Heterologous Expression of Ralp3 in Streptococcus pyogenes M2 and M6 Strains Affects the Virulence Characteristics

por Siemens, Nikolai, Kreikemeyer, Bernd
Publicado 2013

Streptococcus pyogenes (“Group A Streptococcus”), a Highly Adapted Human Pathogen—Potential Implications of Its Virulence Regulation for Epidemiology and Disease Management

por Siemens, Nikolai, Lütticken, Rudolf
Publicado 2021

Editorial: Streptococci in infectious diseases – pathogenic mechanisms and host immune responses

por Bergmann, Simone, Fulde, Marcus, Siemens, Nikolai
Publicado 2022

The Role of Streptococcal and Staphylococcal Exotoxins and Proteases in Human Necrotizing Soft Tissue Infections

por Shumba, Patience, Mairpady Shambat, Srikanth, Siemens, Nikolai
Publicado 2019

The Role of NLRP3 Inflammasome in Pneumococcal Infections

por Surabhi, Surabhi, Cuypers, Fabian, Hammerschmidt, Sven, Siemens, Nikolai
Publicado 2020

Port d’Entrée for Respiratory Infections – Does the Influenza A Virus Pave the Way for Bacteria?

por Siemens, Nikolai, Oehmcke-Hecht, Sonja, Mettenleiter, Thomas C., Kreikemeyer, Bernd, Valentin-Weigand, Peter, Hammerschmidt, Sven
Publicado 2017

Streptococcus pneumoniae Impairs Maturation of Human Dendritic Cells and Consequent Activation of CD4(+) T Cells via Pneumolysin

por Paulikat, Antje D., Tölken, Lea A., Jachmann, Lana H., Burchhardt, Gerhard, Hammerschmidt, Sven, Siemens, Nikolai
Publicado 2022

16HBE Cell Lipid Mediator Responses to Mono and Co-Infections with Respiratory Pathogens

por Schultz, Daniel, Surabhi, Surabhi, Stelling, Nicolas, Rothe, Michael, Methling, Karen, Hammerschmidt, Sven, Siemens, Nikolai, Lalk, Michael
Publicado 2020

Group B Streptococcal Hemolytic Pigment Impairs Platelet Function in a Two-Step Process

por Jahn, Kristin, Shumba, Patience, Quach, Phoenicia, Müsken, Mathias, Wesche, Jan, Greinacher, Andreas, Rajagopal, Lakshmi, Hammerschmidt, Sven, Siemens, Nikolai
Publicado 2022

Procoagulant Activity of Blood and Microvesicles Is Disturbed by Pneumococcal Pneumolysin, Which Interacts with Coagulation Factors

por Oehmcke-Hecht, Sonja, Maletzki, Claudia, Surabhi, Surabhi, Siemens, Nikolai, Khaimov, Valeria, John, Lisa Marie, Peter, Sina Mariella, Hammerschmidt, Sven, Kreikemeyer, Bernd
Publicado 2022

Increased cytotoxicity and streptolysin O activity in group G streptococcal strains causing invasive tissue infections

por Siemens, Nikolai, Kittang, Bård R., Chakrakodi, Bhavya, Oppegaard, Oddvar, Johansson, Linda, Bruun, Trond, Mylvaganam, Haima, Svensson, Mattias, Skrede, Steiner, Norrby-Teglund, Anna
Publicado 2015

Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse

por Chella Krishnan, Karthickeyan, Mukundan, Santhosh, Alagarsamy, Jeyashree, Hur, Junguk, Nookala, Suba, Siemens, Nikolai, Svensson, Mattias, Hyldegaard, Ole, Norrby-Teglund, Anna, Kotb, Malak
Publicado 2016

Differential neutrophil responses to bacterial stimuli: Streptococcal strains are potent inducers of heparin-binding protein and resistin-release

por Snäll, Johanna, Linnér, Anna, Uhlmann, Julia, Siemens, Nikolai, Ibold, Heike, Janos, Marton, Linder, Adam, Kreikemeyer, Bernd, Herwald, Heiko, Johansson, Linda, Norrby-Teglund, Anna
Publicado 2016

Impact of Pneumococcal and Viral Pneumonia on the Respiratory and Intestinal Tract Microbiomes of Mice

por Gierse, Laurin Christopher, Meene, Alexander, Skorka, Sebastian, Cuypers, Fabian, Surabhi, Surabhi, Ferrero-Bordera, Borja, Kreikemeyer, Bernd, Becher, Dörte, Hammerschmidt, Sven, Siemens, Nikolai, Urich, Tim, Riedel, Katharina
Publicado 2023

Bioactive lipid screening during respiratory tract infections with bacterial and viral pathogens in mice

por Schultz, Daniel, Cuypers, Fabian, Skorka, Sebastian B., Rockstroh, Jan, Gesell Salazar, Manuela, Krieger, Jakob, Albrecht, Dirk, Völker, Uwe, Hammerschmidt, Sven, Lalk, Michael, Siemens, Nikolai, Methling, Karen
Publicado 2022

Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology

por Mairpady Shambat, Srikanth, Chen, Puran, Nguyen Hoang, Anh Thu, Bergsten, Helena, Vandenesch, Francois, Siemens, Nikolai, Lina, Gerard, Monk, Ian R., Foster, Timothy J., Arakere, Gayathri, Svensson, Mattias, Norrby-Teglund, Anna
Publicado 2015

Innate immune responses at the asymptomatic stage of influenza A viral infections of Streptococcus pneumoniae colonized and non-colonized mice

por Cuypers, Fabian, Schäfer, Alexander, Skorka, Sebastian B., Surabhi, Surabhi, Tölken, Lea A., Paulikat, Antje D., Kohler, Thomas P., Otto, Saskia A., Mettenleiter, Thomas C., Hammerschmidt, Sven, Blohm, Ulrike, Siemens, Nikolai
Publicado 2021

Neutrophil-derived reactive agents induce a transient SpeB negative phenotype in Streptococcus pyogenes

por Shumba, Patience, Sura, Thomas, Moll, Kirsten, Chakrakodi, Bhavya, Tölken, Lea A., Hoßmann, Jörn, Hoff, Katharina J., Hyldegaard, Ole, Nekludov, Michael, Svensson, Mattias, Arnell, Per, Skrede, Steinar, Norrby-Teglund, Anna, Siemens, Nikolai
Publicado 2023

A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains

por Mairpady Shambat, Srikanth, Siemens, Nikolai, Monk, Ian R., Mohan, Disha B., Mukundan, Santhosh, Krishnan, Karthickeyan Chella, Prabhakara, Sushma, Snäll, Johanna, Kearns, Angela, Vandenesch, Francois, Svensson, Mattias, Kotb, Malak, Gopal, Balasubramanian, Arakere, Gayathri, Norrby-Teglund, Anna
Publicado 2016