High Expression of RECQL Protein in ER-Positive Breast Tumours Is Associated With a Better Survival

por Mahmoodi, Ardalan, Shoqafi, Ahmed, Sun, Ping, Giannakeas, Vasily, Cybulski, Cezary, Nofech-Mozes, Sharon, Masson, Jean-Yves, Sharma, Sudha, Samani, Amir Abbas, Madhusudan, Srinivasan, Narod, Steven A., Akbari, Mohammad R.
Publicado 2022

Unravelling the clinicopathological and functional significance of replication protein A (RPA) heterotrimeric complex in breast cancers

por Algethami, Mashael, Toss, Michael S., Woodcock, Corinne L., Jaipal, Chandar, Brownlie, Juliette, Shoqafi, Ahmed, Alblihy, Adel, Mesquita, Katia A., Green, Andrew R., Mongan, Nigel P., Jeyapalan, Jennie N., Rakha, Emad A., Madhusudan, Srinivasan
Publicado 2023

Untangling the clinicopathological significance of MRE11-RAD50-NBS1 complex in sporadic breast cancers

por Alblihy, Adel, Shoqafi, Ahmed, Toss, Michael S., Algethami, Mashael, Harris, Anna E., Jeyapalan, Jennie N., Abdel-Fatah, Tarek, Servante, Juliette, Chan, Stephen Y. T., Green, Andrew, Mongan, Nigel P., Rakha, Emad A., Madhusudan, Srinivasan
Publicado 2021

Targeting Mre11 overcomes platinum resistance and induces synthetic lethality in XRCC1 deficient epithelial ovarian cancers

por Alblihy, Adel, Ali, Reem, Algethami, Mashael, Shoqafi, Ahmed, Toss, Michael S., Brownlie, Juliette, Tatum, Natalie J., Hickson, Ian, Moran, Paloma Ordonez, Grabowska, Anna, Jeyapalan, Jennie N., Mongan, Nigel P., Rakha, Emad A., Madhusudan, Srinivasan
Publicado 2022

Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers

por Ali, Reem, Alabdullah, Muslim, Algethami, Mashael, Alblihy, Adel, Miligy, Islam, Shoqafi, Ahmed, Mesquita, Katia A., Abdel-Fatah, Tarek, Chan, Stephen YT, Chiang, Pei Wen, Mongan, Nigel P, Rakha, Emad A, Tomkinson, Alan E, Madhusudan, Srinivasan
Publicado 2021

Selective Killing of BRCA2-Deficient Ovarian Cancer Cells via MRE11 Blockade

por Alblihy, Adel, Ali, Reem, Algethami, Mashael, Ritchie, Alison A., Shoqafi, Ahmed, Alqahtani, Shatha, Mesquita, Katia A., Toss, Michael S., Ordóñez-Morán, Paloma, Jeyapalan, Jennie N., Dekker, Lodewijk, Salerno, Martina, Hartsuiker, Edgar, Grabowska, Anna M., Rakha, Emad A., Mongan, Nigel P., Madhusudan, Srinivasan
Publicado 2023