Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection

por Peritore-Galve, F. Christopher, Shupe, John A., Cave, Rory J., Childress, Kevin O., Washington, M. Kay, Kuehne, Sarah A., Lacy, D. Borden
Publicado 2022

Cecum axis (CecAx) preservation reveals physiological and pathological gradients in mouse gastrointestinal epithelium

por Lunnemann, Hannah M., Shealy, Nicolas G., Reyzer, Michelle L., Shupe, John A., Green, Emily H., Siddiqi, Uswah, Lacy, D. Borden, Byndloss, Mariana X., Markham, Nicholas O.
Publicado 2023

Mouse Spermatogenesis Requires Classical and Nonclassical Testosterone Signaling

por Toocheck, Corey, Clister, Terri, Shupe, John, Crum, Chelsea, Ravindranathan, Preethi, Lee, Tae-Kyung, Ahn, Jung-Mo, Raj, Ganesh V., Sukhwani, Meena, Orwig, Kyle E., Walker, William H.
Publicado 2015

Clostridioides difficile infection induces a rapid influx of bile acids into the gut during colonization of the host

por Wexler, Aaron G., Guiberson, Emma R., Beavers, William N., Shupe, John A., Washington, M. Kay, Lacy, D. Borden, Caprioli, Richard M., Spraggins, Jeffrey M., Skaar, Eric P.
Publicado 2021

Nanobodies against C. difficile TcdA and TcdB reveal unexpected neutralizing epitopes and provide a toolkit for toxin quantitation in vivo

por Kordus, Shannon L., Kroh, Heather K., Rodríguez, Rubén Cano, Shrem, Rebecca A., Peritore-Galve, F. Christopher, Shupe, John A., Wadzinski, Brian E., Lacy, D. Borden, Spiller, Benjamin W.
Publicado 2023

Increased intestinal permeability and downregulation of absorptive ion transporters Nhe3, Dra, and Sglt1 contribute to diarrhea during Clostridioides difficile infection

por Peritore-Galve, F. Christopher, Kaji, Izumi, Smith, Anna, Walker, Lauren M., Shupe, John A., Washington, M. Kay, Algood, Holly M. Scott, Dudeja, Pradeep K., Goldenring, James R., Lacy, D. Borden
Publicado 2023