Peptide-Based Vaccines for Hepatocellular Carcinoma: A Review of Recent Advances

por Charneau, Jimmy, Suzuki, Toshihiro, Shimomura, Manami, Fujinami, Norihiro, Nakatsura, Tetsuya
Publicado 2021

Time-lapse imaging assay using the BioStation CT: A sensitive drug-screening method for three-dimensional cell culture

por Sakamoto, Ruriko, Rahman, M Mamunur, Shimomura, Manami, Itoh, Manabu, Nakatsura, Tetsuya
Publicado 2015

Programmed death-1 blockade enhances the antitumor effects of peptide vaccine-induced peptide-specific cytotoxic T lymphocytes

por SAWADA, YU, YOSHIKAWA, TOSHIAKI, SHIMOMURA, MANAMI, IWAMA, TATSUAKI, ENDO, ITARU, NAKATSURA, TETSUYA
Publicado 2014

Identification of an H2-K(b) or H2-D(b) restricted and glypican-3-derived cytotoxic T-lymphocyte epitope peptide

por IWAMA, TATSUAKI, HORIE, KAZUTAKA, YOSHIKAWA, TOSHIAKI, NOBUOKA, DAISUKE, SHIMOMURA, MANAMI, SAWADA, YU, NAKATSURA, TETSUYA
Publicado 2013

Analysis of cytotoxic T lymphocytes from a patient with hepatocellular carcinoma who showed a clinical response to vaccination with a glypican-3-derived peptide

por TADA, YOSHITAKA, YOSHIKAWA, TOSHIAKI, SHIMOMURA, MANAMI, SAWADA, YU, SAKAI, MAYUKO, SHIRAKAWA, HIROFUMI, NOBUOKA, DAISUKE, NAKATSURA, TETSUYA
Publicado 201

A peptide antigen derived from EGFR T790M is immunogenic in non-small cell lung cancer

por OFUJI, KAZUYA, TADA, YOSHITAKA, YOSHIKAWA, TOSHIAKI, SHIMOMURA, MANAMI, YOSHIMURA, MAYUKO, SAITO, KEIGO, NAKAMOTO, YASUNARI, NAKATSURA, TETSUYA
Publicado 2014

Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model

por Fujinami, Norihiro, Yoshikawa, Toshiaki, Sawada, Yu, Shimomura, Manami, Iwama, Tatsuaki, Sugai, Shiori, Kitano, Shigehisa, Uemura, Yasushi, Nakatsura, Tetsuya
Publicado 2016

Higher human lymphocyte antigen class I expression in early‐stage cancer cells leads to high sensitivity for cytotoxic T lymphocytes

por Akazawa, Yu, Nobuoka, Daisuke, Takahashi, Mari, Yoshikawa, Toshiaki, Shimomura, Manami, Mizuno, Shoichi, Fujiwara, Toshiyoshi, Nakamoto, Yasunari, Nakatsura, Tetsuya
Publicado 2019

Efficacy of immunotherapy targeting the neoantigen derived from epidermal growth factor receptor T790M/C797S mutation in non–small cell lung cancer

por Akazawa, Yu, Saito, Yuki, Yoshikawa, Toshiaki, Saito, Keigo, Nosaka, Kazuto, Shimomura, Manami, Mizuno, Shoichi, Nakamoto, Yasunari, Nakatsura, Tetsuya
Publicado 2020

Greater extent of blood‐tumor TCR repertoire overlap is associated with favorable clinical responses to PD‐1 blockade

por Aoki, Hiroyasu, Ueha, Satoshi, Nakamura, Yoshiaki, Shichino, Shigeyuki, Nakajima, Hiromichi, Shimomura, Manami, Sato, Akihiro, Nakatsura, Tetsuya, Yoshino, Takayuki, Matsushima, Kouji
Publicado 2021

Development of antigen‐prediction algorithm for personalized neoantigen vaccine using human leukocyte antigen transgenic mouse

por Charneau, Jimmy, Suzuki, Toshihiro, Shimomura, Manami, Fujinami, Norihiro, Mishima, Yuji, Hiranuka, Kazushi, Watanabe, Noriko, Yamada, Takashi, Nakamura, Norihiro, Nakatsura, Tetsuya
Publicado 2022

Hepatocellular carcinoma cell sensitivity to Vγ9Vδ2 T lymphocyte-mediated killing is increased by zoledronate

por SUGAI, SHIORI, YOSHIKAWA, TOSHIAKI, IWAMA, TATSUAKI, TSUCHIYA, NOBUHIRO, UEDA, NORIHIRO, FUJINAMI, NORIHIRO, SHIMOMURA, MANAMI, ZHANG, RONG, KANEKO, SHIN, UEMURA, YASUSHI, NAKATSURA, TETSUYA
Publicado 2016

Ki67 expression and localization of T cells after neoadjuvant therapies as reliable predictive markers in rectal cancer

por Imaizumi, Ken, Suzuki, Toshihiro, Kojima, Motohiro, Shimomura, Manami, Sakuyama, Naoki, Tsukada, Yuichiro, Sasaki, Takeshi, Nishizawa, Yuji, Taketomi, Akinobu, Ito, Masaaki, Nakatsura, Tetsuya
Publicado 2019

Circulating cancer‐associated extracellular vesicles as early detection and recurrence biomarkers for pancreatic cancer

por Yoshioka, Yusuke, Shimomura, Manami, Saito, Keigo, Ishii, Hideshi, Doki, Yuichiro, Eguchi, Hidetoshi, Nakatsura, Tetsuya, Itoi, Takao, Kuroda, Masahiko, Mori, Masaki, Ochiya, Takahiro
Publicado 2022

Identification of HLA-A2 or HLA-A24-restricted CTL epitopes for potential HSP105-targeted immunotherapy in colorectal cancer

por SAWADA, YU, KOMORI, HIROYUKI, TSUNODA, YOSHIYUKI, SHIMOMURA, MANAMI, TAKAHASHI, MARI, BABA, HIDEO, ITO, MASAAKI, SAITO, NORIO, KUWANO, HIROYUKI, ENDO, ITARU, NISHIMURA, YASUHARU, NAKATSURA, TETSUYA
Publicado 2014

Intratumoral peptide injection enhances tumor cell antigenicity recognized by cytotoxic T lymphocytes: a potential option for improvement in antigen-specific cancer immunotherapy

por Nobuoka, Daisuke, Yoshikawa, Toshiaki, Takahashi, Mari, Iwama, Tatsuaki, Horie, Kazutaka, Shimomura, Manami, Suzuki, Shiro, Sakemura, Noriko, Nakatsugawa, Munehide, Sadamori, Hiroshi, Yagi, Takahito, Fujiwara, Toshiyoshi, Nakatsura, Tetsuya
Publicado 2012

Perioperative plasma glypican-3 level may enable prediction of the risk of recurrence after surgery in patients with stage I hepatocellular carcinoma

por Ofuji, Kazuya, Saito, Keigo, Suzuki, Shiro, Shimomura, Manami, Shirakawa, Hirofumi, Nobuoka, Daisuke, Sawada, Yu, Yoshimura, Mayuko, Tsuchiya, Nobuhiro, Takahashi, Mari, Yoshikawa, Toshiaki, Tada, Yoshitaka, Konishi, Masaru, Takahashi, Shinichiro, Gotohda, Naoto, Nakamoto, Yasunari, Nakatsura, Tetsuya
Publicado 2016

Efficacy of the NCCV Cocktail‐1 vaccine for refractory pediatric solid tumors: A phase I clinical trial

por Akazawa, Yu, Hosono, Ako, Yoshikawa, Toshiaki, Kaneda, Hide, Nitani, Chika, Hara, Junichi, Kinoshita, Yoshiaki, Kohashi, Kenichi, Manabe, Atsushi, Fukutani, Miki, Wakabayashi, Masashi, Sato, Akihiro, Shoda, Kayoko, Shimomura, Manami, Mizuno, Shoichi, Nakamoto, Yasunari, Nakatsura, Tetsuya
Publicado 2019

Phase I study of glypican-3-derived peptide vaccine therapy for patients with refractory pediatric solid tumors

por Tsuchiya, Nobuhiro, Hosono, Ako, Yoshikawa, Toshiaki, Shoda, Kayoko, Nosaka, Kazuto, Shimomura, Manami, Hara, Junichi, Nitani, Chika, Manabe, Atsushi, Yoshihara, Hiroki, Hosoya, Yosuke, Kaneda, Hide, Kinoshita, Yoshiaki, Kohashi, Kenichi, Yoshimura, Kenichi, Fujinami, Norihiro, Saito, Keigo, Mizuno, Shoichi, Nakatsura, Tetsuya
Publicado 2017

First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors

por Shitara, Kohei, Ueha, Satoshi, Shichino, Shigeyuki, Aoki, Hiroyasu, Ogiwara, Haru, Nakatsura, Tetsuya, Suzuki, Toshihiro, Shimomura, Manami, Yoshikawa, Toshiaki, Shoda, Kayoko, Kitano, Shigehisa, Yamashita, Makiko, Nakayama, Takayuki, Sato, Akihiro, Kuroda, Sakiko, Wakabayashi, Masashi, Nomura, Shogo, Yokochi, Shoji, Ito, Satoru, Matsushima, Kouji, Doi, Toshihiko
Publicado 2019