Prediction of pharmacokinetics and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin

por Park, Min-Ho, Shin, Seok-Ho, Byeon, Jin-Ju, Lee, Gwan-Ho, Yu, Byung-Yong, Shin, Young G.
Publicado 2017

Pharmacokinetic and Metabolism Studies of Monomethyl Auristatin F via Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry

por Park, Min-Ho, Lee, Byeong ill, Byeon, Jin-Ju, Shin, Seok-Ho, Choi, Jangmi, Park, Yuri, Shin, Young G.
Publicado 2019

Profiling and Identification of Omeprazole Metabolites in Mouse Brain and Plasma by Isotope Ratio-Monitoring Liquid Chromatography-Mass Spectrometric Method

por Shin, Seok-Ho, Park, Yuri, Park, Min-Ho, Byeon, Jin-Ju, Lee, Byeong ill, Choi, Jangmi, Shin, Young G.
Publicado 2020

Quantification and Metabolite Identification of Sulfasalazine in Mouse Brain and Plasma Using Quadrupole-Time-of-Flight Mass Spectrometry

por Choi, Jangmi, Park, Min-Ho, Shin, Seok-Ho, Byeon, Jin-Ju, Lee, Byeong ill, Park, Yuri, Shin, Young G.
Publicado 2021

Opportunities in low-level radiocarbon microtracing: applications and new technology

por Vuong, Le Thuy, Song, Qi, Lee, Hee Joo, Roffel, Ad F, Shin, Seok-Ho, Shin, Young G, Dueker, Stephen R
Publicado 2015

Quantitative Analysis of Daporinad (FK866) and Its In Vitro and In Vivo Metabolite Identification Using Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry

por Park, Minjae, Lee, Byeong Ill, Choi, Jangmi, Park, Yuri, Park, Seo-Jin, Lim, Jeong-Hyeon, Lee, Jiyu, Shin, Young G.
Publicado 2022

Qualification and Application of a Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometric Method for the Determination of Adalimumab in Rat Plasma

por Park, Yuri, Kim, Nahye, Choi, Jangmi, Park, Min-Ho, Lee, Byeong ill, Shin, Seok-Ho, Byeon, Jin-Ju, Shin, Young G.
Publicado 2018

Analysis of Vipadenant and Its In Vitro and In Vivo Metabolites via Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry

por Shin, Seok-Ho, Park, Min-Ho, Byeon, Jin-Ju, Lee, Byeong ill, Park, Yuri, Kim, Nahye, Choi, Jangmi, Shin, Young G.
Publicado 2018

Quantitative Analysis of Tozadenant Using Liquid Chromatography-Mass Spectrometric Method in Rat Plasma and Its Human Pharmacokinetics Prediction Using Physiologically Based Pharma...

por Lee, Byeong ill, Park, Min-Ho, Shin, Seok-Ho, Byeon, Jin-Ju, Park, Yuri, Kim, Nahye, Choi, Jangmi, Shin, Young G.
Publicado 2019

Effect of Ticagrelor, a Cytochrome P450 3A4 Inhibitor, on the Pharmacokinetics of Tadalafil in Rats

por Na, Young-Guk, Byeon, Jin-Ju, Huh, Hyun Wook, Kim, Min-Ki, Shin, Young G., Lee, Hong-Ki, Cho, Cheong-Weon
Publicado 2019

Evaluation of In Vivo Prepared Albumin-Drug Conjugate Using Immunoprecipitation Linked LC-MS Assay and Its Application to Mouse Pharmacokinetic Study

por Lim, Jeong-Hyeon, Park, Minjae, Park, Yuri, Park, Seo-Jin, Lee, Jiyu, Hwang, Sangsoo, Lee, Jeongmin, Lee, Yujin, Jo, Eunjeong, Shin, Young G.
Publicado 2023

Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

por Park, Gab-jin, Bae, Soo Hyeon, Park, Wan-Su, Han, Seunghoon, Park, Min-Ho, Shin, Seok-Ho, Shin, Young G, Yim, Dong-Seok
Publicado 2017

Quantification of an Antibody-Conjugated Drug in Fat Plasma by an Affinity Capture LC-MS/MS Method for a Novel Prenyl Transferase-Mediated Site-Specific Antibody–Drug Conjugate

por Lee, Byeong ill, Park, Min-Ho, Byeon, Jin-Ju, Shin, Seok-Ho, Choi, Jangmi, Park, Yuri, Park, Yun-Hee, Chae, Jeiwook, Shin, Young G.
Publicado 2020

Investigation of In Vitro and In Vivo Metabolism of α-Amanitin in Rats Using Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometric Method

por Lee, Jiyu, Lee, Byeong ill, Choi, Jangmi, Park, Yuri, Park, Seo-Jin, Park, Minjae, Lim, Jeong-Hyeon, Hwang, Sangsoo, Lee, Jeong-Min, Shin, Young G.
Publicado 2022

Assessments of the In Vitro and In Vivo Linker Stability and Catabolic Fate for the Ortho Hydroxy-Protected Aryl Sulfate Linker by Immuno-Affinity Capture Liquid Chromatography Qua...

por Lee, Byeong ill, Park, Seo-jin, Park, Yuri, Shin, Seok-Ho, Choi, Jang-mi, Park, Min-jae, Lim, Jeong-hyeon, Kim, Sun Young, Lee, Hyangsook, Shin, Young G.
Publicado 2021

Qualification and application of liquid chromatography-quadrupole time-of-flight mass spectrometric method for the determination of carisbamate in rat plasma and prediction of its...

por Lee, Byeong ill, Lim, Jeong-hyeon, Park, Min-Ho, Shin, Seok-Ho, Byeon, Jin-Ju, Choi, Jang-mi, Park, Seo-jin, Park, Min-jae, Park, Yuri, Shin, Young G.
Publicado 2020

Assessment of Pharmacokinetics and Metabolism Profiles of SCH 58261 in Rats Using Liquid Chromatography–Mass Spectrometric Method

por Park, Yuri, Park, Min-Ho, Byeon, Jin-Ju, Shin, Seok-Ho, Lee, Byeong ill, Choi, Jang-mi, Kim, Nahye, Park, Seo-jin, Park, Min-jae, Lim, Jeong-hyeon, Shin, Young G.
Publicado 2020

In Vitro, In Silico, and In Vivo Assessments of Pharmacokinetic Properties of ZM241385

por Byeon, Jin-Ju, Park, Min-Ho, Shin, Seok-Ho, Park, Yuri, Lee, Byeong ill, Choi, Jang-mi, Kim, Nahye, Park, Seo-jin, Park, Min-jae, Lim, Jeong-hyeon, Na, Young-Guk, Shin, Young G.
Publicado 2020

A Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometric Assay for the Quantification of Fabry Disease Biomarker Globotriaosylceramide (GB3) in Fabry Model Mouse

por Shin, Seok-Ho, Park, Min-Ho, Byeon, Jin-Ju, Lee, Byeong ill, Park, Yuri, Ko, Ah-ra, Seong, Mi-ran, Lee, Soyeon, Kim, Mi Ra, Seo, Jinwook, Jung, Myung Eun, Jin, Dong-Kyu, Shin, Young G.
Publicado 2018

First-in-human study of IM156, a novel potent biguanide oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced solid tumors

por Janku, Filip, Beom, Seung-Hoon, Moon, Yong Wha, Kim, Tae Won, Shin, Young G., Yim, Dong-Seok, Kim, Gun Min, Kim, Hyo Song, Kim, Sun Young, Cheong, Jae-Ho, Lee, Young Woo, Geiger, Barb, Yoo, Sanghee, Thurston, Archie, Welsch, Dean, Rudoltz, Marc S., Rha, Sun Young
Publicado 2022