Allosteric Regulation of G-Protein-Coupled Receptors: From Diversity of Molecular Mechanisms to Multiple Allosteric Sites and Their Ligands

por Shpakov, Alexander O.
Publicado 2023

Signal Protein-Derived Peptides as Functional Probes and Regulators of Intracellular Signaling

por Shpakov, Alexander O.
Publicado 2011

Improvement Effect of Metformin on Female and Male Reproduction in Endocrine Pathologies and Its Mechanisms

por Shpakov, Alexander O.
Publicado 2021

The Functional State of Hormone-Sensitive Adenylyl Cyclase Signaling System in Diabetes Mellitus

por Shpakov, Alexander O., Derkach, Kira V.
Publicado 2013

Brain signaling systems in the Type 2 diabetes and metabolic syndrome: promising target to treat and prevent these diseases

por Shpakov, Alexander O, Derkach, Kira V, Berstein, Lev M
Publicado 2015

Hot Spots for the Use of Intranasal Insulin: Cerebral Ischemia, Brain Injury, Diabetes Mellitus, Endocrine Disorders and Postoperative Delirium

por Shpakov, Alexander O., Zorina, Inna I., Derkach, Kira V.
Publicado 2023

The Effect of Long-Term Intranasal Serotonin Treatment on Metabolic Parameters and Hormonal Signaling in Rats with High-Fat Diet/Low-Dose Streptozotocin-Induced Type 2 Diabetes

por Derkach, Kira V., Bondareva, Vera M., Chistyakova, Oxana V., Berstein, Lev M., Shpakov, Alexander O.
Publicado 2015

Insulin and α-Tocopherol Enhance the Protective Effect of Each Other on Brain Cortical Neurons under Oxidative Stress Conditions and in Rat Two-Vessel Forebrain Ischemia/Reperfusio...

por Zakharova, Irina O., Bayunova, Liubov V., Zorina, Inna I., Sokolova, Tatiana V., Shpakov, Alexander O., Avrova, Natalia F.
Publicado 2021

The Protective Effect of Insulin on Rat Cortical Neurons in Oxidative Stress and Its Dependence on the Modulation of Akt, GSK-3beta, ERK1/2, and AMPK Activities

por Zakharova, Irina O., Sokolova, Tatiana V., Bayunova, Liubov V., Zorina, Inna I., Rychkova, Maria P., Shpakov, Alexander O., Avrova, Natalia F.
Publicado 2019

Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult,...

por Bakhtyukov, Andrey A., Derkach, Kira V., Gureev, Maxim A., Dar’in, Dmitry V., Sorokoumov, Viktor N., Romanova, Irina V., Morina, Irina Yu., Stepochkina, Anna M., Shpakov, Alexander O.
Publicado 2020

The Effects of Separate and Combined Treatment of Male Rats with Type 2 Diabetes with Metformin and Orthosteric and Allosteric Agonists of Luteinizing Hormone Receptor on Steroidog...

por Bakhtyukov, Andrey A., Derkach, Kira V., Sorokoumov, Viktor N., Stepochkina, Anna M., Romanova, Irina V., Morina, Irina Yu., Zakharova, Irina O., Bayunova, Liubov V., Shpakov, Alexander O.
Publicado 2021

Dual PTP1B/TC-PTP Inhibitors: Biological Evaluation of 3-(Hydroxymethyl)cinnoline-4(1H)-Ones

por Derkach, Kira V., Gureev, Maxim A., Babushkina, Anastasia A., Mikhaylov, Vladimir N., Zakharova, Irina O., Bakhtyukov, Andrey A., Sorokoumov, Viktor N., Novikov, Alexander S., Krasavin, Mikhail, Shpakov, Alexander O., Balova, Irina A.
Publicado 2023