Targeting Ras with protein engineering

por Tomazini, Atilio, Shifman, Julia M.
Publicado 2023

Tradeoff Between Stability and Multispecificity in the Design of Promiscuous Proteins

por Fromer, Menachem, Shifman, Julia M.
Publicado 2009

How Structure Defines Affinity in Protein-Protein Interactions

por Erijman, Ariel, Rosenthal, Eran, Shifman, Julia M.
Publicado 2014

Generating quantitative binding landscapes through fractional binding selections combined with deep sequencing and data normalization

por Heyne, Michael, Papo, Niv, Shifman, Julia M.
Publicado 2020

Cold spots are universal in protein–protein interactions

por Gurusinghe, Sagara N.S., Oppenheimer, Ben, Shifman, Julia M.
Publicado 2022

Computational design of Matrix Metalloprotenaise-9 (MMP-9) resistant to autocleavage

por Bonadio, Alessandro, Oguche, Solomon, Lavy, Tali, Kleifeld, Oded, Shifman, Julia
Publicado 2023

Computational design of Matrix Metalloproteinase-9 (MMP-9) resistant to auto-cleavage

por Bonadio, Alessandro, Oguche, Solomon, Lavy, Tali, Kleifeld, Oded, Shifman, Julia
Publicado 2023

Affinity- and Specificity-Enhancing Mutations Are Frequent in Multispecific Interactions between TIMP2 and MMPs

por Sharabi, Oz, Shirian, Jason, Grossman, Moran, Lebendiker, Mario, Sagi, Irit, Shifman, Julia
Publicado 2014

Climbing Up and Down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein–Protein Complexes

por Heyne, Michael, Shirian, Jason, Cohen, Itay, Peleg, Yoav, Radisky, Evette S., Papo, Niv, Shifman, Julia M.
Publicado 2021

Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anticancer activities in lung adenocarcinoma

por Singh, Anamika, Erijman, Ariel, Noronha, Ashish, Kumar, Hemant, Peleg, Yoav, Yarden, Yosef, Shifman, Julia M.
Publicado 2021

Design, expression and characterization of mutants of fasciculin optimized for interaction with its target, acetylcholinesterase

por Sharabi, Oz, Peleg, Yoav, Mashiach, Efrat, Vardy, Eyal, Ashani, Yacov, Silman, Israel, Sussman, Joel L., Shifman, Julia M.
Publicado 2009

A KLK4 proteinase substrate capture approach to antagonize PAR1

por Rabinovitch, Eitan, Mihara, Koishiro, Sananes, Amiram, Zaretsky, Marianna, Heyne, Michael, Shifman, Julia, Aharoni, Amir, Hollenberg, Morley D., Papo, Niv
Publicado 2021