An IL-4/21 Inverted Cytokine Receptor Improving CAR-T Cell Potency in Immunosuppressive Solid-Tumor Microenvironment

por Wang, Yi, Jiang, Hua, Luo, Hong, Sun, Yansha, Shi, Bizhi, Sun, Ruixin, Li, Zonghai
Publicado 2019

EGFRvIII Mediates Hepatocellular Carcinoma Cell Invasion by Promoting S100 Calcium Binding Protein A11 Expression

por Luo, Xiaoying, Xie, Hailong, Long, Xiaolan, Zhou, Min, Xu, Zhibin, Shi, Bizhi, Jiang, Hua, Li, Zonghai
Publicado 2013

Efficient growth suppression in pancreatic cancer PDX model by fully human anti-mesothelin CAR-T cells

por Jiang, Hua, Song, Bo, Wang, Peng, Shi, Bizhi, Li, Qixiang, Fan, Mingliang, Di, Shengmeng, Yang, Jie, Li, Zonghai
Publicado 2017

Combined Adjuvant of Poly I:C Improves Antitumor Effects of CAR-T Cells

por Di, Shengmeng, Zhou, Min, Pan, Zeyan, Sun, Ruixin, Chen, Muhua, Jiang, Hua, Shi, Bizhi, Luo, Hong, Li, Zonghai
Publicado 2019

Chimeric anti-GPC3 sFv-CD3ε receptor-modified T cells with IL7 co-expression for the treatment of solid tumors

por Sun, Yansha, Dong, Yiwei, Sun, Ruixin, Liu, Yifan, Wang, Yi, Luo, Hong, Shi, Bizhi, Jiang, Hua, Li, Zonghai
Publicado 2022

FAP-targeted CAR-T suppresses MDSCs recruitment to improve the antitumor efficacy of claudin18.2-targeted CAR-T against pancreatic cancer

por Liu, Yifan, Sun, Yansha, Wang, Peng, Li, Songling, Dong, Yiwei, Zhou, Min, Shi, Bizhi, Jiang, Hua, Sun, Ruixin, Li, Zonghai
Publicado 2023

Target-Dependent Expression of IL12 by synNotch Receptor-Engineered NK92 Cells Increases the Antitumor Activities of CAR-T Cells

por Luo, Hong, Wu, Xiuqi, Sun, Ruixin, Su, Jingwen, Wang, Yi, Dong, Yiwei, Shi, Bizhi, Sun, Yansha, Jiang, Hua, Li, Zonghai
Publicado 2019

Adoptive immunotherapy using T lymphocytes redirected to glypican-3 for the treatment of lung squamous cell carcinoma

por Li, Kesang, Pan, Xiaorong, Bi, Yanyu, Xu, Wen, Chen, Cheng, Gao, Huiping, Shi, Bizhi, Jiang, Hua, Yang, Shengli, Jiang, Liyan, Li, Zonghai
Publicado 2015

Disruption of PD-1 Enhanced the Anti-tumor Activity of Chimeric Antigen Receptor T Cells Against Hepatocellular Carcinoma

por Guo, Xingliang, Jiang, Hua, Shi, Bizhi, Zhou, Min, Zhang, Honghong, Shi, Zhimin, Du, Guoxiu, Luo, Hong, Wu, Xiuqi, Wang, Yi, Sun, Ruixin, Li, Zonghai
Publicado 2018

Combination of an anti-EGFRvIII antibody CH12 with Rapamycin synergistically inhibits the growth of EGFRvIII(+)PTEN(−) glioblastoma in vivo

por Xu, Wen, Bi, Yanyu, Kong, Juan, Zhang, Jiqin, Wang, Biao, Li, Kesang, Tian, Mi, Pan, Xiaorong, Shi, Bizhi, Gu, Jianren, Jiang, Hua, Kong, Xianming, Li, Zonghai
Publicado 2016

EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer

por Zhang, Jiqin, Song, Fei, Zhao, Xiaojing, Jiang, Hua, Wu, Xiuqi, Wang, Biao, Zhou, Min, Tian, Mi, Shi, Bizhi, Wang, Huamao, Jia, Yuanhui, Wang, Hai, Pan, Xiaorong, Li, Zonghai
Publicado 2017

Synergistic antitumor efficacy against the EGFRvIII(+)HER2(+) breast cancers by combining trastuzumab with anti-EGFRvIII antibody CH12

por Xu, Wen, Bi, Yanyu, Zhang, Jiqin, Kong, Juan, Jiang, Hua, Tian, Mi, Li, Kesang, Wang, Biao, Chen, Cheng, Song, Fei, Pan, Xiaorong, Shi, Bizhi, Kong, Xianming, Gu, Jianren, Cai, Xiumei, Li, Zonghai
Publicado 2015