TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages

por Wajant, Harald, Siegmund, Daniela
Publicado 2019

Fn14 and TNFR2 as regulators of cytotoxic TNFR1 signaling

por Siegmund, Daniela, Zaitseva, Olena, Wajant, Harald
Publicado 2023

TNFR2 unlocks a RIPK1 kinase activity-dependent mode of proinflammatory TNFR1 signaling

por Siegmund, Daniela, Ehrenschwender, Martin, Wajant, Harald
Publicado 2018

TNF Receptor Associated Factor 2 (TRAF2) Signaling in Cancer

por Siegmund, Daniela, Wagner, Jennifer, Wajant, Harald
Publicado 2022

Activation of TNFR2 sensitizes macrophages for TNFR1-mediated necroptosis

por Siegmund, Daniela, Kums, Juliane, Ehrenschwender, Martin, Wajant, Harald
Publicado 2016

Redundant and receptor-specific activities of TRADD, RIPK1 and FADD in death receptor signaling

por Füllsack, Simone, Rosenthal, Alevtina, Wajant, Harald, Siegmund, Daniela
Publicado 2019

TRAF2 Controls Death Receptor-Induced Caspase-8 Processing and Facilitates Proinflammatory Signaling

por Kreckel, Jennifer, Anany, Mohammed A., Siegmund, Daniela, Wajant, Harald
Publicado 2019

Membrane lymphotoxin-α(2)β is a novel tumor necrosis factor (TNF) receptor 2 (TNFR2) agonist

por Kucka, Kirstin, Lang, Isabell, Zhang, Tengyu, Siegmund, Daniela, Medler, Juliane, Wajant, Harald
Publicado 2021

TNF Receptor-Associated Factor 1 is a Major Target of Soluble TWEAK

por Carmona Arana, José Antonio, Seher, Axel, Neumann, Manfred, Lang, Isabell, Siegmund, Daniela, Wajant, Harald
Publicado 2014

Soluble TNF-like weak inducer of apoptosis (TWEAK) enhances poly(I:C)-induced RIPK1-mediated necroptosis

por Anany, Mohamed A., Kreckel, Jennifer, Füllsack, Simone, Rosenthal, Alevtina, Otto, Christoph, Siegmund, Daniela, Wajant, Harald
Publicado 2018

The IKK Inhibitor Bay 11-7082 Induces Cell Death Independent from Inhibition of Activation of NFκB Transcription Factors

por Rauert-Wunderlich, Hilka, Siegmund, Daniela, Maier, Eduard, Giner, Tina, Bargou, Ralf C., Wajant, Harald, Stühmer, Thorsten
Publicado 2013

SMAC Mimetic BV6 Induces Cell Death in Monocytes and Maturation of Monocyte-Derived Dendritic Cells

por Müller-Sienerth, Nicole, Dietz, Lena, Holtz, Philipp, Kapp, Markus, Grigoleit, Götz Ulrich, Schmuck, Carsten, Wajant, Harald, Siegmund, Daniela
Publicado 2011

Assessment of TP53 lesions for p53 system functionality and drug resistance in multiple myeloma using an isogenic cell line model

por Munawar, Umair, Roth, Markus, Barrio, Santiago, Wajant, Harald, Siegmund, Daniela, Bargou, Ralf C., Kortüm, K. Martin, Stühmer, Thorsten
Publicado 2019

The NEDD8-activating enzyme inhibitor MLN4924 sensitizes a TNFR1(+) subgroup of multiple myeloma cells for TNF-induced cell death

por El-Mesery, Mohamed, Rosenthal, Tina, Rauert-Wunderlich, Hilka, Schreder, Martin, Stühmer, Thorsten, Leich, Ellen, Schlosser, Andreas, Ehrenschwender, Martin, Wajant, Harald, Siegmund, Daniela
Publicado 2019

NFκB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP

por Kreuz, Sebastian, Siegmund, Daniela, Rumpf, Jost-Julian, Samel, Dierk, Leverkus, Martin, Janssen, Ottmar, Häcker, Georg, Dittrich-Breiholz, Oliver, Kracht, Michael, Scheurich, Peter, Wajant, Harald
Publicado 2004

Hypertonicity-enforced BCL-2 addiction unleashes the cytotoxic potential of death receptors

por Sirtl, Simon, Knoll, Gertrud, Trinh, Dieu Thuy, Lang, Isabell, Siegmund, Daniela, Gross, Stefanie, Schuler-Thurner, Beatrice, Neubert, Patrick, Jantsch, Jonathan, Wajant, Harald, Ehrenschwender, Martin
Publicado 2018

Targeted delivery of CD40L promotes restricted activation of antigen-presenting cells and induction of cancer cell death

por Brunekreeft, Kim L, Strohm, Corinna, Gooden, Marloes J, Rybczynska, Anna A, Nijman, Hans W, Grigoleit, Götz U, Helfrich, Wijnand, Bremer, Edwin, Siegmund, Daniela, Wajant, Harald, de Bruyn, Marco
Publicado 2014