New strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncology

por Roulston, Anne, Shore, Gordon C.
Publicado 2015

Direct Membrane Insertion of Voltage-dependent Anion-selective Channel Protein Catalyzed by Mitochondrial Tom20

por Schleiff, Enrico, Silvius, John R., Shore, Gordon C.
Publicado 1999

Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

por Breckenridge, David G., Stojanovic, Marina, Marcellus, Richard C., Shore, Gordon C.
Publicado 2003

Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy

por Cole, Jonathan, Guiot, Marie-Christine, Gravel, Michel, Bernier, Cynthia, Shore, Gordon C., Roulston, Anne
Publicado 2017

Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim

por Nguyen, Mai, Cencic, Regina, Ertel, Franziska, Bernier, Cynthia, Pelletier, Jerry, Roulston, Anne, Silvius, John R., Shore, Gordon C.
Publicado 2015

Regulated Targeting of BAX to Mitochondria

por Goping, Ing Swie, Gross, Atan, Lavoie, Josée N., Nguyen, Mai, Jemmerson, Ronald, Roth, Kevin, Korsmeyer, Stanley J., Shore, Gordon C.
Publicado 1998

p28 Bap31, a Bcl-2/Bcl-X(L)- and Procaspase-8–associated Protein in the Endoplasmic Reticulum

por Ng, Florence W.H., Nguyen, Mai, Kwan, Tony, Branton, Philip E., Nicholson, Donald W., Cromlish, James A., Shore, Gordon C.
Publicado 1997

Granzyme B–Mediated Cytochrome C Release Is Regulated by the Bcl-2 Family Members Bid and Bax

por Heibein, Jeffrey A., Goping, Ing Swie, Barry, Michele, Pinkoski, Michael J., Shore, Gordon C., Green, Douglas R., Bleackley, R. Chris
Publicado 2000

DZ-2384 has a superior preclinical profile to taxanes for the treatment of triple-negative breast cancer and is synergistic with anti-CTLA-4 immunotherapy

por Bernier, Cynthia, Soliman, Ahmed, Gravel, Michel, Dankner, Matthew, Savage, Paul, Petrecca, Kevin, Park, Morag, Siegel, Peter M., Shore, Gordon C., Roulston, Anne
Publicado 2018

Improvement of Pharmacokinetic Profile of TRAIL via Trimer-Tag Enhances its Antitumor Activity in vivo

por Liu, Haipeng, Su, Danmei, Zhang, Jinlong, Ge, Shuaishuai, Li, Youwei, Wang, Fei, Gravel, Michel, Roulston, Anne, Song, Qin, Xu, Wei, Liang, Joshua G., Shore, Gordon, Wang, Xiaodong, Liang, Peng
Publicado 2017

Author Correction: Improvement of Pharmacokinetic Profile of TRAIL via Trimer-Tag Enhances its Antitumor Activity in vivo

por Liu, Haipeng, Su, Danmei, Zhang, Jinlong, Ge, Shuaishuai, Li, Youwei, Wang, Fei, Gravel, Michel, Roulston, Anne, Song, Qin, Xu, Wei, Liang, Joshua G., Shore, Gordon, Wang, Xiaodong, Liang, Peng
Publicado 2018

Bcl-x(L) regulates metabolic efficiency of neurons through interaction with the mitochondrial F(1)F(O) ATP synthase

por Alavian, Kambiz N., Li, Hongmei, Collis, Leon, Bonanni, Laura, Zeng, Lu, Sacchetti, Silvio, Lazrove, Emma, Nabili, Panah, Flaherty, Benjamin, Graham, Morven, Chen, Yingbei, Messerli, Shanta, Mariggio, Maria A., Rahner, Christoph, McNay, Ewan, Shore, Gordon, Smith, Peter J. S., Hardwick, J. Marie, Jonas, Elizabeth A.
Publicado 2011