Transcription factor UBF depletion in mouse cells results in downregulation of both downstream and upstream elements of the rRNA transcription network

por Theophanous, Andria, Christodoulou, Andri, Mattheou, Charalambia, Sibai, Dany S., Moss, Tom, Santama, Niovi
Publicado 2023

The chemotherapeutic agent CX-5461 irreversibly blocks RNA polymerase I initiation and promoter release to cause nucleolar disruption, DNA damage and cell inviability

por Mars, Jean-Clément, Tremblay, Michel G, Valere, Mélissa, Sibai, Dany S, Sabourin-Felix, Marianne, Lessard, Frédéric, Moss, Tom
Publicado 2020

Ribosomal DNA promoter recognition is determined in vivo by cooperation between UBTF1 and SL1 and is compromised in the UBTF-E210K neuroregression syndrome

por Tremblay, Michel G., Sibai, Dany S., Valère, Melissa, Mars, Jean-Clément, Lessard, Frédéric, Hori, Roderick T., Khan, Mohammad Moshahid, Stefanovsky, Victor Y., LeDoux, Mark S., Moss, Tom
Publicado 2022