Identification of Compounds That Promote Readthrough of Premature Termination Codons in the CFTR

por Smith, Emery, Dukovski, Danijela, Shumate, Justin, Scampavia, Louis, Miller, John P., Spicer, Timothy P.
Publicado 2020

Rescue of mutant gonadotropin-releasing hormone receptor function independent of cognate receptor activity

por Smith, Emery, Janovick, Jo Ann, Bannister, Thomas D., Shumate, Justin, Ganapathy, Vadivel, Scampavia, Louis, Spicer, Timothy P.
Publicado 2020

Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins

por Saha, Piyali, Shumate, Justin L, Caldwell, Jenna G, Elghobashi-Meinhardt, Nadia, Lu, Albert, Zhang, Lichao, Olsson, Niclas E, Elias, Joshua E, Pfeffer, Suzanne R
Publicado 2020

A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation

por Vides, Edmundo G, Adhikari, Ayan, Chiang, Claire Y, Lis, Pawel, Purlyte, Elena, Limouse, Charles, Shumate, Justin L, Spínola-Lasso, Elena, Dhekne, Herschel S, Alessi, Dario R, Pfeffer, Suzanne R
Publicado 2022