Receptor Elimination by E3 Ubiquitin Ligase Recruitment (REULR): A Targeted Protein Degradation Toolbox

por Siepe, Dirk H., Picton, Lora K., Garcia, K. Christopher
Publicado 2023

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform

por Siepe, Dirk H, Henneberg, Lukas T, Wilson, Steven C, Hess, Gaelen T, Bassik, Michael C, Zinn, Kai, Garcia, K Christopher
Publicado 2022

A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability

por Vallon, Mario, Yuki, Kanako, Nguyen, Thi D., Chang, Junlei, Yuan, Jenny, Siepe, Dirk, Miao, Yi, Essler, Markus, Noda, Makoto, Garcia, K. Christopher, Kuo, Calvin J.
Publicado 2018

Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics

por Janetzko, John, Kise, Ryoji, Barsi-Rhyne, Benjamin, Siepe, Dirk H., Heydenreich, Franziska M., Kawakami, Kouki, Masureel, Matthieu, Maeda, Shoji, Garcia, K. Christopher, von Zastrow, Mark, Inoue, Asuka, Kobilka, Brian K.
Publicado 2022

Surrogate Wnt agonists that phenocopy canonical Wnt/β-catenin signaling

por Janda, Claudia Y., Dang, Luke T., You, Changjiang, Chang, Junlei, de Lau, Wim, Zhong, Zhendong A., Yan, Kelley S., Marecic, Owen, Siepe, Dirk, Li, Xingnan, Moody, James D., Williams, Bart O., Clevers, Hans, Piehler, Jacob, Baker, David, Kuo, Calvin J., Garcia, K. Christopher
Publicado 2017

A Human IgSF Cell-Surface Interactome Reveals a Complex Network of Protein-Protein Interactions

por Wojtowicz, Woj M., Vielmetter, Jost, Fernandes, Ricardo A., Siepe, Dirk H., Eastman, Catharine L., Chisholm, Gregory B., Cox, Sarah, Klock, Heath, Anderson, Paul W., Rue, Sarah M., Miller, Jessica J., Glaser, Scott M., Bragstad, Melisa L., Vance, Julie, Lam, Annie W., Lesley, Scott A., Zinn, Kai, Garcia, K. Christopher
Publicado 2020