A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Pharmacodynamic Effects of VX-150, a Highly Selective Na(V)1.8 Inhibitor, in Healthy Male A...

por Hijma, Hemme J, Siebenga, Pieter S, de Kam, Marieke L, Groeneveld, Geert Jan
Publicado 2021

A phase I, randomized, double‐blind, placebo‐controlled, single‐ and multiple dose escalation study evaluating the safety, pharmacokinetics and pharmacodynamics of VX‐128, a highly...

por Hijma, Hemme J., van Brummelen, Emilie M. J., Siebenga, Pieter S., Groeneveld, Geert Jan
Publicado 2021

The ultraviolet B inflammation model: Postinflammatory hyperpigmentation and validation of a reduced UVB exposure paradigm for inducing hyperalgesia in healthy subjects

por Siebenga, Pieter S., van Amerongen, Guido, Klaassen, Erica S., de Kam, Marieke L., Rissmann, Robert, Groeneveld, Geert Jan
Publicado 2019

Lack of Detection of the Analgesic Properties of PF‐05089771, a Selective Na(v)1.7 Inhibitor, Using a Battery of Pain Models in Healthy Subjects

por Siebenga, Pieter, van Amerongen, Guido, Hay, Justin L., McDonnell, Aoibhinn, Gorman, Donal, Butt, Richard, Groeneveld, Geert Jan
Publicado 2019

Simultaneous tracking of psychophysical detection thresholds and evoked potentials to study nociceptive processing

por van den Berg, Boudewijn, Doll, Robert J., Mentink, Alexander L.H., Siebenga, Pieter S., Groeneveld, Geert J., Buitenweg, Jan R.
Publicado 2020

Reproducibility of a battery of human evoked pain models to detect pharmacological effects of analgesic drugs

por Siebenga, Pieter S., van Amerongen, Guido, Okkerse, Pieter, Denney, William S., Dua, Pinky, Butt, Richard P., Hay, Justin L., Groeneveld, Geert J.
Publicado 2019

Managing intravascular complications following treatment with calcium hydroxylapatite: An expert consensus

por van Loghem, Jani, Funt, David, Pavicic, Tatjana, Goldie, Kate, Yutskovskaya, Yana, Fabi, Sabrina, Siebenga, Pieter, Thuis, Job, Hkeik, Joseph, Kadouch, Jonathan, Prager, Welf, Azib, Nabila, Casabona, Gabriela, Dayan, Steve, Bay Aguilera, Shino, Snozzi, Philippe, Saeed, Peerooz
Publicado 2020

Pharmacological profile of ALKS 7119, an investigational compound evaluated for the treatment of neuropsychiatric disorders, in healthy volunteers

por Dijkstra, Francis M., Zuiker, Rob G. J. A., Siebenga, Pieter S., Leigh‐Pemberton, Richard A., Sun, Lei, Manthis, Joan D., de Kam, Marieke L., Lin, Richard, von Moltke, Lisa L., Rezendes, David, van Gerven, Joop M. A.
Publicado 2022