Synthesis of 1,2-Aminoalcohols through Enantioselective Aminoallylation of Ketones by Cu-Catalyzed Reductive Coupling

por Klake, Raphael K., Edwards, Mytia D., Sieber, Joshua D.
Publicado 2021

Rh-catalyzed reagent-free ring expansion of cyclobutenones and benzocyclobutenones

por Chen, Peng-hao, Sieber, Joshua, Senanayake, Chris H., Dong, Guangbin
Publicado 2015

Development of a Strategy for Linear-Selective Cu-Catalyzed Reductive Coupling of Ketones and Allenes for the Synthesis of Chiral γ-Hydroxyaldehyde Equivalents

por Klake, Raphael K., Gargaro, Samantha L., Gentry, Skyler L., Elele, Sharon O., Sieber, Joshua D.
Publicado 2019

Access to Chiral Diamine Derivatives through Stereoselective Cu-Catalyzed Reductive Coupling of Imines and Allenamides

por Agrawal, Toolika, Martin, Robert T., Collins, Stephen, Wilhelm, Zachary, Edwards, Mytia D., Gutierrez, Osvaldo, Sieber, Joshua D.
Publicado 2021

Access to a Catalytically Generated Umpolung Reagent through the Use of Cu-Catalyzed Reductive Coupling of Ketones and Allenes for the Synthesis of Chiral Vicinal Aminoalcohol Synt...

por Gargaro, Samantha L., Klake, Raphael K., Burns, Kevin L., Elele, Sharon O., Gentry, Skyler L., Sieber, Joshua D.
Publicado 2019

Expanding Access to Remdesivir via an Improved Pyrrolotriazine Synthesis: Supply Centered Synthesis

por Paymode, Dinesh J., Cardoso, Flavio S. P., Agrawal, Toolika, Tomlin, John W., Cook, Daniel W., Burns, Justina M., Stringham, Rodger W., Sieber, Joshua D., Gupton, B. Frank, Snead, David R.
Publicado 2020

Practical and Scalable Two-Step Process for 6-(2-Fluoro-4-nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane: A Key Intermediate of the Potent Antibiotic Drug Candidate TBI-223

por Cardoso, Flavio S.P., Kadam, Appasaheb L., Nelson, Ryan C., Tomlin, John W., Dahal, Dipendra, Kuehner, Christopher S., Gudvangen, Gard, Arduengo, Anthony J., Burns, Justina M., Aleshire, Sarah L., Snead, David R., Qu, Fengrui, Belmore, Ken, Ahmad, Saeed, Agrawal, Toolika, Sieber, Joshua D., Donsbach, Kai Oliver
Publicado 2023

Development of a Practical Synthesis of the 8-FDC Fragment of OPC-167832

por Gopalsamuthiram, Vijayagopal, Ho, Dang Binh, Peck, Cheryl L., Natarajan, Vasudevan, Agrawal, Toolika, Burns, Justina M., Bachert, John, Cook, Daniel W., Stringham, Rodger W., Nelson, Ryan, Ahmad, Saeed, Gupton, B. Frank, Snead, David R., McQuade, D. Tyler, Vaidyanathan, Rajappa, Donsbach, Kai, Sieber, Joshua D.
Publicado 2022

Copper-catalyzed asymmetric hydrogenation of 2-substituted ketones via dynamic kinetic resolution

por Zatolochnaya, Olga V., Rodríguez, Sonia, Zhang, Yongda, Lao, Kendricks S., Tcyrulnikov, Sergei, Li, Guisheng, Wang, Xiao-Jun, Qu, Bo, Biswas, Soumik, Mangunuru, Hari P. R., Rivalti, Daniel, Sieber, Joshua D., Desrosiers, Jean-Nicolas, Leung, Joyce C., Grinberg, Nelu, Lee, Heewon, Haddad, Nizar, Yee, Nathan K., Song, Jinhua J., Kozlowski, Marisa C., Senanayake, Chris H.
Publicado 2018