Insights on the use of biosimilars in the treatment of inflammatory bowel disease

por Zheng, Michael K, Shih, David Q, Chen, Gary C
Publicado 2017

Inflammatory Bowel Disease Associated Colorectal Neoplasia

por Vu, Michelle, Chang, Jyh-Yau, Chen, Jeremy, Shih, David Q.
Publicado 2012

Mesenchymal stem cell transplantation improves chronic colitis-associated complications through inhibiting the activity of toll-like receptor-4 in mice

por Niu, Guo chao, Liu, Lei, Zheng, Libo, Zhang, Hong, Shih, David Q., Zhang, Xiaolan
Publicado 2018

Systemic Activation of TLR3-Dependent TRIF Signaling Confers Host Defense against Gram-Negative Bacteria in the Intestine

por Ruiz, Jose, Kanagavelu, Saravana, Flores, Claudia, Romero, Laura, Riveron, Reldy, Shih, David Q., Fukata, Masayuki
Publicado 2016

High circulating elafin levels are associated with Crohn’s disease-associated intestinal strictures

por Wang, Jiani, Ortiz, Christina, Fontenot, Lindsey, Xie, Ying, Ho, Wendy, Mattai, S. Anjani, Shih, David Q., Koon, Hon Wai
Publicado 2020

Protective role of 1,25(OH)(2)vitamin D(3) in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice

por Zhao, Hongwei, Zhang, Hong, Wu, Hui, Li, Hui, Liu, Lei, Guo, Jian, Li, Chenyang, Shih, David Q, Zhang, Xiaolan
Publicado 2012

Mesenteric Adipose-derived Stromal Cells From Crohn’s Disease Patients Induce Protective Effects in Colonic Epithelial Cells and Mice With Colitis

por Hoffman, Jill M., Sideri, Aristea, Ruiz, Jonathan J., Stavrakis, Dimitris, Shih, David Q., Turner, Jerrold R., Pothoulakis, Charalabos, Karagiannides, Iordanes
Publicado 2018

TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization

por Luo, Yuxin, Guo, Jinbo, Jia, Wenxiu, Wu, Mengyao, Yin, Fengrong, Niu, Guochao, Shih, David Q., Targan, Stephan R., Zhang, Xiaolan
Publicado 2021

Substance P Mediates Proinflammatory Cytokine Release From Mesenteric Adipocytes in Inflammatory Bowel Disease Patients

por Sideri, Aristea, Bakirtzi, Kyriaki, Shih, David Q., Koon, Hon Wai, Fleshner, Phillip, Arsenescu, Razvan, Arsenescu, Violeta, Turner, Jerrold R., Karagiannides, Iordanes, Pothoulakis, Charalabos
Publicado 2015

Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice

por Wang, Jiani, Ortiz, Christina, Fontenot, Lindsey, Mukhopadhyay, Riya, Xie, Ying, Law, Ivy Ka Man, Shih, David Q., Mattai, S. Anjani, Li, Zhaoping, Koon, Hon Wai
Publicado 2020

Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis

por Wenxiu, Jia, Mingyue, Yang, Fei, Han, Yuxin, Luo, Mengyao, Wu, Chenyang, Li, Jia, Song, Hong, Zhang, Shih, David Q., Targan, Stephan R., Xiaolan, Zhang
Publicado 2021

Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis

por Shih, David Q, Zheng, Libo, Zhang, Xiaolan, Zhang, Hong, Kanazawa, Yoshitake, Ichikawa, Ryan, Wallace, Kori L, Chen, Jeremy, Pothoulakis, Charalabos, Koon, Hon W, Targan, Stephan R
Publicado 2014

Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2

por Xie, Ying, Fontenot, Lindsey, Chupina Estrada, Andrea, Nelson, Becca, Wang, Jiani, Shih, David Q., Ho, Wendy, Mattai, S. Anjani, Rieder, Florian, Jensen, Dane D., Bunnett, Nigel W., Koon, Hon Wai
Publicado 2022

Constitutive TL1A (TNFSF15) Expression on Lymphoid or Myeloid Cells Leads to Mild Intestinal Inflammation and Fibrosis

por Shih, David Q., Barrett, Robert, Zhang, Xiaolan, Yeager, Nicole, Koon, Hon Wai, Phaosawasdi, Piangwarin, Song, Yahui, Ko, Brian, Wong, Michelle H., Michelsen, Kathrin S., Martins, Gislaine, Pothoulakis, Charalabos, Targan, Stephan R.
Publicado 2011

Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo

por Jacob, Noam, Kumagai, Kotaro, Abraham, Jay P., Shimodaira, Yosuke, Ye, Yuefang, Luu, Justin, Blackwood, Anna Y., Castanon, Sofi L., Stamps, Dalton T., Thomas, Lisa S., Gonsky, Rivkah, Shih, David Q., Michelsen, Kathrin S., Targan, Stephan R.
Publicado 2020

Inflammation independent TL1A-mediated Intestinal Fibrosis is Dependent on the Gut Microbiome

por Jacob, Noam, Jacobs, Jonathan P., Kumagai, Kotaro, Ha, Connie W.Y., Kanazawa, Yoshitake, Lagishetty, Venu, Altmayer, Katherine, Hamill, Ariel M., Von Arx, Aimee, Sartor, R. Balfour, Devkota, Suzanne, Braun, Jonathan, Michelsen, Kathrin S., Targan, Stephan R, Shih, David Q
Publicado 2018

DR3 Regulates Intestinal Epithelial Homeostasis and Regeneration After Intestinal Barrier Injury

por Shimodaira, Yosuke, More, Shyam K., Hamade, Hussein, Blackwood, Anna Y., Abraham, Jay P., Thomas, Lisa S., Miller, Jordan H., Stamps, Dalton T., Castanon, Sofi L., Jacob, Noam, Ha, Connie W.Y., Devkota, Suzanne, Shih, David Q., Targan, Stephan R., Michelsen, Kathrin S.
Publicado 2023

CSA13 inhibits colitis-associated intestinal fibrosis via a formyl peptide receptor like-1 mediated HMG-CoA reductase pathway

por Xu, Chunlan, Ghali, Sally, Wang, Jiani, Shih, David Q., Ortiz, Christina, Mussatto, Caroline C., Lee, Elaine C., Tran, Diana H., Jacobs, Jonathan P., Lagishetty, Venu, Fleshner, Phillip, Robbins, Lori, Vu, Michelle, Hing, Tressia C., McGovern, Dermot P. B, Koon, Hon Wai
Publicado 2017

Antifibrogenic Effects of the Antimicrobial Peptide Cathelicidin in Murine Colitis-Associated Fibrosis

por Yoo, Jun Hwan, Ho, Samantha, Tran, Deanna Hoang-Yen, Cheng, Michelle, Bakirtzi, Kyriaki, Kubota, Yuzu, Ichikawa, Ryan, Su, Bowei, Tran, Diana Hoang-Ngoc, Hing, Tressia C., Chang, Irene, Shih, David Q., Issacson, Richard E., Gallo, Richard L., Fiocchi, Claudio, Pothoulakis, Charalabos, Koon, Hon Wai
Publicado 2014

Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis

por Tschurtschenthaler, Markus, Adolph, Timon E., Ashcroft, Jonathan W., Niederreiter, Lukas, Bharti, Richa, Saveljeva, Svetlana, Bhattacharyya, Joya, Flak, Magdalena B., Shih, David Q., Fuhler, Gwenny M., Parkes, Miles, Kohno, Kenji, Iwawaki, Takao, Janneke van der Woude, C., Harding, Heather P., Smith, Andrew M., Peppelenbosch, Maikel P., Targan, Stephan R., Ron, David, Rosenstiel, Philip, Blumberg, Richard S., Kaser, Arthur
Publicado 2017