Inflammasome-mediated cell death in response to bacterial pathogens that access the host cell cytosol: lessons from legionella pneumophila

por Casson, Cierra N., Shin, Sunny
Publicado 2013

Yersinia deploys type III-secreted effectors to evade caspase-4 inflammasome activation in human cells

por Zhang, Jenna, Brodsky, Igor E., Shin, Sunny
Publicado 2023

Yersinia Type III-Secreted Effectors Evade the Caspase-4 Inflammasome in Human Cells

por Zhang, Jenna, Brodsky, Igor E., Shin, Sunny
Publicado 2023

TNF and type I IFN induction of the IRG1-itaconate pathway restricts Coxiella burnetii replication within mouse macrophages

por Boyer, Mark A., Fischer, Natasha Lopes, Shin, Sunny
Publicado 2023

Outrunning the Red Queen: bystander activation as a means of outpacing innate immune subversion by intracellular pathogens

por Holmgren, Alicia M, McConkey, Cameron A, Shin, Sunny
Publicado 2017

TNF licenses macrophages to undergo rapid caspase-1, -11, and -8-mediated cell death that restricts Legionella pneumophila infection

por Pollock, Tzvi Y., Vázquez Marrero, Víctor R., Brodsky, Igor E., Shin, Sunny
Publicado 2023

The D0 Domain of KIR3D Acts as a Major Histocompatibility Complex Class I Binding Enhancer

por Khakoo, Salim I., Geller, Ron, Shin, Sunny, Jenkins, Jomaquai A., Parham, Peter
Publicado 2002

Human GBP1 facilitates the rupture of the Legionella-containing vacuole and inflammasome activation

por Bass, Antonia R., Egan, Marisa S., Alexander-Floyd, Jasmine, Lopes Fischer, Natasha, Doerner, Jessica, Shin, Sunny
Publicado 2023

Age-related differences in IL-1 signaling and capsule serotype affect persistence of Streptococcus pneumoniae colonization

por Kuipers, Kirsten, Lokken, Kristen L., Zangari, Tonia, Boyer, Mark A., Shin, Sunny, Weiser, Jeffrey N.
Publicado 2018

Rapid Pathogen-Induced Apoptosis: A Mechanism Used by Dendritic Cells to Limit Intracellular Replication of Legionella pneumophila

por Nogueira, Catarina V., Lindsten, Tullia, Jamieson, Amanda M., Case, Christopher L., Shin, Sunny, Thompson, Craig B., Roy, Craig R.
Publicado 2009

Increased autophagic sequestration in adaptor protein-3 deficient dendritic cells limits inflammasome activity and impairs antibacterial immunity

por Mantegazza, Adriana R., Wynosky-Dolfi, Meghan A., Casson, Cierra N., Lefkovith, Ariel J., Shin, Sunny, Brodsky, Igor E., Marks, Michael S.
Publicado 2017

Type IV Secretion-Dependent Activation of Host MAP Kinases Induces an Increased Proinflammatory Cytokine Response to Legionella pneumophila

por Shin, Sunny, Case, Christopher L., Archer, Kristina A., Nogueira, Catarina V., Kobayashi, Koichi S., Flavell, Richard A., Roy, Craig R., Zamboni, Dario S.
Publicado 2008

TLR priming licenses NAIP inflammasome activation by immunoevasive ligands

por Grayczyk, James P., Egan, Marisa S., Liu, Luying, Aunins, Emily, Wynosky-Dolfi, Meghan A., Canna, Scott, Minn, Andy J., Shin, Sunny, Brodsky, Igor E.
Publicado 2023

Human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella type III secretion system activities to restrict intracellular bacterial replication

por Naseer, Nawar, Egan, Marisa S., Reyes Ruiz, Valeria M., Scott, William P., Hunter, Emma N., Demissie, Tabitha, Rauch, Isabella, Brodsky, Igor E., Shin, Sunny
Publicado 2022

The tetrapeptide sequence of IL-1β regulates its recruitment and activation by inflammatory caspases

por Exconde, Patrick M., Hernandez-Chavez, Claudia, Bray, Mark B., Lopez, Jan L., Srivastava, Tamanna, Egan, Marisa S., Zhang, Jenna, Shin, Sunny, Discher, Bohdana M., Taabazuing, Cornelius Y.
Publicado 2023

Neutrophils and Ly6C(hi) monocytes collaborate in generating an optimal cytokine response that protects against pulmonary Legionella pneumophila infection

por Casson, Cierra N., Doerner, Jessica L., Copenhaver, Alan M., Ramirez, Jasmine, Holmgren, Alicia M., Boyer, Mark A., Siddarthan, Ingharan J., Rouhanifard, Sara H., Raj, Arjun, Shin, Sunny
Publicado 2017

Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages

por Egan, Marisa S., O’Rourke, Emily A., Mageswaran, Shrawan Kumar, Zuo, Biao, Martynyuk, Inna, Demissie, Tabitha, Hunter, Emma N., Bass, Antonia R., Chang, Yi-Wei, Brodsky, Igor E., Shin, Sunny
Publicado 2023

Caspase-11 Activation in Response to Bacterial Secretion Systems that Access the Host Cytosol

por Casson, Cierra N., Copenhaver, Alan M., Zwack, Erin E., Nguyen, Hieu T., Strowig, Till, Javdan, Bahar, Bradley, William P., Fung, Thomas C., Flavell, Richard A., Brodsky, Igor E., Shin, Sunny
Publicado 2013

A TNF-IL-1 circuit controls Yersinia within intestinal granulomas

por Matsuda, Rina, Sorobetea, Daniel, Zhang, Jenna, Peterson, Stefan T., Grayczyk, James P., Herrmann, Beatrice, Yost, Winslow, O’Neill, Rosemary, Bohrer, Andrea C., Lanza, Matthew, Assenmacher, Charles-Antoine, Mayer-Barber, Katrin D., Shin, Sunny, Brodsky, Igor E.
Publicado 2023