Epigenetic Targets in Synovial Sarcoma: A Mini-Review

por Hale, Ryland, Sandakly, Sami, Shipley, Janet, Walters, Zoë
Publicado 2019

Targeting the Insulin-Like Growth Factor Pathway in Rhabdomyosarcomas: Rationale and Future Perspectives

por Martins, Ana Sofia, Olmos, David, Missiaglia, Edoardo, Shipley, Janet
Publicado 2011

The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells

por O’Brien, Eleanor M., Selfe, Joanna L., Martins, Ana Sofia, Walters, Zoë S., Shipley, Janet M.
Publicado 2018

Endosialin expression in soft tissue sarcoma as a potential marker of undifferentiated mesenchymal cells

por Thway, Khin, Robertson, David, Jones, Robin L, Selfe, Joanna, Shipley, Janet, Fisher, Cyril, Isacke, Clare M
Publicado 2016

Hypoxia and its therapeutic possibilities in paediatric cancers

por Bernauer, Carolina, Man, Y. K. Stella, Chisholm, Julia C., Lepicard, Elise Y., Robinson, Simon P., Shipley, Janet M.
Publicado 2020

Polygenic susceptibility to testicular cancer: implications for personalised health care

por Litchfield, Kevin, Mitchell, Jonathan S, Shipley, Janet, Huddart, Robert, Rajpert-De Meyts, Ewa, Skakkebæk, Niels E, Houlston, Richard S, Turnbull, Clare
Publicado 2015

Polygenic susceptibility to testicular cancer: implications for personalised health care

por Litchfield, Kevin, Mitchell, Jonathan S, Shipley, Janet, Huddart, Robert, Rajpert-De Meyts, Ewa, Skakkebæk, Niels E, Houlston, Richard S, Turnbull, Clare
Publicado 2016

MicroRNA and gene co-expression networks characterize biological and clinical behavior of rhabdomyosarcomas

por Missiaglia, Edoardo, Shepherd, Chris J., Aladowicz, Ewa, Olmos, David, Selfe, Joanna, Pierron, Gaëlle, Delattre, Olivier, Walters, Zoe, Shipley, Janet
Publicado 2017

The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma

por Mohamed, Abdalla, Sun, Congshan, De Mello, Vanessa, Selfe, Joanna, Missiaglia, Edoardo, Shipley, Janet, Murray, Graeme I, Zammit, Pete S, Wackerhage, Henning
Publicado 2016

Role for the Histone Demethylase KDM4B in Rhabdomyosarcoma via CDK6 and CCNA2: Compensation by KDM4A and Apoptotic Response of Targeting Both KDM4B and KDM4A

por Walters, Zoë S., Aladowicz, Ewa, Villarejo-Balcells, Barbara, Nugent, Gary, Selfe, Joanna L., Eve, Paul, Blagg, Julian, Rossanese, Olivia, Shipley, Janet
Publicado 2021

Endo180 (MRC2) Antibody–Drug Conjugate for the Treatment of Sarcoma

por Evans, Rachel J., Perkins, Douglas W., Selfe, Joanna, Kelsey, Anna, Birch, Gavin P., Shipley, Janet M., Schipper, Koen, Isacke, Clare M.
Publicado 2023

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas

por Gatz, Susanne A., Aladowicz, Ewa, Casanova, Michela, Chisholm, Julia C., Kearns, Pamela R., Fulda, Simone, Geoerger, Birgit, Schäfer, Beat W., Shipley, Janet M.
Publicado 2019

JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells

por Walters, Zoë S, Villarejo-Balcells, Barbara, Olmos, David, Buist, Thomas WS, Missiaglia, Edoardo, Allen, Rebecca, Al-Lazikani, Bissan, Garrett, Michelle D, Blagg, Julian, Shipley, Janet
Publicado 2013

An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model

por Mensah, Afua, Mulligan, Claire, Linehan, Jackie, Ruf, Sandra, O'Doherty, Aideen, Grygalewicz, Beata, Shipley, Janet, Groet, Juergen, Tybulewicz, Victor, Fisher, Elizabeth, Brandner, Sebastian, Nizetic, Dean
Publicado 2007

Genomic and Epigenetic Changes Drive Aberrant Skeletal Muscle Differentiation in Rhabdomyosarcoma

por Pomella, Silvia, Danielli, Sara G., Alaggio, Rita, Breunis, Willemijn B., Hamed, Ebrahem, Selfe, Joanna, Wachtel, Marco, Walters, Zoe S., Schäfer, Beat W., Rota, Rossella, Shipley, Janet M., Hettmer, Simone
Publicado 2023

Biological Role and Clinical Implications of MYOD1(L122R) Mutation in Rhabdomyosarcoma

por Di Carlo, Daniela, Chisholm, Julia, Kelsey, Anna, Alaggio, Rita, Bisogno, Gianni, Minard-Colin, Veronique, Jenney, Meriel, Dávila Fajardo, Raquel, Merks, Johannes H. M., Shipley, Janet M., Selfe, Joanna L.
Publicado 2023

IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance

por Selfe, Joanna, Goddard, Neil C, McIntyre, Alan, Taylor, Kathryn R, Renshaw, Jane, Popov, Sergey D, Thway, Khin, Summersgill, Brenda, Huddart, Robert A, Gilbert, Duncan C, Shipley, Janet M
Publicado 2018

Genome-wide methylation analysis identifies genes silenced in non-seminoma cell lines

por Noor, Dzul Azri Mohamed, Jeyapalan, Jennie N, Alhazmi, Safiah, Carr, Matthew, Squibb, Benjamin, Wallace, Claire, Tan, Christopher, Cusack, Martin, Hughes, Jaime, Reader, Tom, Shipley, Janet, Sheer, Denise, Scotting, Paul J
Publicado 2016

Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours

por Litchfield, Kevin, Summersgill, Brenda, Yost, Shawn, Sultana, Razvan, Labreche, Karim, Dudakia, Darshna, Renwick, Anthony, Seal, Sheila, Al-Saadi, Reem, Broderick, Peter, Turner, Nicholas C., Houlston, Richard S., Huddart, Robert, Shipley, Janet, Turnbull, Clare
Publicado 2015

Identification of four new susceptibility loci for testicular germ cell tumour

por Litchfield, Kevin, Holroyd, Amy, Lloyd, Amy, Broderick, Peter, Nsengimana, Jérémie, Eeles, Rosalind, Easton, Douglas F, Dudakia, Darshna, Bishop, D. Timothy, Reid, Alison, Huddart, Robert A., Grotmol, Tom, Wiklund, Fredrik, Shipley, Janet, Houlston, Richard S., Turnbull, Clare
Publicado 2015