Intraring allostery controls the function and assembly of a hetero-oligomeric class II chaperonin

por Shoemark, Deborah K., Sessions, Richard B., Brancaccio, Andrea, Bigotti, Maria Giulia
Publicado 2018

Ca(2+) Regulates Dimerization of the BAR Domain Protein PICK1 and Consequent Membrane Curvature

por Stan, Georgiana F., Shoemark, Deborah K., Alibhai, Dominic, Hanley, Jonathan G.
Publicado 2022

Identification and validation of novel microtubule suppressors with an imidazopyridine scaffold through structure-based virtual screening and docking

por Elseginy, Samia A., Oliveira, A. Sofia F., Shoemark, Deborah K., Sessions, Richard B.
Publicado 2022

SARS-CoV-2 spike variants differ in their allosteric responses to linoleic acid

por Oliveira, A Sofia F, Shoemark, Deborah K, Davidson, Andrew D, Berger, Imre, Schaffitzel, Christiane, Mulholland, Adrian J
Publicado 2023

Emergence of a Thrombospondin Superfamily at the Origin of Metazoans

por Shoemark, Deborah K, Ziegler, Berenice, Watanabe, Hiroshi, Strompen, Jennifer, Tucker, Richard P, Özbek, Suat, Adams, Josephine C
Publicado 2019

The fatty acid site is coupled to functional motifs in the SARS-CoV-2 spike protein and modulates spike allosteric behaviour

por Sofia F. Oliveira, A., Shoemark, Deborah K., Avila Ibarra, Amaurys, Davidson, Andrew D., Berger, Imre, Schaffitzel, Christiane, Mulholland, Adrian J.
Publicado 2021

Identification of β-strand mediated protein–protein interaction inhibitors using ligand-directed fragment ligation

por Hegedüs, Zsófia, Hóbor, Fruzsina, Shoemark, Deborah K., Celis, Sergio, Lian, Lu-Yun, Trinh, Chi H., Sessions, Richard B., Edwards, Thomas A., Wilson, Andrew J.
Publicado 2021

ATG8-dependent LMX1B-autophagy crosstalk shapes human midbrain dopaminergic neuronal resilience

por Jiménez-Moreno, Natalia, Kollareddy, Madhu, Stathakos, Petros, Moss, Joanna J., Antón, Zuriñe, Shoemark, Deborah K., Sessions, Richard B., Witzgall, Ralph, Caldwell, Maeve, Lane, Jon D.
Publicado 2023

16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer’s Post-Mortem Brain

por Emery, David C., Shoemark, Deborah K., Batstone, Tom E., Waterfall, Christy M., Coghill, Jane A., Cerajewska, Tanya L., Davies, Maria, West, Nicola X., Allen, Shelley J.
Publicado 2017

Simulations support the interaction of the SARS-CoV-2 spike protein with nicotinic acetylcholine receptors

por Oliveira, A. Sofia F., Ibarra, Amaurys Avila, Bermudez, Isabel, Casalino, Lorenzo, Gaieb, Zied, Shoemark, Deborah K., Gallagher, Timothy, Sessions, Richard B., Amaro, Rommie E., Mulholland, Adrian J.
Publicado 2020

A potential interaction between the SARS-CoV-2 spike protein and nicotinic acetylcholine receptors

por Oliveira, A. Sofia F., Ibarra, Amaurys Avila, Bermudez, Isabel, Casalino, Lorenzo, Gaieb, Zied, Shoemark, Deborah K., Gallagher, Timothy, Sessions, Richard B., Amaro, Rommie E., Mulholland, Adrian J.
Publicado 2021

Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein

por Davidson, Andrew D., Williamson, Maia Kavanagh, Lewis, Sebastian, Shoemark, Deborah, Carroll, Miles W., Heesom, Kate J., Zambon, Maria, Ellis, Joanna, Lewis, Philip A., Hiscox, Julian A., Matthews, David A.
Publicado 2020

Antiproliferative and Antimigratory Effects of a Novel YAP–TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking

por Smith, Sarah A., Sessions, Richard B., Shoemark, Deborah K., Williams, Christopher, Ebrahimighaei, Reza, McNeill, Madeleine C., Crump, Matthew P., McKay, Tristan R., Harris, Gemma, Newby, Andrew C., Bond, Mark
Publicado 2019

The de novo design of a biocompatible and functional integral membrane protein using minimal sequence complexity

por Lalaurie, Christophe J., Dufour, Virginie, Meletiou, Anna, Ratcliffe, Sarah, Harland, Abigail, Wilson, Olivia, Vamasiri, Chiratchaya, Shoemark, Deborah K., Williams, Christopher, Arthur, Christopher J., Sessions, Richard B., Crump, Matthew P., Anderson, J. L. Ross, Curnow, Paul
Publicado 2018

Small-residue packing motifs modulate the structure and function of a minimal de novo membrane protein

por Curnow, Paul, Hardy, Benjamin J., Dufour, Virginie, Arthur, Christopher J., Stenner, Richard, Hodgson, Lorna R., Verkade, Paul, Williams, Christopher, Shoemark, Deborah K., Sessions, Richard B., Crump, Matthew P., Jones, Michael R., Anderson, J. L. Ross
Publicado 2020

Query-guided protein–protein interaction inhibitor discovery

por Celis, Sergio, Hobor, Fruzsina, James, Thomas, Bartlett, Gail J., Ibarra, Amaurys A., Shoemark, Deborah K., Hegedüs, Zsófia, Hetherington, Kristina, Woolfson, Derek N., Sessions, Richard B., Edwards, Thomas A., Andrews, David M., Nelson, Adam, Wilson, Andrew J.
Publicado 2021

Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein

por Toelzer, Christine, Gupta, Kapil, Yadav, Sathish K. N., Borucu, Ufuk, Davidson, Andrew D., Kavanagh Williamson, Maia, Shoemark, Deborah K., Garzoni, Frederic, Staufer, Oskar, Milligan, Rachel, Capin, Julien, Mulholland, Adrian J., Spatz, Joachim, Fitzgerald, Daniel, Berger, Imre, Schaffitzel, Christiane
Publicado 2020

Characterization and evolutionary origin of novel C2H2 zinc finger protein (ZNF648) required for both erythroid and megakaryocyte differentiation in humans

por Ferguson, Daniel C. J., Mokim, Juraidah Haji, Meinders, Marjolein, Moody, Edmund R. R., Williams, Tom A., Cooke, Sarah, Trakarnsanga, Kongtana, Daniels, Deborah E., Ferrer-Vicens, Ivan, Shoemark, Deborah, Tipgomut, Chartsiam, Macinnes, Katherine A., Wilson, Marieangela C., Singleton, Belinda K., Frayne, Jan
Publicado 2020

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

por Simonetti, Boris, Daly, James L., Simón-Gracia, Lorena, Klein, Katja, Weeratunga, Saroja, Antón-Plágaro, Carlos, Tobi, Allan, Hodgson, Lorna, Lewis, Philip A., Heesom, Kate J., Shoemark, Deborah K., Davidson, Andrew D., Collins, Brett M., Teesalu, Tambet, Yamauchi, Yohei, Cullen, Peter J.
Publicado 2022

Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2

por Gupta, Kapil, Toelzer, Christine, Williamson, Maia Kavanagh, Shoemark, Deborah K., Oliveira, A. Sofia F., Matthews, David A., Almuqrin, Abdulaziz, Staufer, Oskar, Yadav, Sathish K. N., Borucu, Ufuk, Garzoni, Frederic, Fitzgerald, Daniel, Spatz, Joachim, Mulholland, Adrian J., Davidson, Andrew D., Schaffitzel, Christiane, Berger, Imre
Publicado 2022