Therapy for Mycobacterium kansasii Infection: Beyond 2018

por DeStefano, Michelle S., Shoen, Carolyn M., Cynamon, Michael H.
Publicado 2018

2148. In vitro Potency of a Leucyl-tRNA Synthetase Inhibitor, MRX-6038, Against Mycobacterium tuberculosis, Mycobacterium avium, and Mycobacterium abscessus

por Shoen, Carolyn M, DeStefano, Michelle S, Wang, Wen, Cynamon, Michael H
Publicado 2023

Developing Tadpole Xenopus laevis as a Comparative Animal Model to Study Mycobacterium abscessus Pathogenicity

por Lopez, Arianna, Shoen, Carolyn, Cynamon, Michael, Dimitrakopoulou, Dionysia, Paiola, Matthieu, Pavelka, Martin S., Robert, Jacques
Publicado 2021

1704. Epetraborole, a Novel Bacterial Leucyl-tRNA Synthetase Inhibitor, Demonstrates Potent Efficacy and Improves Efficacy of Standard of Care Regimen Against Mycobacterium avium c...

por De, Kavita, DeStefano, Michelle S, Shoen, Carolyn, Cynamon, Michael H, Alley, M R K
Publicado 2022

Repurposing Avermectins and Milbemycins against Mycobacteroides abscessus and Other Nontuberculous Mycobacteria

por Muñoz-Muñoz, Lara, Shoen, Carolyn, Sweet, Gaye, Vitoria, Asunción, Bull, Tim J., Cynamon, Michael, Thompson, Charles J., Ramón-García, Santiago
Publicado 2021

Culture-Free Enumeration of Mycobacterium tuberculosis in Mouse Tissues Using the Molecular Bacterial Load Assay for Preclinical Drug Development

por Evangelopoulos, Dimitrios, Shoen, Carolyn M., Honeyborne, Isobella, Clark, Simon, Williams, Ann, Mukamolova, Galina V., Cynamon, Michael H., McHugh, Timothy D.
Publicado 2022

Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis

por Hajian, Behnoush, Scocchera, Eric, Keshipeddy, Santosh, G-Dayanandan, Narendran, Shoen, Carolyn, Krucinska, Jolanta, Reeve, Stephanie, Cynamon, Michael, Anderson, Amy C., Wright, Dennis L.
Publicado 2016

New Classes of Alanine Racemase Inhibitors Identified by High-Throughput Screening Show Antimicrobial Activity against Mycobacterium tuberculosis

por Anthony, Karen G., Strych, Ulrich, Yeung, Kacheong R., Shoen, Carolyn S., Perez, Oriana, Krause, Kurt L., Cynamon, Michael H., Aristoff, Paul A., Koski, Raymond A.
Publicado 2011

A Modified Bacillus Calmette-Guérin (BCG) Vaccine with Reduced Activity of Antioxidants and Glutamine Synthetase Exhibits Enhanced Protection of Mice despite Diminished in Vivo Per...

por Shoen, Carolyn M., DeStefano, Michelle S., Hager, Cynthia C., Tham, Kyi-Toe, Braunstein, Miriam, Allen, Alexandria D., Gates, Hiriam O., Cynamon, Michael H., Kernodle, Douglas S.
Publicado 2013

Metabolic and Bactericidal Effects of Targeted Suppression of NadD and NadE Enzymes in Mycobacteria

por Rodionova, Irina A., Schuster, Brian M., Guinn, Kristine M., Sorci, Leonardo, Scott, David A., Li, Xiaoqing, Kheterpal, Indu, Shoen, Carolyn, Cynamon, Michael, Locher, Christopher, Rubin, Eric J., Osterman, Andrei L.
Publicado 2014

A polymeric approach toward resistance-resistant antimicrobial agent with dual-selective mechanisms of action

por Bai, Silei, Wang, Jianxue, Yang, Kailing, Zhou, Cailing, Xu, Yangfan, Song, Junfeng, Gu, Yuanxin, Chen, Zheng, Wang, Min, Shoen, Carolyn, Andrade, Brenda, Cynamon, Michael, Zhou, Kai, Wang, Hui, Cai, Qingyun, Oldfield, Eric, Zimmerman, Steven C., Bai, Yugang, Feng, Xinxin
Publicado 2021

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

por Pethe, Kevin, Sequeira, Patricia C., Agarwalla, Sanjay, Rhee, Kyu, Kuhen, Kelli, Phong, Wai Yee, Patel, Viral, Beer, David, Walker, John R., Duraiswamy, Jeyaraj, Jiricek, Jan, Keller, Thomas H., Chatterjee, Arnab, Tan, Mai Ping, Ujjini, Manjunatha, Rao, Srinivasa P.S., Camacho, Luis, Bifani, Pablo, Mak, Puiying A., Ma, Ida, Barnes, S. Whitney, Chen, Zhong, Plouffe, David, Thayalan, Pamela, Ng, Seow Hwee, Au, Melvin, Lee, Boon Heng, Tan, Bee Huat, Ravindran, Sindhu, Nanjundappa, Mahesh, Lin, Xiuhua, Goh, Anne, Lakshminarayana, Suresh B., Shoen, Carolyn, Cynamon, Michael, Kreiswirth, Barry, Dartois, Veronique, Peters, Eric C., Glynne, Richard, Brenner, Sydney, Dick, Thomas
Publicado 2010