Salmonella Effector SteA Suppresses Proinflammatory Responses of the Host by Interfering With IκB Degradation

por Gulati, Aakanksha, Shukla, Rhythm, Mukhopadhaya, Arunika
Publicado 2019

Brevibacillin 2V, a Novel Antimicrobial Lipopeptide With an Exceptionally Low Hemolytic Activity

por Zhao, Xinghong, Wang, Xiaoqi, Shukla, Rhythm, Kumar, Raj, Weingarth, Markus, Breukink, Eefjan, Kuipers, Oscar P.
Publicado 2021

Brevibacillin 2V Exerts Its Bactericidal Activity via Binding to Lipid II and Permeabilizing Cellular Membranes

por Zhao, Xinghong, Wang, Xiaoqi, Shukla, Rhythm, Kumar, Raj, Weingarth, Markus, Breukink, Eefjan, Kuipers, Oscar P.
Publicado 2021

Mode of action of teixobactins in cellular membranes

por Shukla, Rhythm, Medeiros-Silva, João, Parmar, Anish, Vermeulen, Bram J. A., Das, Sanjit, Paioni, Alessandra Lucini, Jekhmane, Shehrazade, Lorent, Joseph, Bonvin, Alexandre M. J. J., Baldus, Marc, Lelli, Moreno, Veldhuizen, Edwin J. A., Breukink, Eefjan, Singh, Ishwar, Weingarth, Markus
Publicado 2020

A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance

por van der Krift, Felix, Zijlmans, Dick W, Shukla, Rhythm, Javed, Ali, Koukos, Panagiotis I, Schwarz, Laura LE, Timmermans-Sprang, Elpetra PM, Maas, Peter EM, Gahtory, Digvijay, van den Nieuwboer, Maurits, Mol, Jan A, Strous, Ger J, Bonvin, Alexandre MJJ, van der Stelt, Mario, Veldhuizen, Edwin JA, Weingarth, Markus, Vermeulen, Michiel, Klumperman, Judith, Maurice, Madelon M
Publicado 2023

A new antibiotic from an uncultured bacterium binds to an immutable target

por Shukla, Rhythm, Peoples, Aaron J., Ludwig, Kevin C., Maity, Sourav, Derks, Maik G.N., de Benedetti, Stefania, Krueger, Annika M, Vermeulen, Bram J.A., Lavore, Francesca, Honorato, Rodrigo V., Grein, Fabian, Bonvin, Alexandre, Kubitscheck, Ulrich, Breukink, Eefjan, Achorn, Catherine, Nitti, Anthony, Schwalen, Christopher J., Spoering, Amy L., Ling, Losee Lucy, Hughes, Dallas, Lelli, Moreno, Roos, Wouter H., Lewis, Kim, Schneider, Tanja, Weingarth, Markus
Publicado 2023

Teixobactin kills bacteria by a two-pronged attack on the cell envelope

por Shukla, Rhythm, Lavore, Francesca, Maity, Sourav, Derks, Maik G. N., Jones, Chelsea R., Vermeulen, Bram J. A., Melcrová, Adéla, Morris, Michael A., Becker, Lea Marie, Wang, Xiaoqi, Kumar, Raj, Medeiros-Silva, João, van Beekveld, Roy A. M., Bonvin, Alexandre M. J. J., Lorent, Joseph H., Lelli, Moreno, Nowick, James S., MacGillavry, Harold D., Peoples, Aaron J., Spoering, Amy L., Ling, Losee L., Hughes, Dallas E., Roos, Wouter H., Breukink, Eefjan, Lewis, Kim, Weingarth, Markus
Publicado 2022