The structural and functional workings of KEOPS

by Beenstock, Jonah, Sicheri, Frank
Published 2021

Putting the brakes on the unfolded protein response

by Sicheri, Frank, Silverman, Robert H.
Published 2011

Aurora A kinase activation: Different means to different ends

by Tavernier, Nicolas, Sicheri, Frank, Pintard, Lionel
Published 2021

Expression and purification of functional human glycogen synthase-1:glycogenin-1 complex in insect cells

by Hunter, Roger W., Zeqiraj, Elton, Morrice, Nicholas, Sicheri, Frank, Sakamoto, Kei
Published 2015

The ubiquitin interacting motifs of USP37 act on the proximal Ub of a di-Ub chain to enhance catalytic efficiency

by Manczyk, Noah, Veggiani, Gianluca, Teyra, Joan, Strilchuk, Amy W., Sidhu, Sachdev S., Sicheri, Frank
Published 2019

Structural and functional characterization of KEOPS dimerization by Pcc1 and its role in t(6)A biosynthesis

by Wan, Leo C.K., Pillon, Monica C., Thevakumaran, Neroshan, Sun, Yulong, Chakrabartty, Avi, Guarné, Alba, Kurinov, Igor, Durocher, Daniel, Sicheri, Frank
Published 2016

Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase

by Shehata, Saifeldin N., Hunter, Roger W., Ohta, Eriko, Peggie, Mark W., Lou, Hua Jane, Sicheri, Frank, Zeqiraj, Elton, Turk, Benjamin E., Sakamoto, Kei
Published 2012

Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay

by Koszela, Joanna, Pham, Nhan T., Evans, David, Mann, Stefan, Perez-Pi, Irene, Shave, Steven, Ceccarelli, Derek F. J., Sicheri, Frank, Tyers, Mike, Auer, Manfred
Published 2018

Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization

by Lavoie, Hugo, Thevakumaran, Neroshan, Gavory, Gwenaëlle, Li, John, Padeganeh, Abbas, Guiral, Sébastien, Duchaine, Jean, Mao, Daniel Y. L., Bouvier, Michel, Sicheri, Frank, Therrien, Marc
Published 2013

Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase

by Hunter, Roger W., Hughey, Curtis C., Lantier, Louise, Sundelin, Elias I., Peggie, Mark, Zeqiraj, Elton, Sicheri, Frank, Jessen, Niels, Wasserman, David H., Sakamoto, Kei
Published 2018

MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway

by Couzens, Amber L., Xiong, Shawn, Knight, James D. R., Mao, Daniel Y., Guettler, Sebastian, Picaud, Sarah, Kurinov, Igor, Filippakopoulos, Panagis, Sicheri, Frank, Gingras, Anne-Claude
Published 2017

A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay

by Alexander-Howden, Beatrice, Zhang, Li, van der Sloot, Almer M., Tollis, Sylvain, St-Cyr, Daniel J., Sicheri, Frank, Bird, Adrian P., Tyers, Mike, Lyst, Matthew J.
Published 2023

An allosteric conduit facilitates dynamic multisite substrate recognition by the SCF(Cdc4) ubiquitin ligase

by Csizmok, Veronika, Orlicky, Stephen, Cheng, Jing, Song, Jianhui, Bah, Alaji, Delgoshaie, Neda, Lin, Hong, Mittag, Tanja, Sicheri, Frank, Chan, Hue Sun, Tyers, Mike, Forman-Kay, Julie D.
Published 2017

Dissecting BAR Domain Function in the Yeast Amphiphysins Rvs161 and Rvs167 during Endocytosis

by Youn, Ji-Young, Friesen, Helena, Kishimoto, Takuma, Henne, William M., Kurat, Christoph F., Ye, Wei, Ceccarelli, Derek F., Sicheri, Frank, Kohlwein, Sepp D., McMahon, Harvey T., Andrews, Brenda J.
Published 2010

E2 enzyme inhibition by stabilization of a low affinity interface with ubiquitin

by Huang, Hao, Ceccarelli, Derek F, Orlicky, Stephen, St-Cyr, Daniel J., Ziemba, Amy, Garg, Pankaj, Plamondon, Serge, Auer, Manfred, Sidhu, Sachdev, Marinier, Anne, Kleiger, Gary, Tyers, Mike, Sicheri, Frank
Published 2013

Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment

by Xiong, Shawn, Lorenzen, Kristina, Couzens, Amber L., Templeton, Catherine M., Rajendran, Dushyandi, Mao, Daniel Y.L., Juang, Yu-Chi, Chiovitti, David, Kurinov, Igor, Guettler, Sebastian, Gingras, Anne-Claude, Sicheri, Frank
Published 2018

OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug

by Banerjee, Shuvojit, Gusho, Elona, Gaughan, Christina, Dong, Beihua, Gu, Xiaorong, Holvey-Bates, Elise, Talukdar, Manisha, Li, Yize, Weiss, Susan R., Sicheri, Frank, Saunthararajah, Yogen, Stark, George R., Silverman, Robert H.
Published 2019

53BP1 is a reader of the DNA damage-induced H2A Lys15 ubiquitin mark

by Fradet-Turcotte, Amélie, Canny, Marella D., Escribano-Díaz, Cristina, Orthwein, Alexandre, Leung, Charles C.Y., Huang, Hao, Landry, Marie-Claude, Kitevski-LeBlanc, Julianne, Noordermeer, Sylvie M., Sicheri, Frank, Durocher, Daniel
Published 2013

Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7

by Wan, Leo C.K., Maisonneuve, Pierre, Szilard, Rachel K., Lambert, Jean-Philippe, Ng, Timothy F., Manczyk, Noah, Huang, Hao, Laister, Rob, Caudy, Amy A., Gingras, Anne-Claude, Durocher, Daniel, Sicheri, Frank
Published 2017

Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system

by Wan, Leo C. K., Mao, Daniel Y. L., Neculai, Dante, Strecker, Jonathan, Chiovitti, David, Kurinov, Igor, Poda, Gennadiy, Thevakumaran, Neroshan, Yuan, Fang, Szilard, Rachel K., Lissina, Elena, Nislow, Corey, Caudy, Amy A., Durocher, Daniel, Sicheri, Frank
Published 2013