Pharmacokinetics, Pharmacodynamics, and Safety of the Novel Calcimimetic Agent Evocalcet in Healthy Japanese Subjects: First-in-Human Phase I Study

por Akizawa, Tadao, Shimazaki, Ryutaro, Shiramoto, Masanari, Fukagawa, Masafumi
Publicado 2018

Response to Comments on “Pharmacokinetics, Pharmacodynamics, and Safety of the Novel Calcimimetic Agent Evocalcet in Healthy Japanese Subjects: First-in-Human Phase I Study”

por Akizawa, Tadao, Shimazaki, Ryutaro, Shiramoto, Masanari, Fukagawa, Masafumi
Publicado 2019

Fast‐acting insulin aspart in Japanese patients with type 1 diabetes: Faster onset, higher early exposure and greater early glucose‐lowering effect relative to insulin aspart

por Shiramoto, Masanari, Nishida, Tomoyuki, Hansen, Ann Kathrine, Haahr, Hanne
Publicado 2017

Ultra‐Rapid Lispro results in accelerated insulin lispro absorption and faster early insulin action in comparison with Humalog(®) in Japanese patients with type 1 diabetes

por Shiramoto, Masanari, Nasu, Risa, Oura, Tomonori, Imori, Makoto, Ohwaki, Kenji
Publicado 2020

Effect of Once-Weekly Dulaglutide on Glucose Levels in Japanese Patients with Type 2 Diabetes: Findings from a Phase 4, Randomized Controlled Trial

por Inoue, Megumi, Shiramoto, Masanari, Oura, Tomonori, Nasu, Risa, Nakano, Masako, Takeuchi, Masakazu
Publicado 2019

Pharmacokinetic Bioequivalence, Safety, and Immunogenicity of DMB-3111, a Trastuzumab Biosimilar, and Trastuzumab in Healthy Japanese Adult Males: Results of a Randomized Trial

por Morita, Jun, Tanaka, Masashi, Nomoto, Masahiro, Matsuki, Shunji, Tsuru, Tomomi, Matsuguma, Kyoko, Shiramoto, Masanari
Publicado 2015

Safety and immunogenicity of a Herpes Zoster subunit vaccine in Japanese population aged ≥50 years when administered subcutaneously vs. intramuscularly

por Vink, Peter, Shiramoto, Masanari, Ogawa, Masayuki, Eda, Masahiro, Douha, Martine, Heineman, Thomas, Lal, Himal
Publicado 2016

Pharmacokinetic and pharmacodynamic similarity between SAR341402 insulin aspart and Japan-approved NovoRapid in healthy Japanese subjects

por Shiramoto, Masanari, Yoshihara, Tatsuya, Schmider, Wolfgang, Takagi, Hiroki, Nowotny, Irene, Kajiwara, Miyuki, Muto, Hideya
Publicado 2021

Similar Pharmacokinetics and Pharmacodynamics of Biosimilar SAR342434 Insulin Lispro and Japan‐Approved Humalog Insulin Lispro in Healthy Japanese Subjects

por Shiramoto, Masanari, Yoshihara, Tatsuya, Schmider, Wolfgang, Takahashi, Yoshinori, Nowotny, Irene, Kajiwara, Miyuki, Muto, Hideya
Publicado 2022

Clinical Pharmacology of Fast-Acting Insulin Aspart Versus Insulin Aspart Measured as Free or Total Insulin Aspart and the Relation to Anti-Insulin Aspart Antibody Levels in Subjec...

por Haahr, Hanne, Pieber, Thomas R., Mathieu, Chantal, Gondolf, Theis, Shiramoto, Masanari, Erichsen, Lars, Heise, Tim
Publicado 2018

Verinurad combined with febuxostat in Japanese adults with gout or asymptomatic hyperuricaemia: a phase 2a, open-label study

por Shiramoto, Masanari, Liu, Sha, Shen, Zancong, Yan, Xiaohong, Yamamoto, Amy, Gillen, Michael, Ito, Yasushi, Hall, Jesse
Publicado 2018

G protein‐coupled receptor 119 agonist DS‐8500a effects on pancreatic β‐cells in Japanese type 2 diabetes mellitus patients

por Watada, Hirotaka, Shiramoto, Masanari, Irie, Shin, Terauchi, Yasuo, Yamada, Yuichiro, Shiosakai, Kazuhito, Myobatake, Yusuke, Taguchi, Takashi
Publicado 2018

Pharmacokinetic interactions of esaxerenone with amlodipine and digoxin in healthy Japanese subjects

por Kirigaya, Yoshiaki, Shiramoto, Masanari, Ishizuka, Tomoko, Uchimaru, Hinako, Irie, Shin, Kato, Manabu, Shimizu, Takako, Nakatsu, Takafumi, Nishikawa, Yasuhiro, Ishizuka, Hitoshi
Publicado 2020

Effects of itraconazole and rifampicin on the single‐dose pharmacokinetics of the nonsteroidal mineralocorticoid receptor blocker esaxerenone in healthy Japanese subjects

por Kirigaya, Yoshiaki, Shiramoto, Masanari, Ishizuka, Tomoko, Uchimaru, Hinako, Irie, Shin, Kato, Manabu, Shimizu, Takako, Nakatsu, Takafumi, Nishikawa, Yasuhiro, Ishizuka, Hitoshi
Publicado 2020

Levocetirizine Oral Disintegrating Tablet: A Randomized Open‐Label Crossover Bioequivalence Study in Healthy Japanese Volunteers

por Ino, Hiroko, Shiramoto, Masanari, Eto, Takashi, Haranaka, Miwa, Irie, Shin, Terao, Takumi, Ogura, Hirofumi, Wakamatsu, Akira, Hoyano, Keiko, Nakano, Atsushi
Publicado 2020

Pharmacokinetics and pharmacodynamics of dapagliflozin in combination with insulin in Japanese patients with type 1 diabetes

por Watada, Hirotaka, Shiramoto, Masanari, Ueda, Shinya, Tang, Weifeng, Asano, Michiko, Thorén, Fredrik, Kim, Hyosung, Yajima, Toshitaka, Boulton, David W., Araki, Eiichi
Publicado 2018

Effects of DPP‐4 inhibitor linagliptin and GLP‐1 receptor agonist liraglutide on physiological response to hypoglycaemia in Japanese subjects with type 2 diabetes: A randomized, op...

por Yabe, Daisuke, Eto, Takashi, Shiramoto, Masanari, Irie, Shin, Murotani, Kenta, Seino, Yusuke, Kuwata, Hitoshi, Kurose, Takeshi, Seino, Susumu, Ahrén, Bo, Seino, Yutaka
Publicado 2016

Immunogenicity and safety of 13-valent pneumococcal conjugate vaccine when administered to healthy Japanese adults aged ≥50 years: An open-label trial

por Shiramoto, Masanari, Irie, Shin, Juergens, Christine, Yamaji, Masako, Tamai, Satoshi, Aizawa, Masakazu, Belanger, Todd, Gruber, William C, Scott, Daniel A, Schmoele-Thoma, Beate
Publicado 2014

Immunogenicity and safety of the 13-valent pneumococcal conjugate vaccine compared to the 23-valent pneumococcal polysaccharide vaccine in elderly Japanese adults

por Shiramoto, Masanari, Hanada, Ryuzo, Juergens, Christine, Shoji, Yasuko, Yoshida, Mizuki, Ballan, Barry, Cooper, David, Gruber, William C, Scott, Daniel A, Schmoele-Thoma, Beate
Publicado 2015

Assessment of CYP‐Mediated Drug Interactions for Evocalcet, a New Calcimimetic Agent, Based on In Vitro Investigations and a Cocktail Study in Humans

por Narushima, Kazuya, Maeda, Hiroshi, Shiramoto, Masanari, Endo, Yuichi, Ohtsuka, Satoko, Nakamura, Hiroaki, Nagata, Yoshinori, Uchimura, Tatsuo, Kannami, Ayako, Shimazaki, Ryutaro, Fukagawa, Masafumi, Akizawa, Tadao
Publicado 2018