Probing of Exosites Leads to Novel Inhibitor Scaffolds of HCV NS3/4A Proteinase

por Shiryaev, Sergey A., Cheltsov, Anton V., Strongin, Alex Y.
Publicado 2012

Distinct Interactions with Cellular E-Cadherin of the Two Virulent Metalloproteinases Encoded by a Bacteroides fragilis Pathogenicity Island

por Remacle, Albert G., Shiryaev, Sergey A., Strongin, Alex Y.
Publicado 2014

Potential Therapeutic Targeting of Coronavirus Spike Glycoprotein Priming

por Barile, Elisa, Baggio, Carlo, Gambini, Luca, Shiryaev, Sergey A., Strongin, Alex Y., Pellecchia, Maurizio
Publicado 2020

Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis

por Remacle, Albert G, Cieplak, Piotr, Hyun, Dong Nam, Shiryaev, Sergey A, Ge, Xin, Strongin, Alex Y
Publicado 2016

A Femtomol Range FRET Biosensor Reports Exceedingly Low Levels of Cell Surface Furin: Implications for the Processing of Anthrax Protective Antigen

por Gawlik, Katarzyna, Remacle, Albert G., Shiryaev, Sergey A., Golubkov, Vladislav S., Ouyang, Mingxing, Wang, Yingxiao, Strongin, Alex Y.
Publicado 2010

Matrix Metalloproteinase Proteolysis of the Myelin Basic Protein Isoforms Is a Source of Immunogenic Peptides in Autoimmune Multiple Sclerosis

por Shiryaev, Sergey A., Savinov, Alexei Y., Cieplak, Piotr, Ratnikov, Boris I., Motamedchaboki, Khatereh, Smith, Jeffrey W., Strongin, Alex Y.
Publicado 2009

Allosteric Inhibitors of Zika Virus NS2B-NS3 Protease Targeting Protease in “Super-Open” Conformation

por Meewan, Ittipat, Shiryaev, Sergey A., Kattoula, Julius, Huang, Chun-Teng, Lin, Vivian, Chuang, Chiao-Han, Terskikh, Alexey V., Abagyan, Ruben
Publicado 2023

Autocatalytic Activation of the Furin Zymogen Requires Removal of the Emerging Enzyme's N-Terminus from the Active Site

por Gawlik, Katarzyna, Shiryaev, Sergey A., Zhu, Wenhong, Motamedchaboki, Khatereh, Desjardins, Roxane, Day, Robert, Remacle, Albert G., Stec, Boguslaw, Strongin, Alex Y.
Publicado 2009

New Details of HCV NS3/4A Proteinase Functionality Revealed by a High-Throughput Cleavage Assay

por Shiryaev, Sergey A., Thomsen, Elliot R., Cieplak, Piotr, Chudin, Eugene, Cheltsov, Anton V., Chee, Mark S., Kozlov, Igor A., Strongin, Alex Y.
Publicado 2012

Partial Jacobsen syndrome phenotype in a patient with a de novo frameshift mutation in the ETS1 transcription factor

por Tootleman, Eva, Malamut, Barbara, Akshoomoff, Natacha, Mattson, Sarah N., Hoffman, Hal M., Jones, Marilyn C., Printz, Beth, Shiryaev, Sergey A., Grossfeld, Paul
Publicado 2019

High-Resolution Analysis and Functional Mapping of Cleavage Sites and Substrate Proteins of Furin in the Human Proteome

por Shiryaev, Sergey A., Chernov, Andrei V., Golubkov, Vladislav S., Thomsen, Elliot R., Chudin, Eugene, Chee, Mark S., Kozlov, Igor A., Strongin, Alex Y., Cieplak, Piotr
Publicado 2013

Immunodominant fragments of myelin basic protein initiate T cell-dependent pain

por Liu, Huaqing, Shiryaev, Sergey A, Chernov, Andrei V, Kim, Youngsoon, Shubayev, Igor, Remacle, Albert G, Baranovskaya, Svetlana, Golubkov, Vladislav S, Strongin, Alex Y, Shubayev, Veronica I
Publicado 2012

The alternatively spliced fibronectin CS1 isoform regulates IL-17A levels and mechanical allodynia after peripheral nerve injury

por Liu, Huaqing, Dolkas, Jennifer, Hoang, Khan, Angert, Mila, Chernov, Andrei V., Remacle, Albert G., Shiryaev, Sergey A., Strongin, Alex Y., Nishihara, Tasuku, Shubayev, Veronica I.
Publicado 2015

Zika Virus: Origins, Pathological Action, and Treatment Strategies

por Gorshkov, Kirill, Shiryaev, Sergey A., Fertel, Sophie, Lin, Yi-Wen, Huang, Chun-Teng, Pinto, Antonella, Farhy, Chen, Strongin, Alex Y., Zheng, Wei, Terskikh, Alexey V.
Publicado 2019

Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis

por Shiryaev, Sergey A., Mesci, Pinar, Pinto, Antonella, Fernandes, Isabella, Sheets, Nicholas, Shresta, Sujan, Farhy, Chen, Huang, Chun-Teng, Strongin, Alex Y., Muotri, Alysson R., Terskikh, Alexey V.
Publicado 2017

The MMP-9/TIMP-1 Axis Controls the Status of Differentiation and Function of Myelin-Forming Schwann Cells in Nerve Regeneration

por Kim, Youngsoon, Remacle, Albert G., Chernov, Andrei V., Liu, Huaqing, Shubayev, Igor, Lai, Calvin, Dolkas, Jennifer, Shiryaev, Sergey A., Golubkov, Vladislav S., Mizisin, Andrew P., Strongin, Alex Y., Shubayev, Veronica I.
Publicado 2012

Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with an endemic human CoV

por Ladner, Jason T, Henson, Sierra N, Boyle, Annalee S, Engelbrektson, Anna L, Fink, Zane W, Rahee, Fatima, D’ambrozio, Jonathan, Schaecher, Kurt E, Stone, Mars, Dong, Wenjuan, Dadwal, Sanjeet, Yu, Jianhua, Caligiuri, Michael A, Cieplak, Piotr, Bjørås, Magnar, Fenstad, Mona H, Nordbø, Svein A, Kainov, Denis E, Muranaka, Norihito, Chee, Mark S, Shiryaev, Sergey A, Altin, John A
Publicado 2020

Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses

por Ladner, Jason T., Henson, Sierra N., Boyle, Annalee S., Engelbrektson, Anna L., Fink, Zane W., Rahee, Fatima, D’ambrozio, Jonathan, Schaecher, Kurt E., Stone, Mars, Dong, Wenjuan, Dadwal, Sanjeet, Yu, Jianhua, Caligiuri, Michael A., Cieplak, Piotr, Bjørås, Magnar, Fenstad, Mona H., Nordbø, Svein A., Kainov, Denis E., Muranaka, Norihito, Chee, Mark S., Shiryaev, Sergey A., Altin, John A.
Publicado 2021

Blocking Zika virus vertical transmission

por Mesci, Pinar, Macia, Angela, Moore, Spencer M., Shiryaev, Sergey A., Pinto, Antonella, Huang, Chun-Teng, Tejwani, Leon, Fernandes, Isabella R., Suarez, Nicole A., Kolar, Matthew J., Montefusco, Sandro, Rosenberg, Scott C., Herai, Roberto H., Cugola, Fernanda R., Russo, Fabiele B., Sheets, Nicholas, Saghatelian, Alan, Shresta, Sujan, Momper, Jeremiah D., Siqueira-Neto, Jair L., Corbett, Kevin D., Beltrão-Braga, Patricia C. B., Terskikh, Alexey V., Muotri, Alysson R.
Publicado 2018

Author Correction: Blocking Zika virus vertical transmission

por Mesci, Pinar, Macia, Angela, Moore, Spencer M., Shiryaev, Sergey A., Pinto, Antonella, Huang, Chun-Teng, Tejwani, Leon, Fernandes, Isabella R., Suarez, Nicole A., Kolar, Matthew J., Montefusco, Sandro, Rosenberg, Scott C., Herai, Roberto H., Cugola, Fernanda R., Russo, Fabiele B., Sheets, Nicholas, Saghatelian, Alan, Shresta, Sujan, Momper, Jeremiah D., Siqueira-Neto, Jair L., Corbett, Kevin D., Beltrão-Braga, Patricia C. B., Terskikh, Alexey V., Muotri, Alysson R.
Publicado 2018