersen, Gabriel Kristian
Publicado 2023

SARS-CoV-2 antibodies from children exhibit broad neutralization and belong to adult public clonotypes

por Wall, Steven C., Suryadevara, Naveenchandra, Kim, Changil, Shiakolas, Andrea R., Holt, Clinton M., Irbe, Emma B., Wasdin, Perry T., Suresh, Yukthi P., Binshtein, Elad, Chen, Elaine C., Zost, Seth J., Canfield, Elizabeth, Crowe, James E., Thompson-Arildsen, Mary Ann, Sheward, Daniel J., Carnahan, Robert H., Georgiev, Ivelin S.
Publicado 2023