Aurora kinase A, a synthetic lethal target for precision cancer medicine

por Mou, Pui Kei, Yang, Eun Ju, Shi, Changxiang, Ren, Guowen, Tao, Shishi, Shim, Joong Sup
Publicado 2021

Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT

por Liu, Yifan, Yang, Eun Ju, Shi, Changxiang, Mou, Pui Kei, Zhang, Baoyuan, Wu, Changjie, Lyu, Junfang, Shim, Joong Sup
Publicado 2020

Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics

por Lyu, Junfang, Yang, Eun Ju, Zhang, Baoyuan, Wu, Changjie, Pardeshi, Lakhansing, Shi, Changxiang, Mou, Pui Kei, Liu, Yifan, Tan, Kaeling, Shim, Joong Sup
Publicado 2020

BRCA1 Insufficiency Induces a Hypersialylated Acidic Tumor Microenvironment That Promotes Metastasis and Immunotherapy Resistance

por Shu, Xiaodong, Li, Jianjie, Chan, Un In, Su, Sek Man, Shi, Changxiang, Zhang, Xin, An, Tingting, Xu, Jun, Mo, Lihua, Liu, Jianlin, Wang, Yuqing, Li, Xiaoling, Deng, Min, Lei, Josh Haipeng, Wang, Chunfei, Tian, Hao, Heng, Sun, Shim, Joong Sup, Zhang, Xuanjun, Dai, Yunlu, Yao, Zhicheng, Kuang, Xiaying, Lin, Ying, Deng, Chu-Xia, Xu, Xiaoling
Publicado 2023