Hepatitis B Vaccines and HPV Vaccines Have Been Hailed as Major Public Health Achievements in Preventing Cancer—Could a Schistosomiasis Vaccine be the Third?

por Hsieh, Michael H., Brotherton, Julia M. L., Siddiqui, Afzal A.
Publicado 2015

Elucidation of Cellular Responses in Non-human Primates With Chronic Schistosomiasis Followed by Praziquantel Treatment

por Melkus, Michael W., Le, Loc, Siddiqui, Arif J., Molehin, Adebayo J., Zhang, Weidong, Lazarus, Samra, Siddiqui, Afzal A.
Publicado 2020

Immunological Considerations for Schistosoma Vaccine Development: Transitioning to Endemic Settings

por Driciru, Emmanuella, Koopman, Jan Pieter R., Cose, Stephen, Siddiqui, Afzal A., Yazdanbakhsh, Maria, Elliott, Alison M., Roestenberg, Meta
Publicado 2021

Schistosoma mansoni antigen Sm-p80: prophylactic efficacy using TLR4 agonist vaccine adjuvant glucopyranosyl lipid A-Alum in murine and non-human primate models

por Zhang, Weidong, Ahmad, Gul, Molehin, Adebayo J, Torben, Workineh, Le, Loc, Kim, Eunjee, Lazarus, Samra, Siddiqui, Arif J, Carter, Darrick, Siddiqui, Afzal A
Publicado 2018

Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons

por Rojo, Juan U., Melkus, Michael W., Kottapalli, Kameswara Rao, Okiya, Oscar E., Sudduth, Justin, Zhang, Weidong, Molehin, Adebayo J., Carter, Darrick, Siddiqui, Afzal A.
Publicado 2017

Process Development of Sj-p80: A Low-Cost Transmission-Blocking Veterinary Vaccine for Asiatic Schistosomiasis

por Molehin, Adebayo J., Gray, Sean A., Turner, Cheri, Davis, Jennifer, Zhang, Weidong, Khatoon, Sabiha, Rattan, Madison, Kernen, Rebecca, Peterson, Christopher, Sennoune, Souad R., Carter, Darrick, Siddiqui, Afzal A.
Publicado 2021

Chronic whipworm infection exacerbates Schistosoma mansoni egg-induced hepatopathology in non-human primates

por Le, Loc, Khatoon, Sabiha, Jiménez, Paola, Peterson, Christopher, Kernen, Rebecca, Zhang, Weidong, Molehin, Adebayo J., Lazarus, Samra, Sudduth, Justin, May, Jordan, Karmakar, Souvik, Rojo, Juan U., Ahmad, Gul, Torben, Workineh, Carey, David, Wolf, Roman F., Papin, James F., Siddiqui, Afzal A.
Publicado 2020

Fifteen Years of Sm-p80-Based Vaccine Trials in Nonhuman Primates: Antibodies From Vaccinated Baboons Confer Protection in vivo and in vitro From Schistosoma mansoni and Identifica...

por Zhang, Weidong, Le, Loc, Ahmad, Gul, Molehin, Adebayo J., Siddiqui, Arif J., Torben, Workineh, Karmakar, Souvik, Rojo, Juan U., Sennoune, Souad, Lazarus, Samara, Khatoon, Sabiha, Freeborn, Jasmin, Sudduth, Justin, Rezk, Ashraf F., Carey, David, Wolf, Roman F., Papin, James F., Damian, Ray, Gray, Sean A., Marks, Florian, Carter, Darrick, Siddiqui, Afzal A.
Publicado 2020

Establishing a single-sex controlled human Schistosoma mansoni infection model for Uganda: protocol for safety and dose-finding trial

por Abaasa, Andrew, Egesa, Moses, Driciru, Emmanuella, Koopman, Jan Pieter R, Kiyemba, Ronald, Sanya, Richard E, Nassuuna, Jacent, Ssali, Agnes, Kimbugwe, Geofrey, Wajja, Anne, van Dam, Govert J, Corstjens, Paul L A M, Cose, Stephen, Seeley, Janet, Kamuya, Dorcas, Webb, Emily L, Yazdanbakhsh, Maria, Kaleebu, Pontiano, Siddiqui, Afzal A, Kabatereine, Narcis, Tukahebwa, Edridah, Roestenberg, Meta, Elliott, Alison M
Publicado 2023