Mechanistic Systems Modeling to Improve Understanding and Prediction of Cardiotoxicity Caused by Targeted Cancer Therapeutics

por Shim, Jaehee V., Chun, Bryan, van Hasselt, Johan G. C., Birtwistle, Marc R., Saucerman, Jeffrey J., Sobie, Eric A.
Publicado 2017

Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors

por Shim, Jaehee V., Xiong, Yuguang, Dhanan, Priyanka, Dariolli, Rafael, Azeloglu, Evren U., Hu, Bin, Jayaraman, Gomathi, Schaniel, Christoph, Birtwistle, Marc R., Iyengar, Ravi, Dubois, Nicole C., Sobie, Eric A.
Publicado 2023

RNase III nucleases from diverse kingdoms serve as antiviral effectors

por Aguado, Lauren C., Schmid, Sonja, May, Jared, Sabin, Leah R., Panis, Maryline, Blanco-Melo, Daniel, Shim, Jaehee V., Sachs, David, Cherry, Sara, Simon, Anne E., Levraud, Jean-Pierre, tenOever, Benjamin R.
Publicado 2017

Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity

por van Hasselt, J. G. Coen, Rahman, Rayees, Hansen, Jens, Stern, Alan, Shim, Jaehee V., Xiong, Yuguang, Pickard, Amanda, Jayaraman, Gomathi, Hu, Bin, Mahajan, Milind, Gallo, James M., Goldfarb, Joseph, Sobie, Eric A., Birtwistle, Marc R., Schlessinger, Avner, Azeloglu, Evren U., Iyengar, Ravi
Publicado 2020