Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs

por Dilliard, Sean A., Siegwart, Daniel J.
Publicado 2023

Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing

por Wei, Tuo, Cheng, Qiang, Min, Yi-Li, Olson, Eric N., Siegwart, Daniel J.
Publicado 2020

Selective ORgan Targeting (SORT) nanoparticles for tissue specific mRNA delivery and CRISPR/Cas gene editing

por Cheng, Qiang, Wei, Tuo, Farbiak, Lukas, Johnson, Lindsay T., Dilliard, Sean A., Siegwart, Daniel J.
Publicado 2020

Membrane destabilizing ionizable phospholipids for organ selective mRNA delivery and CRISPR/Cas gene editing

por Liu, Shuai, Cheng, Qiang, Wei, Tuo, Yu, Xueliang, Johnson, Lindsay T., Farbiak, Lukas, Siegwart, Daniel J.
Publicado 2021

Enhancing CRISPR/Cas gene editing through modulating cellular mechanical properties for cancer therapy

por Zhang, Di, Wang, Guoxun, Yu, Xueliang, Wei, Tuo, Farbiak, Lukas, Johnson, Lindsay T., Taylor, Alan Mark, Xu, Jiazhu, Hong, Yi, Zhu, Hao, Siegwart, Daniel J.
Publicado 2022

Lung SORT LNPs enable precise homology-directed repair mediated CRISPR/Cas genome correction in cystic fibrosis models

por Wei, Tuo, Sun, Yehui, Cheng, Qiang, Chatterjee, Sumanta, Traylor, Zachary, Johnson, Lindsay T., Coquelin, Melissa L., Wang, Jialu, Torres, Michael J., Lian, Xizhen, Wang, Xu, Xiao, Yufen, Hodges, Craig A., Siegwart, Daniel J.
Publicado 2023

Precise let-7 expression levels balance organ regeneration against tumor suppression

por Wu, Linwei, Nguyen, Liem H, Zhou, Kejin, de Soysa, T Yvanka, Li, Lin, Miller, Jason B, Tian, Jianmin, Locker, Joseph, Zhang, Shuyuan, Shinoda, Gen, Seligson, Marc T, Zeitels, Lauren R, Acharya, Asha, Wang, Sam C, Mendell, Joshua T, He, Xiaoshun, Nishino, Jinsuke, Morrison, Sean J, Siegwart, Daniel J, Daley, George Q, Shyh-Chang, Ng, Zhu, Hao
Publicado 2015