Mechanistic evaluation of the inhibitory effect of four SGLT-2 inhibitors on SGLT 1 and SGLT 2 using physiologically based pharmacokinetic (PBPK) modeling approaches

por Zhang, Yu, Xie, Panpan, Li, Yamei, Chen, Zhixing, Shi, Aixin
Publicado 2023

Pharmacokinetics, Safety, and Tolerability of Single-Dose Orally Administered Venglustat in Healthy Chinese Volunteers

por Li, Yingxin, Li, Yang, Li, Li, Xue, Wei, Xin, Kong, Wang, Titi, Shi, Aixin
Publicado 2023

Safety, Tolerability, and Pharmacokinetics of Ibuprofenamine Hydrochloride Spray (NSAIDs), a New Drug for Rheumatoid Arthritis and Osteoarthritis, in Healthy Chinese Subjects

por Xie, Panpan, Xue, Wei, Qi, Wenyuan, Li, Yang, Yang, Lei, Yang, Zhaojun, Shi, Aixin
Publicado 2021

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Sotagliflozin After Multiple Ascending Doses in Chinese Healthy Subjects

por He, Xuemei, Gao, Xin, Xie, Panpan, Liu, Yuan, Bai, Wenjing, Liu, Yue, Shi, Aixin
Publicado 2022

Pharmacokinetics, Safety and Tolerability of Once-Weekly Subcutaneous Semaglutide in Healthy Chinese Subjects: A Double-Blind, Phase 1, Randomized Controlled Trial

por Shi, Aixin, Xie, Panpan, Nielsen, Lasse Lykke, Skjøth, Trine Vang, He, Xuemei, Haugaard, Sine Pfeiffer
Publicado 2020

Pharmacokinetics and Safety of iGlarLixi in Healthy Chinese Participants: Results of a Phase 1 Randomized Study

por Xie, Panpan, He, Xuemei, Gao, Xin, Shuai, Mengmeng, Schmider, Wolfgang, Jiang, Alex, Yang, Na, Shi, Aixin
Publicado 2023

Pharmacokinetics and Safety of Single and Multiple Doses of Peficitinib (ASP015K) in Healthy Chinese Subjects

por Gao, Xin, He, Xuemei, Oshima, Hiroyuki, Miyatake, Daisuke, Otsuka, Yukio, Kato, Kota, Cai, Chunxiao, Wojtkowski, Tomasz, Song, Nan, Kaneko, Yuichiro, Shi, Aixin
Publicado 2022