The SMAC mimetic, LCL-161, reduces survival in aggressive MYC-driven lymphoma while promoting susceptibility to endotoxic shock

por West, A C, Martin, B P, Andrews, D A, Hogg, S J, Banerjee, A, Grigoriadis, G, Johnstone, R W, Shortt, J
Publicado 2016

P1609: VERY LOW MORTALITY IN DOUBLE VACCINATED IMMUNOCOMPROMISED HAEMATOLOGY PATIENTS INFECTED WITH SARS-COV-2.

por Shaw, B., Shortt, J., Rogers, B., Kaplan, Z., Low, M., Gregory, G., Vilcassim, S., Grigoriadis, G., Fedele, P., Gilbertson, M., Opat, S.
Publicado 2022

P1261: ALLG LABORATORY SCIENCE STUDY LS21: MOLECULAR CORRELATES OF RESPONSE IN RELAPSED/REFRACTORY MARGINAL ZONE LYMPHOMA (RRMZL) PATIENTS TREATED WITH ZANUBRUTINIB IN THE MAGNOLIA...

por Tatarczuch, M., Waltham, M., Shortt, J., Hawkes, E., Ho, S.-J., Trotman, J., Brasacchio, D., Co, M., Li, J., Ramakrishnan, V., Dunne, K., Opat, S., Gregory, G.
Publicado 2022

CDK9 inhibition by dinaciclib potently suppresses Mcl-1 to induce durable apoptotic responses in aggressive MYC-driven B-cell lymphoma in vivo

por Gregory, G P, Hogg, S J, Kats, L M, Vidacs, E, Baker, A J, Gilan, O, Lefebure, M, Martin, B P, Dawson, M A, Johnstone, R W, Shortt, J
Publicado 2015

Preclinical screening of histone deacetylase inhibitors combined with ABT-737, rhTRAIL/MD5-1 or 5-azacytidine using syngeneic Vk*MYC multiple myeloma

por Matthews, G M, Lefebure, M, Doyle, M A, Shortt, J, Ellul, J, Chesi, M, Banks, K-M, Vidacs, E, Faulkner, D, Atadja, P, Bergsagel, P L, Johnstone, R W
Publicado 2013

P1033: A PHASE 2 STUDY OF THE LSD1 INHIBITOR IMG-7289 (BOMEDEMSTAT) FOR THE TREATMENT OF ESSENTIAL THROMBOCYTHEMIA (ET)

por Palandri, F., Ross, D. M., Cochrane, T., Tate, C., Lane, S. W., Larsen, S. R., Gerds, A. T., Halpern, A. B., Shortt, J., Rossetti, J. M., Pettit, K. M., Liang, J., Mead, A., Marchetti, M., Vannucchi, A., Wilson, A., Göthert, J. R., Hanna, M., Jones, A., Peppe, J., Natsoulis, G., McClure, T., Hong, W.-J., Stevenson, W. S., Harrison, C. N., Talpaz, M., Vianelli, N., Rienhoff, H. Y.
Publicado 2022

P1051: A PHASE 2 STUDY OF IMG-7289 (BOMEDEMSTAT) IN PATIENTS WITH ADVANCED MYELOFIBROSIS

por Gill, H., Yacoub, A., Pettit, K., Bradley, T., Gerds, A., Tatarczuch, M., Shortt, J., Curtin, N., Rossetti, J., Burbury, K., Mead, A., Göthert, J., Koschmieder, S., Jones, A., Peppe, J., Dias, J., Natsoulis, G., McClure, T., Kleppe, M., Hong, W.-J., Stevenson, W., Ewing, J., Chacko, J., Rumi, E., Halpern, A., Palandri, F., Vianelli, N., Passamonti, F., Mesa, R., Marchetti, M., Harrison, C., Vannucchi, A., Watts, J., Ross, D., Talpaz, M., Rienhoff, H.
Publicado 2022