Molecular Dynamics Simulations Reveal Proton Transfer Pathways in Cytochrome C-Dependent Nitric Oxide Reductase

por Pisliakov, Andrei V., Hino, Tomoya, Shiro, Yoshitsugu, Sugita, Yuji
Publicado 2012

Structural basis for heme detoxification by an ATP-binding cassette–type efflux pump in gram-positive pathogenic bacteria

por Nakamura, Hiro, Hisano, Tamao, Rahman, Md. Mahfuzur, Tosha, Takehiko, Shirouzu, Mikako, Shiro, Yoshitsugu
Publicado 2022

Crystal structure of bacterial haem importer complex in the inward-facing conformation

por Naoe, Youichi, Nakamura, Nozomi, Doi, Akihiro, Sawabe, Mia, Nakamura, Hiro, Shiro, Yoshitsugu, Sugimoto, Hiroshi
Publicado 2016

H(2)O(2)-dependent substrate oxidation by an engineered diiron site in a bacterial hemerythrin

por Okamoto, Yasunori, Onoda, Akira, Sugimoto, Hiroshi, Takano, Yu, Hirota, Shun, Kurtz, Donald M., Shiro, Yoshitsugu, Hayashi, Takashi
Publicado 2014

Identification of a novel zinc-binding protein, C1orf123, as an interactor with a heavy metal-associated domain

por Furukawa, Yoshiaki, Lim, Carolyn, Tosha, Takehiko, Yoshida, Koki, Hagai, Tomoaki, Akiyama, Shuji, Watanabe, Shoji, Nakagome, Kenta, Shiro, Yoshitsugu
Publicado 2018

Spatially restricted substrate-binding site of cortisol-synthesizing CYP11B1 limits multiple hydroxylations and hinders aldosterone synthesis

por Mukai, Kuniaki, Sugimoto, Hiroshi, Kamiya, Katsumasa, Suzuki, Reiko, Matsuura, Tomomi, Hishiki, Takako, Shimada, Hideo, Shiro, Yoshitsugu, Suematsu, Makoto, Kagawa, Norio
Publicado 2021

Characterization of the quinol-dependent nitric oxide reductase from the pathogen Neisseria meningitidis, an electrogenic enzyme

por Gonska, Nathalie, Young, David, Yuki, Riki, Okamoto, Takuya, Hisano, Tamao, Antonyuk, Svetlana, Hasnain, S. Samar, Muramoto, Kazumasa, Shiro, Yoshitsugu, Tosha, Takehiko, Ädelroth, Pia
Publicado 2018

Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival

por Nishinaga, Megumi, Sugimoto, Hiroshi, Nishitani, Yudai, Nagai, Seina, Nagatoishi, Satoru, Muraki, Norifumi, Tosha, Takehiko, Tsumoto, Kouhei, Aono, Shigetoshi, Shiro, Yoshitsugu, Sawai, Hitomi
Publicado 2021

Highly malleable haem-binding site of the haemoprotein HasA permits stable accommodation of bulky tetraphenylporphycenes

por Sakakibara, Erika, Shisaka, Yuma, Onoda, Hiroki, Koga, Daiki, Xu, Ning, Ono, Toshikazu, Hisaeda, Yoshio, Sugimoto, Hiroshi, Shiro, Yoshitsugu, Watanabe, Yoshihito, Shoji, Osami
Publicado 2019

Dimeric structures of quinol-dependent nitric oxide reductases (qNORs) revealed by cryo–electron microscopy

por Gopalasingam, Chai C., Johnson, Rachel M., Chiduza, George N., Tosha, Takehiko, Yamamoto, Masaki, Shiro, Yoshitsugu, Antonyuk, Svetlana V., Muench, Stephen P., Hasnain, S. Samar
Publicado 2019

The active form of quinol-dependent nitric oxide reductase from Neisseria meningitidis is a dimer

por Jamali, M. Arif M., Gopalasingam, Chai C., Johnson, Rachel M., Tosha, Takehiko, Muramoto, Kazumasa, Muench, Stephen P., Antonyuk, Svetlana V., Shiro, Yoshitsugu, Hasnain, Samar S.
Publicado 2020

A nearly on-axis spectroscopic system for simultaneously measuring UV–visible absorption and X-ray diffraction in the SPring-8 structural genomics beamline

por Sakaguchi, Miyuki, Kimura, Tetsunari, Nishida, Takuma, Tosha, Takehiko, Sugimoto, Hiroshi, Yamaguchi, Yoshihiro, Yanagisawa, Sachiko, Ueno, Go, Murakami, Hironori, Ago, Hideo, Yamamoto, Masaki, Ogura, Takashi, Shiro, Yoshitsugu, Kubo, Minoru
Publicado 2016

Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate

por Ganasen, Menega, Togashi, Hiromi, Takeda, Hanae, Asakura, Honami, Tosha, Takehiko, Yamashita, Keitaro, Hirata, Kunio, Nariai, Yuko, Urano, Takeshi, Yuan, Xiaojing, Hamza, Iqbal, Mauk, A. Grant, Shiro, Yoshitsugu, Sugimoto, Hiroshi, Sawai, Hitomi
Publicado 2018

Capacity of extracellular globins to reduce liver fibrosis via scavenging reactive oxygen species and promoting MMP-1 secretion

por Hieu, Vu Ngoc, Thuy, Le Thi Thanh, Hai, Hoang, Dat, Ninh Quoc, Hoang, Dinh Viet, Hanh, Ngo Vinh, Phuong, Dong Minh, Hoang, Truong Huu, Sawai, Hitomi, Shiro, Yoshitsugu, Sato-Matsubara, Misako, Oikawa, Daisuke, Tokunaga, Fuminori, Yoshizato, Katsutoshi, Kawada, Norifumi
Publicado 2022

XFEL Crystal Structures of Peroxidase Compound II

por Kwon, Hanna, Basran, Jaswir, Pathak, Chinar, Hussain, Mahdi, Freeman, Samuel L., Fielding, Alistair J., Bailey, Anna J., Stefanou, Natalia, Sparkes, Hazel A., Tosha, Takehiko, Yamashita, Keitaro, Hirata, Kunio, Murakami, Hironori, Ueno, Go, Ago, Hideo, Tono, Kensuke, Yamamoto, Masaki, Sawai, Hitomi, Shiro, Yoshitsugu, Sugimoto, Hiroshi, Raven, Emma L., Moody, Peter C. E.
Publicado 2021

Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate

por Tosha, Takehiko, Nomura, Takashi, Nishida, Takuma, Saeki, Naoya, Okubayashi, Kouta, Yamagiwa, Raika, Sugahara, Michihiro, Nakane, Takanori, Yamashita, Keitaro, Hirata, Kunio, Ueno, Go, Kimura, Tetsunari, Hisano, Tamao, Muramoto, Kazumasa, Sawai, Hitomi, Takeda, Hanae, Mizohata, Eiichi, Yamashita, Ayumi, Kanematsu, Yusuke, Takano, Yu, Nango, Eriko, Tanaka, Rie, Nureki, Osamu, Shoji, Osami, Ikemoto, Yuka, Murakami, Hironori, Owada, Shigeki, Tono, Kensuke, Yabashi, Makina, Yamamoto, Masaki, Ago, Hideo, Iwata, So, Sugimoto, Hiroshi, Shiro, Yoshitsugu, Kubo, Minoru
Publicado 2017

Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases

por Nishida, Yuya, Yanagisawa, Sachiko, Morita, Rikuri, Shigematsu, Hideki, Shinzawa-Itoh, Kyoko, Yuki, Hitomi, Ogasawara, Satoshi, Shimuta, Ken, Iwamoto, Takashi, Nakabayashi, Chisa, Matsumura, Waka, Kato, Hisakazu, Gopalasingam, Chai, Nagao, Takemasa, Qaqorh, Tasneem, Takahashi, Yusuke, Yamazaki, Satoru, Kamiya, Katsumasa, Harada, Ryuhei, Mizuno, Nobuhiro, Takahashi, Hideyuki, Akeda, Yukihiro, Ohnishi, Makoto, Ishii, Yoshikazu, Kumasaka, Takashi, Murata, Takeshi, Muramoto, Kazumasa, Tosha, Takehiko, Shiro, Yoshitsugu, Honma, Teruki, Shigeta, Yasuteru, Kubo, Minoru, Takashima, Seiji, Shintani, Yasunori
Publicado 2022

Author Correction: Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases

por Nishida, Yuya, Yanagisawa, Sachiko, Morita, Rikuri, Shigematsu, Hideki, Shinzawa-Itoh, Kyoko, Yuki, Hitomi, Ogasawara, Satoshi, Shimuta, Ken, Iwamoto, Takashi, Nakabayashi, Chisa, Matsumura, Waka, Kato, Hisakazu, Gopalasingam, Chai, Nagao, Takemasa, Qaqorh, Tasneem, Takahashi, Yusuke, Yamazaki, Satoru, Kamiya, Katsumasa, Harada, Ryuhei, Mizuno, Nobuhiro, Takahashi, Hideyuki, Akeda, Yukihiro, Ohnishi, Makoto, Ishii, Yoshikazu, Kumasaka, Takashi, Murata, Takeshi, Muramoto, Kazumasa, Tosha, Takehiko, Shiro, Yoshitsugu, Honma, Teruki, Shigeta, Yasuteru, Kubo, Minoru, Takashima, Seiji, Shintani, Yasunori
Publicado 2022