2-(4-Methylsulfonylphenyl)pyrimidines as Prospective Radioligands for Imaging Cyclooxygenase-2 with PET—Synthesis, Triage, and Radiolabeling

por Cortes-Salva, Michelle Y., Shrestha, Stal, Singh, Prachi, Morse, Cheryl L., Jenko, Kimberly J., Montero Santamaria, Jose A., Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Publicado 2018

PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study

por Shrestha, Stal, Kim, Min-Jeong, Eldridge, Mark, Lehmann, Michael L., Frankland, Michael, Liow, Jeih-San, Yu, Zu-Xi, Cortes-Salva, Michelle, Telu, Sanjay, Henter, Ioline D., Gallagher, Evan, Lee, Jae-Hoon, Fredericks, J. Megan, Poffenberger, Chelsie, Tye, George, Ruiz-Perdomo, Yanira, Anaya, Fernanda Juarez, Montero Santamaria, Jose A., Gladding, Robert L., Zoghbi, Sami S., Fujita, Masahiro, Katz, James D., Pike, Victor W., Innis, Robert B.
Publicado 2020