Targeting ACE2-RBD interaction as a platform for COVID19 therapeutics: Development and drug repurposing screen of an AlphaLISA proximity assay

por Hanson, Quinlin M., Wilson, Kelli M., Shen, Min, Itkin, Zina, Eastman, Richard T., Shinn, Paul, Hall, Matthew D.
Publicado 2020

Targeting ACE2–RBD Interaction as a Platform for COVID-19 Therapeutics: Development and Drug-Repurposing Screen of an AlphaLISA Proximity Assay

por Hanson, Quinlin M., Wilson, Kelli M., Shen, Min, Itkin, Zina, Eastman, Richard T., Shinn, Paul, Hall, Matthew D.
Publicado 2020

Retro Drug Design: From Target Properties to Molecular Structures

por Wang, Yuhong, Michael, Sam, Huang, Ruili, Zhao, Jinghua, Recabo, Katlin, Bougie, Danielle, Shu, Qiang, Shinn, Paul, Sun, Hongmao
Publicado 2021

Phenotype-driven chemical screening in zebrafish for compounds that inhibit collective cell migration identifies multiple pathways potentially involved in metastatic invasion

por Gallardo, Viviana E., Varshney, Gaurav K., Lee, Minnkyong, Bupp, Sujata, Xu, Lisha, Shinn, Paul, Crawford, Nigel P., Inglese, James, Burgess, Shawn M.
Publicado 2015

Retroviral DNA Integration: ASLV, HIV, and MLV Show Distinct Target Site Preferences

por Mitchell, Rick S, Beitzel, Brett F, Schroder, Astrid R. W, Shinn, Paul, Chen, Huaming, Berry, Charles C, Ecker, Joseph R, Bushman, Frederic D
Publicado 2004

Novel lead structures with both Plasmodium falciparum gametocytocidal and asexual blood stage activity identified from high throughput compound screening

por Sun, Wei, Huang, Xiuli, Li, Hao, Tawa, Gregory, Fisher, Ethan, Tanaka, Takeshi Q., Shinn, Paul, Huang, Wenwei, Williamson, Kim C., Zheng, Wei
Publicado 2017

Retro Drug Design: From Target Properties to Molecular Structures

por Wang, Yuhong, Michael, Sam, Yang, Shyh-Ming, Huang, Ruili, Cruz-Gutierrez, Kennie, Zhang, Yaqing, Zhao, Jinghua, Xia, Menghang, Shinn, Paul, Sun, Hongmao
Publicado 2022

A Homogenous Luminescence Assay Reveals Novel Inhibitors for Giardia Lamblia Carbamate Kinase

por Chen, Catherine Z, Southall, Noel, Galkin, Andrey, Lim, Kap, Marugan, Juan J, Kulakova, Liudmila, Shinn, Paul, van Leer, Danielle, Zheng, Wei, Herzberg, Osnat
Publicado 2012

Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening

por Zhu, Wei, Xu, Miao, Chen, Catherine Z., Guo, Hui, Shen, Min, Hu, Xin, Shinn, Paul, Klumpp-Thomas, Carleen, Michael, Samuel G., Zheng, Wei
Publicado 2020

Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-Throughput Screening

por Zhu, Wei, Xu, Miao, Chen, Catherine Z., Guo, Hui, Shen, Min, Hu, Xin, Shinn, Paul, Klumpp-Thomas, Carleen, Michael, Samuel G., Zheng, Wei
Publicado 2020

Rapid antimicrobial susceptibility test for identification of new therapeutics and drug combinations against multidrug-resistant bacteria

por Sun, Wei, Weingarten, Rebecca A, Xu, Miao, Southall, Noel, Dai, Sheng, Shinn, Paul, Sanderson, Philip E, Williamson, Peter R, Frank, Karen M, Zheng, Wei
Publicado 2016

Rapid Identification of Antifungal Compounds against Exserohilum rostratum Using High Throughput Drug Repurposing Screens

por Sun, Wei, Park, Yoon-Dong, Sugui, Janyce A., Fothergill, Annette, Southall, Noel, Shinn, Paul, McKew, John C., Kwon-Chung, Kyung J., Zheng, Wei, Williamson, Peter R.
Publicado 2013

Correction: Rapid Identification of Antifungal Compounds against Exserohilum rostratum Using High Throughput Drug Repurposing Screens

por Sun, Wei, Park, Yoon-Dong, Sugui, Janyce A., Fothergill, Annette, Southall, Noel, Shinn, Paul, McKew, John C., Kwon-Chung, Kyung J., Zheng, Wei, Williamson, Peter R.
Publicado 2013

Correction: Rapid Identification of Antifungal Compounds against Exserohilum rostratum Using High Throughput Drug Repurposing Screens

por Sun, Wei, Park, Yoon-Dong, Sugui, Janyce A., Fothergill, Annette, Southall, Noel, Shinn, Paul, McKew, John C., Kwon-Chung, Kyung J., Zheng, Wei, Williamson, Peter R.
Publicado 2013

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

por Kouznetsova, Jennifer, Sun, Wei, Martínez-Romero, Carles, Tawa, Gregory, Shinn, Paul, Chen, Catherine Z, Schimmer, Aaron, Sanderson, Philip, McKew, John C, Zheng, Wei, García-Sastre, Adolfo
Publicado 2014

Discovery of TMPRSS2 inhibitors from virtual screening

por Hu, Xin, Shrimp, Jonathan H., Guo, Hui, Xu, Miao, Chen, Catherine Z., Zhu, Wei, Zakharov, Alexey, Jain, Sankalp, Shinn, Paul, Simeonov, Anton, Hall, Matthew D., Shen, Min
Publicado 2021

Discovery of TMPRSS2 Inhibitors from Virtual Screening as a Potential Treatment of COVID-19

por Hu, Xin, Shrimp, Jonathan H., Guo, Hui, Xu, Miao, Chen, Catherine Z., Zhu, Wei, Zakharov, Alexey V., Jain, Sankalp, Shinn, Paul, Simeonov, Anton, Hall, Matthew D., Shen, Min
Publicado 2021

Discovery of Small Molecule Entry Inhibitors Targeting the Fusion Peptide of SARS-CoV-2 Spike Protein

por Hu, Xin, Chen, Catherine Z., Xu, Miao, Hu, Zongyi, Guo, Hui, Itkin, Zina, Shinn, Paul, Ivin, Parker, Leek, Madeleine, Liang, T. Jake, Shen, Min, Zheng, Wei, Hall, Matthew D.
Publicado 2021

Large-scale pharmacological profiling of 3D tumor models of cancer cells

por Mathews Griner, Lesley A, Zhang, Xiaohu, Guha, Rajarshi, McKnight, Crystal, Goldlust, Ian S, Lal-Nag, Madhu, Wilson, Kelli, Michael, Sam, Titus, Steve, Shinn, Paul, Thomas, Craig J, Ferrer, Marc
Publicado 2016

Discovery of Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 In Vitro

por Bobrowski, Tesia, Chen, Lu, Eastman, Richard T., Itkin, Zina, Shinn, Paul, Chen, Catherine, Guo, Hui, Zheng, Wei, Michael, Sam, Simeonov, Anton, Hall, Matthew D., Zakharov, Alexey V., Muratov, Eugene N.
Publicado 2020