The synthesis of 2′-methylseleno adenosine and guanosine 5′-triphosphates

por Santner, Tobias, Siegmund, Vanessa, Marx, Andreas, Micura, Ronald
Publicado 2012

A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization

por Arras, Paul, Yoo, Han Byul, Pekar, Lukas, Schröter, Christian, Clarke, Thomas, Krah, Simon, Klewinghaus, Daniel, Siegmund, Vanessa, Evers, Andreas, Zielonka, Stefan
Publicado 2023

Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format

por Yanakieva, Desislava, Vollmer, Lena, Evers, Andreas, Siegmund, Vanessa, Arras, Paul, Pekar, Lukas, Doerner, Achim, Valldorf, Bernhard, Kolmar, Harald, Zielonka, Stefan, Krah, Simon
Publicado 2023

Spontaneous Isopeptide Bond Formation as a Powerful Tool for Engineering Site-Specific Antibody-Drug Conjugates

por Siegmund, Vanessa, Piater, Birgit, Zakeri, Bijan, Eichhorn, Thomas, Fischer, Frank, Deutsch, Carl, Becker, Stefan, Toleikis, Lars, Hock, Björn, Betz, Ulrich A. K., Kolmar, Harald
Publicado 2016

NKp46‐specific single domain antibodies enable facile engineering of various potent NK cell engager formats

por Lipinski, Britta, Arras, Paul, Pekar, Lukas, Klewinghaus, Daniel, Boje, Ammelie Svea, Krah, Simon, Zimmermann, Jasmin, Klausz, Katja, Peipp, Matthias, Siegmund, Vanessa, Evers, Andreas, Zielonka, Stefan
Publicado 2023

AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a pr...

por Arras, Paul, Yoo, Han Byul, Pekar, Lukas, Clarke, Thomas, Friedrich, Lukas, Schröter, Christian, Schanz, Jennifer, Tonillo, Jason, Siegmund, Vanessa, Doerner, Achim, Krah, Simon, Guarnera, Enrico, Zielonka, Stefan, Evers, Andreas
Publicado 2023

Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition

por Lipinski, Britta, Unmuth, Laura, Arras, Paul, Becker, Stefan, Bauer, Christina, Toleikis, Lars, Krah, Simon, Doerner, Achim, Yanakieva, Desislava, Boje, Ammelie Svea, Klausz, Katja, Peipp, Matthias, Siegmund, Vanessa, Evers, Andreas, Kolmar, Harald, Pekar, Lukas, Zielonka, Stefan
Publicado 2023