Selenium-Based S-Adenosylmethionine Analog Reveals the Mammalian Seven-Beta-Strand Methyltransferase METTL10 to Be an EF1A1 Lysine Methyltransferase

por Shimazu, Tadahiro, Barjau, Joaquin, Sohtome, Yoshihiro, Sodeoka, Mikiko, Shinkai, Yoichi
Publicado 2014

SIRT1 and SIRT3 Deacetylate Homologous Substrates: AceCS1,2 and HMGCS1,2

por Hirschey, Matthew D., Shimazu, Tadahiro, Capra, John A., Pollard, Katherine S., Verdin, Eric
Publicado 2011

Mammalian HEMK1 methylates glutamine residue of the GGQ motif of mitochondrial release factors

por Fang, Qi, Kimura, Yusuke, Shimazu, Tadahiro, Suzuki, Takehiro, Yamada, Ayumi, Dohmae, Naoshi, Iwasaki, Shintaro, Shinkai, Yoichi
Publicado 2022

Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8

por Tsusaka, Takeshi, Kikuchi, Masaki, Shimazu, Tadahiro, Suzuki, Takehiro, Sohtome, Yoshihiro, Akakabe, Mai, Sodeoka, Mikiko, Dohmae, Naoshi, Umehara, Takashi, Shinkai, Yoichi
Publicado 2018

Role of METTL20 in regulating β-oxidation and heat production in mice under fasting or ketogenic conditions

por Shimazu, Tadahiro, Furuse, Tamio, Balan, Shabeesh, Yamada, Ikuko, Okuno, Shuzo, Iwanari, Hiroko, Suzuki, Takehiro, Hamakubo, Takao, Dohmae, Naoshi, Yoshikawa, Takeo, Wakana, Shigeharu, Shinkai, Yoichi
Publicado 2018

METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance

por Matsuura-Suzuki, Eriko, Shimazu, Tadahiro, Takahashi, Mari, Kotoshiba, Kaoru, Suzuki, Takehiro, Kashiwagi, Kazuhiro, Sohtome, Yoshihiro, Akakabe, Mai, Sodeoka, Mikiko, Dohmae, Naoshi, Ito, Takuhiro, Shinkai, Yoichi, Iwasaki, Shintaro
Publicado 2022

Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity

por Shirakawa, Kotaro, Wang, Lan, Man, Na, Maksimoska, Jasna, Sorum, Alexander W, Lim, Hyung W, Lee, Intelly S, Shimazu, Tadahiro, Newman, John C, Schröder, Sebastian, Ott, Melanie, Marmorstein, Ronen, Meier, Jordan, Nimer, Stephen, Verdin, Eric
Publicado 2016

Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B

por Cho, Hyun-Soo, Shimazu, Tadahiro, Toyokawa, Gouji, Daigo, Yataro, Maehara, Yoshihiko, Hayami, Shinya, Ito, Akihiro, Masuda, Ken, Ikawa, Noriko, Field, Helen I., Tsuchiya, Eiju, Ohnuma, Shin-ichi, Ponder, Bruce A.J., Yoshida, Minoru, Nakamura, Yusuke, Hamamoto, Ryuji
Publicado 2012

SIRT3 regulates fatty acid oxidation via reversible enzyme deacetylation

por Hirschey, Matthew D., Shimazu, Tadahiro, Goetzman, Eric, Jing, Enxuan, Schwer, Bjoern, Lombard, David B., Grueter, Carrie A., Harris, Charles, Biddinger, Sudha, Ilkayeva, Olga R., Stevens, Robert D., Li, Yu, Saha, Asish K., Ruderman, Neil B., Bain, James R., Newgard, Christopher B., Farese, Robert V., Alt, Frederick W., Kahn, C. Ronald, Verdin, Eric
Publicado 2010

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

por Davydova, Erna, Shimazu, Tadahiro, Schuhmacher, Maren Kirstin, Jakobsson, Magnus E., Willemen, Hanneke L. D. M., Liu, Tongri, Moen, Anders, Ho, Angela Y. Y., Małecki, Jędrzej, Schroer, Lisa, Pinto, Rita, Suzuki, Takehiro, Grønsberg, Ida A., Sohtome, Yoshihiro, Akakabe, Mai, Weirich, Sara, Kikuchi, Masaki, Olsen, Jesper V., Dohmae, Naoshi, Umehara, Takashi, Sodeoka, Mikiko, Siino, Valentina, McDonough, Michael A., Eijkelkamp, Niels, Schofield, Christopher J., Jeltsch, Albert, Shinkai, Yoichi, Falnes, Pål Ø.
Publicado 2021